Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$75K - $105K *

Empower healthcare delivery by ensuring coding accuracy as you analyze medical records, identify improvement opportunities, and enhance AI diagnostic models to uphold high-quality standards in inpatie...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$76K - $105K *

Support day-to-day operations for investment teams, collaborating across functions to enhance processes, manage budgets, and drive special projects from planning to implementation, ensuring alignment...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Transform payment strategies by analyzing interchange and routing data to optimize costs and enhance performance. Leverage advanced analytics and automation to deliver actionable insights for stakehol...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$108K - $130K *

Join a team that's dedicated to enhancing cybersecurity by assessing vulnerabilities across enterprise systems and guiding remediation efforts. This senior role offers mentorship opportunities while d...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $98K *

Join a dynamic team to evaluate and enhance the financial health of affordable housing organizations nationwide. Utilize advanced analytics and strategic insights to support sustainable growth and ris...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$162K - $224K *

Elevate healthcare solutions by driving business development in neurodegenerative disease pathways. Collaborate with health systems and stakeholders to identify needs, develop strategies, and create i...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $158K *

Innovate defensive cybersecurity strategies by analyzing data trends, developing countermeasures, and collaborating with teams to prevent compromises and enhance enterprise security. Drive proactive m...

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$102K - $170K *

Lead the design and implementation of AI solutions for public health data exchange. Guide teams in creating scalable, secure systems that meet governance and interoperability standards while enhancing...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Business Services

$175K - $334K *

Lead the charge in shaping technology product strategies to enhance patient care pathways, optimize medical costs, and partner with clinical leaders, driving outcomes through innovative tech solutions...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $96K *

Empower your career by joining our dynamic team to drive client engagement, identify opportunities, and develop innovative sales strategies. Collaborate with stakeholders and enhance your skills in a...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$111K - $139K *

Elevate your career by driving innovation in IT service management. Leverage AI solutions to enhance processes, improve customer experiences, and lead cross-functional initiatives that shape the futur...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$74K - $92K *

Empower our channel partner division by managing operational activities, coordinating RFPs, and driving cross-functional collaboration to enhance sales and partner engagement. Your insights will shape...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$215K - $408K *

Drive medical management and quality improvement initiatives, ensuring effective utilization and cost containment while collaborating with clinical teams to enhance patient care and outcomes across mu...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Grow your career with a dynamic role in behavioral health, leading medical management and quality improvement initiatives. Collaborate across diverse markets to enhance care delivery and support conti...

Missouri, USRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Drive medical leadership in quality improvement and utilization management, ensuring effective care delivery and cost containment. Collaborate with clinical teams to enhance patient outcomes and suppo...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $90K *

Unlock potential by providing expert lifecycle acquisition support for NGA programs, developing key documentation, and ensuring timely procurement actions through collaboration with technical and fina...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$76K - $88K *

Join us to enhance patient care through compliance, clinical judgment, and teamwork. Collaborate with interdisciplinary teams to ensure safety and quality standards while advocating for patients and f...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $146K *

Partner with us to provide clinical support for contrast media, delivering education and product expertise to healthcare professionals while collaborating with internal teams to enhance patient care a...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Unlock potential by leading the design and optimization of enterprise workflows. Collaborate with cross-functional teams to enhance operational efficiency and drive data-driven decisions within a dyna...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $300K *

Transform patient care by joining a dynamic team of Radiologists, leveraging cutting-edge imaging technology and collaborating on complex cases to enhance diagnostic accuracy and efficiency in a fast...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $159K *

Drive privacy excellence by executing assessments and managing risks across products. Collaborate with Legal, Product, and Engineering to embed privacy by design and enhance frameworks that protect cu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Shape global sourcing strategies and enhance procurement processes through data analytics, supplier performance management, and strategic initiatives. Collaborate across teams to drive savings and ens...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$102K - $170K *

Elevate your career by driving operational improvements in healthcare. Collaborate with clients to enhance performance through data analysis and strategic workflow redesign, ensuring impactful outcome...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Optimize contact center strategies by leveraging virtual agent and IVR technologies. Collaborate with stakeholders to enhance operational workflows and drive performance through data analysis and inno...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.