Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$100K - $120K *

Drive comprehensive health assessments by traveling to patients' homes, ensuring accurate documentation and patient education. Collaborate with healthcare teams to enhance care continuity while managi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $175K *

Transform revenue operations by leading systems, data, and processes that unify Sales, Marketing, and Customer Success into a streamlined revenue engine, driving growth and efficiency across the organ...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $215K *

Empower strategic growth by managing health plan partnerships, driving revenue, and enhancing client relationships. Utilize your expertise in managed care to deliver impactful solutions and ensure cli...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $254K *

Oversee and manage large-scale, multi-national projects, ensuring successful delivery through direct team leadership and cross-functional collaboration, while maintaining high quality and financial pe...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $100K *

Optimize clinical trial execution by managing site relationships, ensuring compliance, and safeguarding patient safety. Play a key role in monitoring, training, and resolving issues to enhance study q...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$101K - $152K *

Join a team that's driving organizational change and fostering continuous improvement. As a key player, you'll enhance operational efficiency and implement strategic initiatives across departments, en...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$90K - $120K *

Advance strategic initiatives by collaborating across teams to launch innovative data tools and insurance programs. Drive project management efforts and contribute to executive presentations that shap...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Optimize predictive modeling initiatives by designing and implementing advanced actuarial pricing models. Collaborate with cross-functional teams to ensure compliance and drive strategic pricing solut...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock the potential of data by designing integrations and analytics solutions that empower businesses to make informed decisions. Collaborate with clients and leverage modern technologies to transfor...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $205K *

Champion client success by managing strategic accounts, driving growth, and enhancing relationships with health plans. Collaborate cross-functionally to deliver tailored solutions and ensure seamless...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $150K *

Elevate procurement operations by managing vendor coordination, documentation, and process consistency. This role focuses on execution and queue management, ensuring timely and organized procurement s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$250K - $275K *

Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Drive risk assessments and vulnerability testing to enhance application security. Collaborate with IT teams to implement security solutions, prepare reports, and ensure compliance with regulations whi...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$87K - $108K *

Elevate your career with a rewarding role in speech therapy, providing patient-centered care in a supportive environment. Join a dedicated team focused on making a meaningful impact in skilled nursing...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$179K - $190K *

Shape the future of payroll and HR services by leading strategic initiatives, optimizing operations, and ensuring compliance across the employee lifecycle. Drive excellence in service delivery while f...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$95K - $115K *

Drive impactful pricing strategies by developing predictive models that enhance segmentation and lifetime value. Collaborate with cross-functional teams to ensure compliance and deliver high-quality a...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Unlock your potential as a Data Engineer, driving innovative data solutions and optimizing data pipelines. Collaborate with cross-functional teams to enhance data quality and support analytics initiat...

Today

  •   5 - 7 years exp.  •   Information Technology

$67K - $182K *

Unlock your potential as you lead proposal development and client audit responses, ensuring clarity and compliance in complex healthcare contracts. Drive project management for implementations while c...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$147K - $220K *

Champion transformative health solutions by managing key client relationships, driving sales, and collaborating across teams to enhance Verily's impact in Life Sciences. Leverage expertise to unlock n...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$112K - $126K *

Join a team that's driving impactful healthcare solutions by managing complex projects from initiation to stabilization. Collaborate with cross-functional teams to ensure timely delivery and high-qual...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$100K - $118K *

Optimize information systems integrity and compliance through comprehensive audits. Collaborate with stakeholders to ensure timely responses and effective documentation, while enhancing IT controls an...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$223K - $313K *

Join a distinguished team of physicians to enhance inpatient care quality through expert clinical reviews and utilization management, impacting patient outcomes while enjoying a structured, collaborat...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$128K - $252K *

Drive the evolution of people analytics by building data pipelines, dashboards, and insights that empower leaders with decision-ready information. Collaborate across teams to enhance data usability an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$123K - $142K *

Lead the execution of Enterprise Risk Management programs, collaborating across teams to enhance risk governance and training initiatives. Drive project management efforts, ensuring timely delivery an...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.