Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$119K - $145K *

Advance supply chain efficiency by optimizing operations, collaborating cross-functionally, and implementing innovative solutions. Engage with stakeholders to analyze performance metrics and support k...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$156K *

Empower residents by delivering essential dental care in long-term facilities. Enjoy flexible scheduling, clinical autonomy, and a supportive environment while earning competitive pay and benefiting f...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $192K *

Join a team that's poised to lead integrated IT audits while managing client relationships and project execution. Contribute to growth initiatives, talent development, and business solutions for Risk...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $245K *

Advance clinical excellence by leading hematology studies, ensuring data integrity and patient safety. Collaborate with cross-functional teams to design and execute clinical programs, driving innovati...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$250K - $325K *

Unlock the potential of age-friendly health systems by providing strategic clinical leadership and guidance. Collaborate with health systems to implement the 4Ms framework, driving improvements in car...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$138K - $162K *

Elevate your career by leading a dynamic team focused on optimizing Epic Cadence scheduling and reporting solutions. Drive operational excellence through collaboration, strategic planning, and innovat...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$260K *

Transform sales opportunities in life sciences by leveraging relationships to guide complex deals from conception to closure, while collaborating across teams to shape innovative solutions that addres...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower client success by leading technical implementations, ensuring data accuracy, and resolving complex challenges. Collaborate with cross-functional teams to enhance workflows and drive continuous...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Unlock your potential as a Senior Financial Analyst, driving financial insights and models to support growth. Collaborate across teams to enhance forecasting accuracy and optimize performance, playing...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$122K - $212K *

Lead the strategy and governance of internal and external reporting, financial models, and executive insights. Drive automation and analytics to enhance business performance while ensuring compliance...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$89K - $105K *

Deliver compelling marketing and policy content that enhances brand voice and reputation. Collaborate with teams to translate complex topics into clear narratives, ensuring high-quality, timely materi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$300K - $383K *

Lead and innovate within a dynamic health division, overseeing research projects and driving strategic initiatives to enhance organizational performance and impact in health policy and services...

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Unlock information security excellence by identifying risks and implementing cutting-edge solutions. Lead security initiatives while ensuring compliance with regulations and safeguarding critical data...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Elevate financial accuracy and compliance by overseeing accounting processes, preparing statements, and collaborating across teams to support decision-making and policy development...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Champion innovation by leading AI initiatives across the Insurance portfolio. Oversee the full lifecycle of AI solutions, driving strategy and collaboration with multidisciplinary teams to enhance cap...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$71K - $90K *

Optimize pricing strategies and underwriting analytics for value-based care partnerships, collaborating with cross-functional teams to translate data into actionable insights and support growth initia...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Drive impactful sustainability strategies by analyzing data and supporting ESG reporting for real estate clients. Collaborate with multidisciplinary teams to enhance building performance and meet evol...

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$201K - $251K *

Transform workforce intelligence by leading People Analytics, establishing data governance, and driving strategic decision-making in a high-growth environment. Collaborate across functions to enhance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Champion data-driven pricing strategies and optimize dynamic pricing systems to support deal integrity and sales success, ensuring seamless pricing operations across platforms and providing expert quo...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion AI deployment by designing and implementing innovative solutions across multiple platforms. Collaborate with teams to enhance customer experiences while ensuring data governance and security...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Empower medical initiatives by leading project teams, providing strategic guidance, and ensuring compliance with regulatory standards while fostering high-performing teams in a dynamic environment...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $115K *

Join a team that's dedicated to safeguarding employee health by leading our industrial hygiene program, assessing risks, and implementing effective safety measures in manufacturing and laboratory envi...

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$104K *

Empower patients to achieve their rehabilitation goals as you evaluate, plan, and administer personalized treatment, while actively collaborating with a clinical team in a supportive environment dedic...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$77K - $102K *

Lead the charge in delivering robust financial analysis for cutting-edge autonomous undersea vehicle programs, ensuring accurate cost visibility and forecasting as they scale from development to produ...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Pioneer community engagement and business growth by building strategic partnerships in healthcare. Drive outreach initiatives, enhance referral networks, and represent the organization at local events...

Roslindale, MARemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.