Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Nurse Practitioner/Physician Assistant - Director of Advanced Practice for Behavioral Health
$110K - $130K *
Discover the opportunity to lead and optimize Advanced Practice Providers in a dynamic behavioral health setting. Collaborate across interprofessional teams to improve service delivery, enhance access...
Reposted 5 days ago
Technical SME - Data Architecture / Data Ware
$110K - $130K *
Empower your career with senior-level expertise in data architecture and warehousing. Drive data integration and management, ensuring effective solutions for Occupational Environmental Health practice...
3 weeks ago
Area Vice President, Anesthesia
$78K - $125K *
Transform healthcare delivery by leading operations across various service lines, ensuring clinical quality, patient safety, and efficiency. Collaborate with leadership to drive strategic initiatives...
Reposted 3 weeks ago
Director, HCS Client Strategy & Product
$140K - $180K *
Unlock potential by leading client strategy and product initiatives, driving growth through market insights and cross-functional collaboration. Shape solutions that enhance client value and optimize H...
2 weeks ago
APP (NP/PA) Primary Care Inbox Management (remote)
$119K - $134K *
Partner with us to enhance patient care by supporting primary care teams remotely. Collaborate with on-site providers to manage patient needs effectively, ensuring seamless communication and coordinat...
1 week ago
Resource Registered Nurse - ICU Float Pool
$79K - $118K *
Deliver exceptional nursing care by assessing, planning, and implementing patient-centered strategies across multiple facilities. Collaborate with teams to enhance outcomes while promoting safety and...
3 days ago
$90K - $115K *
Drive the administration of OneStream, supporting FP&A and Accounts Payable teams. Enhance reporting, manage data integrations, and collaborate with Finance and IT to optimize processes and improve ef...
1 week ago
$110K - $130K *
Elevate client relationships by leading Client Success teams to ensure operational excellence, proactive issue resolution, and strategic growth, while fostering collaboration across departments to enh...
1 week ago
Product Manager - Clinical Member Data
$86K - $138K *
Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...
1 week ago
Lead Director, Commercial Product Execution National Accounts
$100K - $231K *
Lead the charge in product execution, driving growth and market penetration by collaborating with sales teams to develop strategies and equip them with tools for success. Enhance customer value throug...
Reposted 3 weeks ago
$76K - $120K *
Take ownership of critical operational pipelines as a Research Statistician, executing analyses and improving processes to ensure the SAT Suite runs smoothly. Collaborate with cross-functional teams t...
1 week ago
Manager Clinical Registry Operations - Trauma / Orthopedic
$99K - $148K *
Transform your career with a leadership role overseeing clinical data management, ensuring compliance, and driving quality improvement initiatives across the enterprise. Collaborate with diverse teams...
5 days ago
$113K - $188K *
Transform data into insights by developing cutting-edge machine learning models. Collaborate with multidisciplinary teams to address complex business needs using advanced analytics, ensuring data-driv...
Reposted 1 week ago
Data Analytics Program Manager
$120K - $130K *
Unlock potential by managing complex datasets to drive decisions across a fast-scaling energy planning function. Collaborate with cross-functional teams to ensure data integrity and operational effici...
1 week ago
Director, Optimization Analyst
$88K - $140K *
Drive the development of predictive analytics models to enhance digital assessment operations, collaborating across teams to optimize decision-making and reduce costs while supporting strategic goals...
3 weeks ago
Solution Management Assoc Director (GMI)
$99K - $275K *
Join a dynamic team to drive technology strategy into actionable product roadmaps, enhancing operational efficiency and customer value. Collaborate across functions to shape innovative solutions that...
1 week ago
$64K - $108K *
Deliver strategic financial insights and support decision-making through advanced analysis, forecasting, and budgeting. Collaborate with finance and business leaders to improve performance visibility...
Reposted 1 week ago
Program Evaluator - State & Local Outcomes (Human Services / BH / Justice)
$80K - $95K *
Analyze and lead evaluations for human-services and public programs, creating frameworks and performance measures. Collaborate with stakeholders to translate findings into actionable insights, ensurin...
2 weeks ago
Vice President, Medicaid Partnerships
$150K *
Elevate Medicaid partnerships by driving strategic sales initiatives, securing contracts, and fostering client relationships. Lead a team to achieve growth targets while navigating market dynamics and...
2 weeks ago
$71K - $107K *
Join a team that's dedicated to providing high-quality nursing care in patients' homes. Collaborate with healthcare professionals to develop and implement care plans, ensuring continuity and excellenc...
3 weeks ago
Academic Chair of Internal Medicine - Greenville, North Carolina
$210K - $250K *
Lead the Department of Internal Medicine, overseeing clinical, academic, and operational programs while driving strategic initiatives and faculty development in a dynamic academic medical environment...
3 days ago
Nurse Manager Cardiac Progressive Care
$88K - $105K *
Empower exceptional nursing leadership and optimize clinical operations in a dynamic, patient-focused environment, ensuring quality care and compliance while fostering staff development and collaborat...
Reposted 3 days ago
Clinical Pharmacist, Acute Care Pharmacy, Hybrid, Hospital at Home and Internal Medicine
$114K - $171K *
Join a collaborative team to deliver patient-centered pharmaceutical care in acute internal medicine, enhance therapeutic outcomes, and educate healthcare professionals, all while contributing to inno...
Reposted 2 weeks ago
Primary Care Nurse Practitioner/Physician Assistant
$90K - $110K *
Join us to provide comprehensive primary care in skilled nursing and senior living communities, focusing on chronic disease management and interdisciplinary collaboration to enhance patient outcomes a...
6 days ago
$85K - $110K *
Advance operational excellence by leading investigations into quality and safety events. Collaborate with cross-functional teams to identify root causes and implement corrective actions, enhancing rel...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.