Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Hospice Director of Nursing RN
$80K - $95K *
Champion exceptional hospice care by leading a dedicated team, ensuring compliance, and enhancing patient experiences. Drive quality initiatives and community outreach while fostering a supportive env...
1 week ago
Hospice Director of Nursing RN
$80K - $95K *
Elevate patient care by leading hospice services, coordinating teams, and ensuring compliance. Drive quality improvement initiatives while serving as a community liaison to enhance hospice education a...
2 weeks ago
$90K - $110K *
Lead the charge in optimizing business processes and technology solutions, serving as the primary liaison between stakeholders and technical teams to enhance operational efficiency and customer experi...
1 week ago
$114K - $218K *
Partner with us to drive insights and optimization strategies that enhance marketing effectiveness across diverse channels. You'll leverage data analytics, visualization, and collaboration to propel b...
Reposted 4 weeks ago
Project Manager II/Senior, Real World Evidence/ Late Phase Research
$95K - $115K *
Lead the charge in overseeing RWE clinical studies, ensuring quality and client satisfaction from planning to completion. Manage multi-functional teams and coordinate project timelines, budgets, and d...
5 days ago
$121K - $240K *
Architect and evolve enterprise Salesforce architecture, driving scalable solutions aligned with commercial strategy, managing integration with Certinia, and leading AI inclusion for Sales, Marketing...
Reposted 4 days ago
$80K - $95K *
Drive strategic management of service line integration, ensuring high-quality clinical documentation integrity. Collaborate with teams to enhance compliance and optimize outcomes while performing inde...
1 week ago
$186K - $250K *
Unlock potential by leading a high-performing HEOR team to drive payer engagement and market access strategies, translating complex data into actionable insights that enhance patient access to innovat...
2 weeks ago
$120K - $132K *
Join a team that's dedicated to enhancing cybersecurity measures across cloud environments. Lead initiatives in data protection, compliance, and security awareness while mentoring peers and implementi...
1 week ago
Medical Director, Post Acute Care
$207K - $346K *
Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...
Reposted today
Executive Director, IT Quality & Compliance
$150K - $180K *
Champion IT quality and compliance initiatives, leading a global team in developing validation strategies, ensuring regulatory adherence, and driving risk assessments across diverse technologies and o...
Reposted 3 weeks ago
Senior Technical Consultant - Data & Analytics
$160K - $200K *
Lead the charge in designing and implementing scalable data solutions, orchestrating pipelines, and supporting advanced analytics in cloud environments. Collaborate with teams to deliver robust data a...
2 weeks ago
Regional Health Physicist - South Central US
$110K - $151K *
Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...
6 days ago
In-Home Traveler Physician Full Time - DC
$174K - $374K *
Engage with patients in their homes to conduct health evaluations, build relationships, and bridge care gaps. This role demands extensive travel and flexibility to provide personalized care and diagno...
3 weeks ago
Registered Nurse (RN) - Vascular Lab
$79K - $118K *
Champion advanced cardiovascular care by supporting vascular and interventional procedures in a dynamic, high-acuity environment. Collaborate with a specialized team to enhance patient outcomes while...
1 week ago
Registered Nurse II Women's Care Sexual Health
$73K - $110K *
Deliver compassionate care as a Registered Nurse, supporting women's sexual health services through patient education, medication management, and procedural assistance in a collaborative clinic enviro...
1 week ago
Senior Technical Product Manager - Insurance Products & Benefits
$104K - $143K *
Lead the charge in developing and delivering innovative technology solutions for managing Medicare/Medicaid plans. Collaborate with cross-functional teams to drive product vision, strategy, and execut...
Reposted today
$115K - $158K *
Shape the future of behavioral health care by leading program operations, analytics, and performance management. Collaborate with clinical teams to enhance patient care through data-driven insights an...
1 week ago
$115K - $158K *
Transform healthcare delivery by leading analytics and operations for a behavioral health program. Collaborate with clinical teams to enhance performance, drive strategic initiatives, and ensure effec...
1 week ago
$115K - $158K *
Manage and enhance program operations for a behavioral health initiative, driving performance analytics and strategic improvements while collaborating with clinical and operational teams to optimize c...
1 week ago
$115K - $158K *
Accelerate progress at our behavioral health program by leading operations, analytics, and performance management. Collaborate with clinical teams to enhance care delivery and drive strategic initiati...
1 week ago
$115K - $158K *
Lead the charge in enhancing behavioral health program operations, driving analytics, and fostering collaboration across clinical teams to optimize patient care delivery and performance management in...
1 week ago
$95K - $115K *
Drive high-quality clinical data outputs by performing statistical programming and ensuring compliance with protocols and regulations. Collaborate with cross-functional teams to maintain data integrit...
Yesterday
$95K - $206K *
Join a dynamic team as a Clinician Player Coach, mentoring peers while delivering high-quality in-home evaluations. Balance clinical duties with mentorship, ensuring exceptional care and support for n...
3 weeks ago
$91K - $136K *
Help us enhance patient well-being by evaluating needs and implementing tailored treatment plans. Collaborate with healthcare teams to deliver effective physical therapy in home settings, ensuring opt...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.