Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$85K - $98K *

Join a dynamic team to evaluate and enhance the financial health of affordable housing organizations nationwide. Utilize advanced analytics and strategic insights to support sustainable growth and ris...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Join a dynamic team as you manage clinical research sites, ensuring compliance and quality throughout all study phases. Build strong relationships, oversee monitoring activities, and contribute to tea...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$162K - $224K *

Elevate healthcare solutions by driving business development in neurodegenerative disease pathways. Collaborate with health systems and stakeholders to identify needs, develop strategies, and create i...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $130K *

Lead the charge in advancing digital pathology through innovative image analysis and machine learning techniques, driving insights from complex datasets to enhance drug discovery and deepen understand...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $130K *

Elevate clinical operations by managing daily oversight, ensuring quality care, and fostering a safe environment. Lead teams in quality improvement and compliance while enhancing patient and employee...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $103K *

Advance your career by managing contracts and ensuring compliance while supporting order management and customer communications. Collaborate with teams to negotiate terms and optimize performance in a...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$81K - $210K *

Take ownership of patient care transitions by collaborating with interdisciplinary teams to ensure efficient, high-quality care and timely discharges, while navigating health system services and maint...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$70K - $92K *

Join a team that's poised to drive client engagement through innovative sales strategies. As a vital part of our Corporate Sales team, you'll identify opportunities and foster new business relationshi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $170K *

Drive your career with a leadership role in Clinical Systems Engineering, overseeing integration and interoperability of medical technologies. Collaborate across teams to enhance patient care through...

3 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$145K - $170K *

Lead the Clinical Systems Engineering function, driving integration and interoperability of medical technologies. Establish strategies, standards, and governance to enhance patient care through effect...

3 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Drive quality assurance initiatives by building scalable automation frameworks and developing automated tests for Windows UI and web applications, ensuring seamless integration with CI/CD pipelines an...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$210K - $250K *

Unlock potential by leading strategic M&A initiatives, from evaluation to execution. Collaborate with executive leadership and cross-functional teams to drive growth through acquisitions and integrati...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join our team to enhance third-party risk management, ensuring vendors meet cybersecurity and compliance standards. Collaborate across departments to assess risks, support audits, and communicate effe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$97K - $146K *

Partner with us to provide clinical support for contrast media, delivering education and product expertise to healthcare professionals while collaborating with internal teams to enhance patient care a...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$92K - $138K *

Join us as a Clinical Application Specialist, leveraging your expertise in maternal-infant care to deliver training and support for digital healthcare solutions. Collaborate with teams to enhance clin...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Unlock potential by leading the design and optimization of enterprise workflows. Collaborate with cross-functional teams to enhance operational efficiency and drive data-driven decisions within a dyna...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $159K *

Drive privacy excellence by executing assessments and managing risks across products. Collaborate with Legal, Product, and Engineering to embed privacy by design and enhance frameworks that protect cu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Shape the future of executive recruitment by leading strategic sourcing, engaging high-level candidates, and collaborating with a dedicated team to uncover top talent. This role offers growth opportun...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that champions proactive advocacy within healthcare policy. Lead government affairs initiatives, engage with federal agencies, and strengthen strategic partnerships to ensure impactful rep...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$93K *

Contribute to impactful energy projects by analyzing data, researching trends, and collaborating with senior analysts to deliver innovative solutions for utility clients. Your expertise will drive suc...

2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Empower your career with senior-level expertise in data architecture and warehousing. Drive data integration and management, ensuring effective solutions for Occupational Environmental Health practice...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $151K *

Innovate your career by leading penetration testing services programs that enhance the security of medical devices and applications, ensuring safety and compliance through robust testing methodologies...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance quality management practices in a CLIA laboratory, ensuring compliance and audit readiness while collaborating across teams to maintain effective quality systems and support regulatory standar...

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $95K *

Develop innovative data-driven solutions to enhance math education through AI and machine learning. Collaborate with educators and researchers to analyze complex datasets, improve instructional tools...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$140K - $180K *

Unlock potential by leading client strategy and product initiatives, driving growth through market insights and cross-functional collaboration. Shape solutions that enhance client value and optimize H...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.