Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior Statistical Programmer/Analyst Consultant (Need solid oncology background) Remote in US
$110K - $130K *
Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...
1 week ago
Information Security Analyst TIAA
$93K - $129K *
Lead the charge in enhancing cybersecurity awareness through engaging events and communications. Collaborate with internal teams and external partners to drive impactful initiatives that educate and e...
1 week ago
Technology/Healthcare Delivery Lead Associate Manager - Payer
$70K - $196K *
Partner with us to drive successful technology programs in healthcare. Leverage your analytical and communication skills to support cross-functional teams, ensuring high-quality deliverables and effec...
3 days ago
Technology/Healthcare Delivery Lead Associate Manager - Payer
$70K - $196K *
Lead the charge in delivering complex technology programs for healthcare clients. Collaborate with cross-functional teams to create high-quality deliverables, analyze challenges, and ensure successful...
3 days ago
Associate Director - Technology, AI, & Digital Solutions - Healthcare
$150K - $250K *
Transform healthcare technology engagements by leading multidisciplinary teams, developing actionable strategies, and implementing AI and automation solutions to enhance operational efficiency and cli...
3 days ago
Healthcare Tech Manager - Epic Patient Access
$130K - $150K *
Drive impactful solutions as a Healthcare Technology Manager, optimizing Epic Patient Access systems. Collaborate with clients and teams to enhance workflows and deliver sustainable results in a suppo...
1 week ago
$75K - $158K *
Empower cross-functional teams as a Business Analyst, driving Agile practices, refining backlogs, and aligning business objectives with technical execution to enhance project outcomes and stakeholder...
Reposted 1 week ago
Senior Software Business Analyst
$107K - $147K *
Champion the integration of business needs and technical solutions, driving product delivery through collaboration with stakeholders. Leverage your expertise to translate requirements into actionable...
3 days ago
Senior Application System Analyst
$98K - $156K *
Lead the charge in transforming complex business needs into precise system solutions. Collaborate with cross-functional teams to develop functional designs that drive successful IT implementations and...
Yesterday
Senior Life Sciences Analyst, AI Model Training
$110K - $130K *
Empower life sciences innovation by evaluating AI model outputs, ensuring quality and accuracy. Collaborate with cross-functional teams to enhance predictive analytics and insights, bridging clinical...
1 week ago
Systems Administrator IV, Health Systems
$103K - $134K *
Join us in optimizing healthcare technology by leading the analysis, design, and support of Epic applications. Collaborate with clinical and IT teams to enhance system functionality and improve patien...
Reposted 5 days ago
Senior Analyst, Client Financial Operations
$76K - $96K *
Unlock the potential of financial operations by overseeing invoicing processes for non-core programs. Drive improvements, analyze data, and collaborate with teams to enhance accuracy and efficiency in...
1 week ago
Solution Consultant, Senior (Healthcare)
$110K - $130K *
Drive your career with a senior role that leverages healthcare expertise to support sales processes, lead solution demonstrations, and collaborate with teams to enhance customer success and revenue gr...
2 weeks ago
Systems Administrator IV, Health Systems
$103K - $134K *
Elevate the quality of patient care by leading the analysis, design, and support of Epic applications. Collaborate with clinical and IT teams to optimize system functionality and enhance user experien...
Reposted 5 days ago
Systems Analyst (Insurance) - 177050
$115K - $130K *
Join a team that's dedicated to optimizing insurance systems through SQL-driven solutions. Collaborate with stakeholders to enhance policy administration platforms and drive system improvements in a h...
3 days ago
Lead RN, Utilization Management
$100K - $130K *
Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...
5 days ago
Manager, Clinical Data Acquisition
$73K - $130K *
Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...
3 weeks ago
Client Success Manager, Payer Retrieval
$108K - $130K *
Unlock your potential by leading customer projects, ensuring seamless communication, and driving success in healthcare solutions. Collaborate with diverse teams to enhance client satisfaction and oper...
1 week ago
$173K - $245K *
Unlock insights through data analytics and experimentation to enhance credit risk management. Collaborate with cross-functional teams to optimize policies, monitor performance, and drive strategic gro...
2 weeks ago
Senior Director, Strategic Growth Analytics
$170K - $200K *
Champion strategic growth initiatives by leading analytics to drive measurable business performance and enhance decision-making across a global organization through advanced insights and AI capabiliti...
Reposted 3 weeks ago
$95K - $115K *
Champion healthcare solutions by managing integrations and providing expert support. Drive projects and improve processes as a Senior Interface Analyst in a dynamic and innovative environment, ensurin...
Reposted yesterday
$115K - $130K *
Join a dynamic team as you provide essential IT support to a distributed workforce. Leverage your troubleshooting skills to resolve technical issues, enhance user experience, and contribute to a colla...
Reposted today
$95K - $115K *
Empower our mission by leading IT audits that assess risk and enhance controls. Collaborate across teams to ensure compliance and operational effectiveness while mentoring fellow auditors and deliveri...
1 month ago
Senior Machine Learning Engineer
$130K - $155K *
Shape the future of AI by designing and implementing advanced machine learning solutions. Collaborate with teams to deliver innovative systems, leveraging your expertise in software engineering and ba...
1 week ago
$110K - $130K *
Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.