Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
$46K - $122K *
Lead the charge in developing pricing strategies and financial models for PBM client contracts. Collaborate with sales and account teams to optimize revenue and profitability while presenting analyses...
3 days ago
Account Executive, Care Management
$80K - $95K *
Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...
Reposted 1 month ago
$79K - $127K *
Innovate with us to enhance data protection strategies, ensuring robust security and compliance across diverse platforms. Collaborate on complex projects, troubleshoot incidents, and drive improvement...
1 week ago
$88K - $105K *
Partner with us to enhance regulatory reporting processes through data analysis, compliance, and stakeholder collaboration. Shape strategic projects to optimize business processes, ensuring accuracy a...
Reposted 3 weeks ago
$88K - $140K *
Shape the future of public service by leading technology consulting projects that enhance operational efficiency and strategic goals for state and local agencies, ensuring compliance and delivering im...
2 weeks ago
Information Protection Advisor
$95K - $115K *
Shape the future of enterprise infrastructure by designing and supporting critical directory services like Active Directory and DNS, ensuring reliable access across a global landscape while leading pr...
Reposted today
$85K - $89K *
Drive educational excellence by planning and evaluating training programs for community staff, ensuring compliance with regulations while fostering a culture of continuous learning and improvement...
4 weeks ago
Physician Assistant or Nurse Practitioner- Hybrid - Surgical Oncology
$95K - $115K *
Join a team that's dedicated to delivering exceptional critical care services. This role involves managing acute and chronic health conditions, coordinating complex care, and ensuring effective commun...
Yesterday
Physician Assistant or Nurse Practitioner- Hybrid - Surgical Oncology
$95K - $115K *
Join a team that's dedicated to delivering exceptional specialty and critical care services. This role involves managing acute and chronic health conditions across diverse settings, ensuring high-qual...
2 days ago
Vice President, Business Development - Life Sciences
$175K - $210K *
Unlock potential by driving sales of real-world data solutions in life sciences. Collaborate with cross-functional teams to meet client needs and achieve growth targets while managing key relationship...
4 days ago
Vice President, Business Development - Life Sciences
$170K - $185K *
Transform the landscape of life sciences by driving sales of real-world data solutions. Collaborate with cross-functional teams to exceed sales goals and foster client relationships, contributing sign...
4 days ago
Director of Strategy and Integration | Heritage Valley LTACH
$100K - $120K *
Join a team that's dedicated to enhancing patient admissions through strategic marketing and relationship management. Lead and inspire staff while developing initiatives that align with organizational...
2 weeks ago
Nurse Practitioner or Physician Assistant - Outpatient Domain, Memory Center
$90K - $110K *
Transform healthcare delivery by providing critical care services in diverse settings, focusing on chronic conditions. Collaborate with physicians, educate patients, and ensure compliance with standar...
1 week ago
Senior Manager Medical Economics
$82K - $182K *
Analyze healthcare costs and quality outcomes to drive value-based care strategies, collaborating with clinical and financial teams. Lead data-driven insights and financial modeling to enhance operati...
Reposted 4 days ago
$80K - $105K *
Serve as a key support for investment consulting relationships, ensuring timely, accurate reporting and client communication. Collaborate with consultants and teams to enhance client service and contr...
3 weeks ago
$198K - $297K *
Engage in a dynamic role that empowers team collaboration and drives results in a leading organization recognized for innovation and excellence in performance, fostering an environment of growth and p...
Reposted 2 weeks ago
$64K - $107K *
Champion the execution of cross-functional initiatives, managing systems and technical projects to enhance operational efficiency. Collaborate with stakeholders to document requirements, conduct testi...
2 days ago
Director, Applications, Lab Systems
$181K - $291K *
Lead the charge in managing the full systems development lifecycle for enterprise applications, ensuring data quality and integrity while evolving best practices across healthcare operations and suppo...
4 days ago
Supervisor, Healthcare Revenue Cycle Consulting
$95K - $192K *
Elevate your career by leading a dynamic consulting team focused on optimizing revenue cycle operations in healthcare. Drive impactful projects, enhance client service, and mentor junior professionals...
1 week ago
Senior Research Biostatistician
$95K - $115K *
Elevate your career by providing biostatistical expertise to support cancer research. Collaborate with investigators, analyze data, and contribute to impactful publications while ensuring the integrit...
3 days ago
$140K - $270K *
Unlock potential by designing and deploying scalable AI systems that transform healthcare workflows. Collaborate with cross-functional teams to solve complex business challenges and drive measurable o...
3 weeks ago
AfroTech 2026 Business Analyst
$80K - $95K *
Unlock potential by collaborating with public safety agencies to design and implement solutions that enhance operational efficiency. Join a dynamic team focused on delivering impactful software config...
5 days ago
Product Manager, National Center for Clinical Trials (NCCT)
$122K - $183K *
Transform how we operate by leading technology-driven initiatives that enhance business capabilities. Collaborate with cross-functional teams to define product strategies and drive measurable outcomes...
Yesterday
Senior Analyst, Decision Science (Market Analyst)
$105K - $129K *
Drive impactful market analysis and reporting as a Senior Analyst, leveraging data to guide strategic investments and growth opportunities. Collaborate with teams to enhance decision-making and optimi...
1 week ago
Senior Analyst, HR Services/Analyst, HR Services
$88K - $98K *
Elevate HR operations by providing expert transactional support and coaching. Drive efficiency and service excellence through innovative solutions and data audits, while managing complex escalations a...
Reposted 3 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.