Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that champions proactive advocacy within healthcare policy. Lead government affairs initiatives, engage with federal agencies, and strengthen strategic partnerships to ensure impactful rep...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$93K *

Contribute to impactful energy projects by analyzing data, researching trends, and collaborating with senior analysts to deliver innovative solutions for utility clients. Your expertise will drive suc...

2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Empower your career with senior-level expertise in data architecture and warehousing. Drive data integration and management, ensuring effective solutions for Occupational Environmental Health practice...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $151K *

Innovate your career by leading penetration testing services programs that enhance the security of medical devices and applications, ensuring safety and compliance through robust testing methodologies...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance quality management practices in a CLIA laboratory, ensuring compliance and audit readiness while collaborating across teams to maintain effective quality systems and support regulatory standar...

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $95K *

Develop innovative data-driven solutions to enhance math education through AI and machine learning. Collaborate with educators and researchers to analyze complex datasets, improve instructional tools...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$140K - $180K *

Unlock potential by leading client strategy and product initiatives, driving growth through market insights and cross-functional collaboration. Shape solutions that enhance client value and optimize H...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$119K - $134K *

Partner with us to enhance patient care by supporting primary care teams remotely. Collaborate with on-site providers to manage patient needs effectively, ensuring seamless communication and coordinat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$78K - $86K *

Engage with a diverse team to develop and implement personalized therapy plans, enhancing clients' independence and daily functioning through innovative and compassionate care, fostering meaningful re...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $115K *

Drive the administration of OneStream, supporting FP&A and Accounts Payable teams. Enhance reporting, manage data integrations, and collaborate with Finance and IT to optimize processes and improve ef...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate client relationships by leading Client Success teams to ensure operational excellence, proactive issue resolution, and strategic growth, while fostering collaboration across departments to enh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $138K *

Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by leading product vision and strategy, prioritizing development efforts, and collaborating with customers and teams to drive impactful solutions within a compassionate, high-performi...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $231K *

Lead the charge in product execution, driving growth and market penetration by collaborating with sales teams to develop strategies and equip them with tools for success. Enhance customer value throug...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic IT team as the Clinical Systems Specialist, bridging Clinical Operations and Data Science to support and automate clinical systems, enhance data pipelines, and streamline operations for...

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$247K - $357K *

Lead the charge in implementing an AI-driven Customer Engagement Management Platform, revolutionizing digital customer interactions across 45 countries. Drive strategic transformation initiatives whil...

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $120K *

Take ownership of critical operational pipelines as a Research Statistician, executing analyses and improving processes to ensure the SAT Suite runs smoothly. Collaborate with cross-functional teams t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$113K - $188K *

Transform data into insights by developing cutting-edge machine learning models. Collaborate with multidisciplinary teams to address complex business needs using advanced analytics, ensuring data-driv...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$120K - $130K *

Unlock potential by managing complex datasets to drive decisions across a fast-scaling energy planning function. Collaborate with cross-functional teams to ensure data integrity and operational effici...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $140K *

Drive the development of predictive analytics models to enhance digital assessment operations, collaborating across teams to optimize decision-making and reduce costs while supporting strategic goals...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$64K - $108K *

Deliver strategic financial insights and support decision-making through advanced analysis, forecasting, and budgeting. Collaborate with finance and business leaders to improve performance visibility...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Analyze and lead evaluations for human-services and public programs, creating frameworks and performance measures. Collaborate with stakeholders to translate findings into actionable insights, ensurin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$123K - $178K *

Join a dynamic team to drive impactful training initiatives in Market Access, ensuring alignment with strategic goals across Specialty Care and General Medicines. Leverage your expertise to enhance on...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K *

Elevate Medicaid partnerships by driving strategic sales initiatives, securing contracts, and fostering client relationships. Lead a team to achieve growth targets while navigating market dynamics and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.