Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$95K - $115K *

Grow your career by driving revenue growth in the acute care market through new customer acquisition and account expansion. Manage the full sales lifecycle while collaborating with internal teams to d...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$153K - $207K *

Lead impactful initiatives in healthcare fraud analysis, driving data-driven solutions and collaborating with cross-functional teams to enhance Medicaid and Medicare outcomes while presenting findings...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$219K - $277K *

Elevate community oncology practices by driving growth and retention through strategic sales initiatives. Collaborate with cross-functional teams to enhance market presence and deliver tailored soluti...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Drive strategic initiatives by developing KPI frameworks and operational dashboards, analyzing performance data, and collaborating across teams to enhance business outcomes and support informed decisi...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Empower healthcare transformation by developing strategic initiatives that enhance operational efficiency and clinician productivity. Collaborate cross-functionally to drive impactful solutions and im...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential as a senior Epic Willow Analyst, leading pharmacy workflow configurations and supporting clinical applications in a dynamic healthcare environment. Collaborate with teams to opti...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$111K - $167K *

Empower your career by leading IT systems development, implementation, and maintenance. Oversee complex networks, ensure security, and drive automation, all while collaborating to enhance operational...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $185K *

Unlock insights at scale by transforming complex healthcare data into actionable analytics solutions. Collaborate with cross-functional teams to design and optimize data models, ensuring high-quality...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $200K *

Drive VA health systems integration by leading complex interoperability initiatives, ensuring seamless data flow across clinical and community care platforms to enhance Veteran care and operational ef...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Business Services

$102K - $190K *

Elevate change management processes by leading operational execution and quality assurance. Oversee complex change reviews, coach teams, and ensure compliance with governance standards while enhancing...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower data-driven decisions by designing and optimizing complex data pipelines. Collaborate with cross-functional teams to ensure scalable, high-quality data solutions that enhance analytics and rep...

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $170K *

Drive the evolution of Legal Operations analytics by building scalable data capabilities, modernizing reporting, integrating AI, and establishing predictive models to enhance decision-making and opera...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$182K - $250K *

Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$200K - $215K *

Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$72K - $100K *

Unlock potential by analyzing and interpreting data to drive business insights. Collaborate with cross-functional teams to manage statistical reporting, ensuring compliance and data quality while adap...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Join a team that analyzes credit policies and develops strategies to enhance lending effectiveness, utilizes data analytics for risk management, and collaborates with stakeholders to drive impactful d...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $210K *

Partner with us to drive innovative financial solutions in the healthcare sector. Leverage your Workday expertise for impactful implementations, collaborating closely with teams to transform operation...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $95K *

Engage with healthcare providers and patients to enhance clinical education, improve patient outcomes, and deliver essential support services. Collaborate with partners to strategize educational oppor...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Partner with us to enhance patient education and support healthcare providers, leveraging your clinical expertise to improve outcomes through effective training and collaboration within the healthcare...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape the future of data governance by leading a team to manage third-party data compliance, ensuring operational excellence and regulatory adherence while fostering collaboration across business unit...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $122K *

Shape the future of IT capabilities by leading requirements analysis and advisory support for a Department of War agency. Collaborate with stakeholders to deliver data-driven insights and enhance ente...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$96K - $111K *

Drive the administration and analysis of employee benefits programs, ensuring compliance and enhancing the associate experience. Collaborate with HR and external vendors to manage health, retirement...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Join a team that's shaping the future of innovation in cancer research by leading financial planning and commercialization efforts to support strategic growth and decision-making across an impactful o...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.