Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$160K - $200K *

Accelerate growth in healthcare marketing by leading strategy and demand generation for a multi-brand portfolio, establishing brand presence, and driving engagement to position as an industry leader...

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Analyze complex investigations independently, develop risk-based strategies, and mentor staff while collaborating with regulatory partners to enhance compliance and protect market integrity...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$101K - $119K *

Transform the payments landscape by ensuring compliance and mitigating risk. As a key player, you'll review merchant applications, analyze transactions, and enhance fraud detection systems, all while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$150K - $180K *

Unlock impactful research and teaching in applied microeconomics, focusing on social policy areas like labor markets, education, and criminal justice. Join a distinguished team dedicated to integratin...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$79K - $127K *

Optimize member health outcomes by managing complex care plans, coordinating services, and advocating for quality, cost-effective healthcare. Collaborate with healthcare teams to assess needs and moni...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $246K *

Champion healthcare legal compliance and investigations, partnering with senior leadership to navigate complex regulatory landscapes. Utilize expertise in healthcare laws to ensure integrity while sup...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$153K - $210K *

Strategize and enhance data integrity across extensive systems, ensuring all operational data is accurate and reliable for key clinical and financial workflows while enabling self-serve analytics for...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape the future of trading and analytics by driving initiatives that enhance our product lifecycle. Collaborate closely with partners while ensuring client needs are met through detailed problem-solv...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$75K - $90K *

Lead the charge in enhancing integration processes by analyzing, documenting, and supporting seamless data exchanges with external ATS partners, driving efforts towards scalability and efficiency acro...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$130K - $145K *

Lead and advance quality operations in healthcare audits, ensuring compliance, operational excellence, and alignment with global standards. Collaborate cross-functionally to drive process improvements...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Join a team that's dedicated to enhancing supplier quality through advanced planning and continuous monitoring. Collaborate cross-functionally to drive zero defects and ensure seamless production flow...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $287K *

Champion the design and execution of hematology/oncology clinical studies, leading cross-functional teams to ensure data integrity and impactful outcomes in a dynamic, science-driven environment...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $287K *

Lead the design and execution of hematology/oncology clinical studies, ensuring data integrity while collaborating with cross-functional teams. Drive impactful clinical strategies in a dynamic, scienc...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage with a dedicated Hospitalist team to deliver high-quality inpatient care. Enjoy a 7-on/7-off schedule that prioritizes work-life balance in a supportive environment, enhancing clinical skills w...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $213K *

Drive platform reliability as a hands-on Lead Full Stack Engineer. Ensure operational health through proactive error management, rigorous testing, and scalability efforts. Collaborate cross-functional...

Massachusetts, USRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$154K - $242K *

Join a team that's advancing oncology research through innovative tumor functional genomics and perturbation analytics. Lead scientific initiatives, collaborate with cross-functional teams, and drive...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$68K - $95K *

Unlock your potential as a Crisis Clinician, providing vital support to diverse populations in dynamic settings. Collaborate with community partners and enhance your diagnostic skills while making a m...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Lead environmental risk assessments for commercial real estate lending, ensuring compliance and guiding stakeholders. Collaborate with experts to enhance risk management policies and stay updated on r...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in assessing environmental risks for commercial real estate lending. Utilize your expertise to guide compliance, enhance risk management policies, and collaborate with stakeholders to...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the end-to-end recruiting process, enhancing strategies and partnerships across departments. Drive high-volume hiring with autonomy, ensuring a seamless candidate experience while collaborating c...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$72K - $130K *

Join a dedicated team to provide comprehensive care and support for patients with chronic conditions. Utilize your nursing expertise to triage, educate, and advocate for diverse patient populations in...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $116K *

Join a team that's dedicated to providing compassionate end-of-life care, empowering patients and families through quality support, education, and collaboration with a skilled care team to ensure comf...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$230K - $275K *

Manage comprehensive financial evaluations for utility-scale solar and BESS projects, delivering strategic insights and supporting investment decisions throughout project lifecycles while fostering cr...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$69K - $116K *

Champion compassionate care by managing patient needs and collaborating with families and healthcare teams to enhance quality of life in hospice settings. Drive impactful relationships and ensure dign...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$69K - $116K *

Join a team that's dedicated to providing compassionate care and support to patients and families in hospice settings. This role involves building relationships, empowering caregivers, and collaborati...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.