Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Clinical Genomics Advanced Practice Provider
$110K - $130K *
Unlock potential by joining a dynamic Clinical Oncology Team, where you'll leverage your oncology and genomics expertise to enhance point-of-care products, drive clinical workflows, and support person...
1 week ago
Manager, Network Management (National Health Systems)
$54K - $159K *
Champion contract negotiations by driving initiatives, cultivating relationships, and ensuring compliance with performance goals. Leverage expertise to support cost-saving strategies and enhance cross...
Reposted 3 days ago
IT Operations and Asset Management Analyst
$80K - $95K *
Unlock potential by joining a dynamic team to enhance operational efficiency through budgeting, asset management, and data analysis, while supporting strategic initiatives and fostering relationships...
1 week ago
Nurse Practitioner - Harrisburg PA
$104K - $166K *
Lead the charge in delivering comprehensive field-based care, managing chronic diseases, and collaborating with an interdisciplinary team to enhance patient outcomes and prevent hospital visits for se...
3 days ago
$80K - $128K *
Analyze and monitor security alerts, investigate threats, and enhance SOC processes. Collaborate with teams to ensure cybersecurity measures are effective, while documenting incidents and providing te...
4 days ago
$80K - $128K *
Elevate cybersecurity operations by monitoring threats, analyzing network traffic, and coordinating incident responses. Collaborate with teams to enhance security measures and mentor junior analysts w...
6 days ago
Lead Data and AI Technical Program Manager
$120K - $145K *
Lead the charge in establishing data & AI governance standards, collaborating with technical teams to ensure high-quality, compliant data operations. Drive continuous improvement and compliance while...
1 week ago
$85K - $100K *
Innovate care for women and families across their lifespan by performing midwifery procedures, assessments, and treatments, ensuring comprehensive support and health management throughout various stag...
3 weeks ago
Associate Principal Scientist, Health Economic and Decision Sciences
$156K - $247K *
Champion innovative health economic modeling to enhance oncology product value. Collaborate with cross-functional teams and external partners to develop predictive models, ensuring impactful insights...
Reposted yesterday
Cyber Security Specialist Lead
$96K - $133K *
Support our cyber defense initiatives by leading incident response efforts, analyzing security events, and optimizing detection capabilities to enhance network security and protect sensitive data...
4 weeks ago
Experienced Clinical Research Associate | Regionally Aligned Across US
$80K - $95K *
Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...
1 week ago
$80K - $95K *
Elevate your career by driving growth and retention in hospital accounts. Leverage your sales expertise to identify opportunities, build relationships, and enhance service delivery in a dynamic field...
1 week ago
Certified Registered Nurse Anesthetist
$250K *
Champion a rewarding career as a Certified Registered Nurse Anesthetist, collaborating with a skilled team in a dynamic outpatient setting. Enjoy a balanced lifestyle with flexible shifts, diverse cas...
Reposted 2 weeks ago
$120K - $160K *
Transform data into actionable insights by owning the analytics pipeline from ingestion to visualization. Collaborate with cross-functional teams to create trusted models and metrics that empower deci...
1 week ago
$150K - $195K *
Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...
3 weeks ago
Client Manager, Healthcare Acquisition
$102K - $157K *
Unlock potential by driving new customer acquisition in healthcare. Engage C-suite leaders, champion innovative solutions, and lead complex sales cycles across AI and managed services to enhance patie...
3 weeks ago
Regional Vice President of Strategic Initiatives | PAM Health Corporate
$125K - $150K *
Grow your career with a leadership role directing referral development efforts, supervising a team of navigators, and implementing strategic initiatives to enhance organizational goals and patient adm...
1 week ago
$149K - $248K *
Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...
2 weeks ago
Senior Design Quality Engineer
$103K - $130K *
Unlock potential by ensuring top-tier quality and safety in product design. Collaborate with a dynamic team to oversee risk management and compliance, driving excellence in medical device engineering...
Reposted 3 weeks ago
Health Care Coordinator-Adult Community
$89K *
Join a dedicated team to oversee and coordinate comprehensive health care services, ensuring optimal medical support and wellness for individuals. Lead nursing staff and manage health care operations...
Yesterday
Director, Strategic Growth & Operations
$150K - $200K *
Empower strategic growth and operations by integrating cross-functional teams, aligning priorities, and driving initiatives to enhance study delivery and operational excellence in a dynamic environmen...
2 days ago
Physician, Advanced Endoscopist
$300K - $350K *
Develop your career with a leading healthcare provider, performing advanced endoscopic procedures while ensuring patient care excellence and collaborating with healthcare teams to manage gastrointesti...
Reposted yesterday
Director of Strategy and Integration | Pittsburgh LTACH
$110K - $130K *
Transform healthcare marketing by leading referral development and integration efforts. Oversee admissions processes, train staff, and implement strategic initiatives to enhance organizational goals a...
2 weeks ago
Lead, Conditions Management Marketing
$126K - $173K *
Transform member experiences by leading a dynamic marketing pod, driving execution and collaboration across teams to deliver personalized journeys efficiently and effectively, while maximizing platfor...
4 days ago
Senior Application Development Engineer
$87K - $161K *
Join a team that's dedicated to designing and implementing complex enterprise software solutions. Collaborate with diverse stakeholders to enhance data processes and support critical business function...
2 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.