Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Analyst: Security Compliance & Assurance
$95K - $115K *
Join a team that drives security compliance and audit initiatives, ensuring adherence to industry standards. Provide oversight, validate controls, and empower stakeholders through transparency and eff...
Reposted yesterday
Channel Development, Lead Retention
$115K - $158K *
Drive strategies to enhance customer engagement and retention for pharmacy services. Collaborate with cross-functional teams to optimize member experiences, increase auto-refill adoption, and boost pr...
Reposted 1 week ago
Remote Clinical Recruiter, Registered Dietitians
$85K - $95K *
Join a team that's redefining clinical recruitment by leading full-cycle hiring for Registered Dietitians. Drive innovative sourcing strategies and ensure a seamless candidate experience in a fast-pac...
4 days ago
Director, Operations Analytics & Workforce Strategy
$125K - $150K *
Join a dynamic team to drive operational excellence through data-driven strategies. Lead workforce planning, enhance performance metrics, and collaborate across functions to optimize patient services...
1 week ago
$120K - $145K *
Champion innovative solutions by collaborating with clients to align IT capabilities with business goals. Leverage your expertise in enterprise architecture to drive strategic initiatives and optimize...
3 weeks ago
Clinical System Programmer Developer (Allscripts/MLM)
$87K - $157K *
Join a dynamic team to develop and enhance clinical systems, ensuring compliance with NIH standards. Collaborate with cross-functional teams to troubleshoot and implement solutions that improve health...
1 week ago
Senior Analyst, Decision Science (Client Marketing)
$105K - $129K *
Elevate client engagement through data-driven insights! As a Senior Analyst, you'll analyze performance metrics, enhance marketing strategies, and drive client retention, ensuring impactful decisions...
2 weeks ago
Nurse Practitioner or Physician Assistant
$90K - $110K *
Elevate senior healthcare by providing compassionate primary care in skilled nursing and senior living facilities. Collaborate with teams to enhance wellness, manage chronic conditions, and ensure qua...
4 weeks ago
Governance, Risk and Compliance Lead
$132K - $156K *
Lead the charge in governance, risk, and compliance initiatives, driving process optimization and collaboration across teams. Utilize strategic thinking to manage projects, enhance training programs...
Yesterday
$135K - $150K *
Lead the charge in enhancing cybersecurity operations by managing incident response, mentoring SOC analysts, and developing processes to effectively identify and mitigate threats in a 24/7 Security Op...
Reposted 3 days ago
Emergency Medicine Nurse Practitioner or Physician Assistant
$110K - $130K *
Take ownership of patient care as an experienced emergency medicine provider, delivering high-quality medical services in a dynamic environment. Collaborate with a dedicated team to ensure optimal out...
1 week ago
Applications Analyst III 4|sight
$80K - $95K *
Drive customer success by installing and supporting advanced applications for financial institutions, ensuring seamless integration and training on check imaging solutions while collaborating with a d...
2 weeks ago
Applications Analyst III 4|sight
$80K - $95K *
Unlock potential by joining a dynamic team to implement and support advanced applications for financial institutions, ensuring seamless software installation and customer training in a hybrid work env...
2 weeks ago
$68K - $93K *
Join a dynamic team to enhance enterprise security solutions, investigate incidents, and ensure robust protection against threats. Collaborate across teams to deliver effective security services and m...
Today
$82K - $100K *
Join a team that's dedicated to enhancing business processes and IT solutions. As a Business Systems Analyst, you'll drive project timelines, analyze workflows, and ensure compliance while collaborati...
Today
$95K - $115K *
Pioneer the delivery of impactful product features by guiding Agile teams, prioritizing stakeholder needs, and translating complex requirements into actionable user stories. Drive collaboration and co...
3 days ago
Enterprise Sales Executive (AI Native)
$125K - $150K *
Accelerate your career by driving growth in healthcare sales. Leverage your expertise to build relationships with key accounts, navigate complex deals, and shape future services that impact the indust...
4 weeks ago
ERP Functional Business Analyst - Performance Budgeting (PB)
$89K - $156K *
Transform enterprise budgeting solutions by analyzing processes, defining requirements, and configuring applications. Collaborate with stakeholders to enhance financial planning and ensure successful...
Reposted 3 weeks ago
Inpatient Coding Specialist II (Remote)
$137K - $154K *
Advance the future of healthcare coding by accurately assigning ICD-10 codes and MS-DRGs for inpatient records. Collaborate with clinical teams to ensure compliance and optimize reimbursement while ma...
4 days ago
Director, Client Coding Integration
$97K - $145K *
Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...
Reposted 2 weeks ago
FT PMHNP- St. Joseph, MO- (5d/w)
$100K - $120K *
Shape the future of mental health care by providing clinical expertise in post-acute settings. Enjoy flexible scheduling, collaborate with interdisciplinary teams, and deliver comprehensive psychiatri...
3 weeks ago
Director Workforce Management-Service Experience
$131K - $197K *
Unlock strategic leadership in Workforce Management, optimizing resource planning across various channels to enhance service delivery and drive performance guarantees in a dynamic contact center envir...
Reposted 1 week ago
$124K - $171K *
Transform healthcare outcomes by leading large-scale lab diagnostics deals. Drive revenue growth and customer retention through strategic planning, relationship building, and effective execution in a...
1 week ago
Pharmacy Benefits Management (PBM) Underwriting, Senior Analyst
$46K - $122K *
Join a team that's redefining healthcare contracts by leveraging financial expertise and strategic negotiation skills to enhance client relationships and drive business success in a dynamic environmen...
6 days ago
Pharmacy Benefits Management (PBM) Underwriting, Senior Analyst
$46K - $122K *
Unlock potential by joining a strategic team that formulates pricing strategies and analyzes complex data modeling for financial profitability in a dynamic healthcare environment. Drive impactful clie...
Reposted 2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.