Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$169K - $213K *

Join a team that's dedicated to delivering data-driven investment insights. As a seasoned analyst, you'll independently research U.S. large-cap equities, generate actionable ideas, and collaborate wit...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$169K - $213K *

Pioneer in equity research by delivering data-driven investment insights, conducting in-depth analysis of U.S. large-cap stocks, and collaborating with advisors to shape strategic recommendations for...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Optimize client success by leading strategic relationships and enhancing revenue cycle performance. Drive measurable improvements, manage escalations, and ensure value realization across healthcare so...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$184K - $396K *

Lead our clinical strategy in the West Region, driving performance in cost, quality, and member experience through partnerships with healthcare providers. Collaborate with teams to enhance value-based...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $133K *

Support our cyber defense initiatives by leading incident response efforts, analyzing security events, and optimizing detection capabilities to enhance network security and protect sensitive data...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$109K - $273K *

Join a team that's shaping the future of pharmaceutical consulting by managing strategic projects, delivering impactful solutions, and leading talented teams to drive client success in a dynamic, hybr...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$167K - $191K *

Unlock potential by leading HEOR/RWE initiatives, collaborating with cross-functional teams to drive evidence generation and strategic insights that inform clinical practice and access in oncology, en...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $212K *

Bring your expertise to our Trade Surveillance team as you develop and enhance detection models to combat market abuse, ensuring integrity in trading partnerships and delivering precise, actionable in...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$112K *

Transform data insights into actionable strategies by designing and automating reporting solutions. Collaborate across teams to enhance compliance and risk management while driving efficiency through...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Transform the future of biotherapeutics by designing and engineering multispecific biologics. Collaborate across teams, manage complex projects, and contribute innovative solutions to advance discover...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Transform data into actionable insights by owning the analytics pipeline from ingestion to visualization. Collaborate with cross-functional teams to create trusted models and metrics that empower deci...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitality & Recreation

$107K - $193K *

Join a team that's dedicated to comprehensive patient care, overseeing treatment plans and coordinating with specialists. Elevate your career by managing acute and chronic illnesses while providing su...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $120K *

Elevate your career by leading the administration and compliance of retirement programs. Oversee 401(k) and ESOP operations, manage vendor partnerships, and ensure regulatory adherence while enhancing...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$102K - $157K *

Unlock potential by driving new customer acquisition in healthcare. Engage C-suite leaders, champion innovative solutions, and lead complex sales cycles across AI and managed services to enhance patie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$166K - $250K *

Lead the charge in driving technical sales of innovative health solutions across payer and employer segments. Foster deep relationships and collaborate with teams to establish partnerships that genera...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$103K - $145K *

Transform product quality by leading risk management and compliance efforts throughout the design lifecycle. Inspire excellence in a collaborative environment, ensuring safety and performance standard...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$149K - $248K *

Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$117K - $201K *

Accelerate your career in Regulatory Affairs by driving FDA strategies for innovative cardiovascular medical devices. Collaborate with global teams to influence product approvals and enhance regulator...

Danvers, MARemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Transform the future of cardiovascular care as you oversee regulatory strategies and submissions for innovative digital health medical devices. Collaborate with global teams to ensure compliance and f...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Drive regulatory strategies and compliance for high-risk medical devices, ensuring successful market approval and navigating complex global regulations while collaborating with cross-functional teams...

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$113K - $133K *

Join a team dedicated to enhancing nursing excellence through innovative educational programs, mentoring, and evidence-based practices, ensuring regulatory compliance while fostering professional grow...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $278K *

Unlock strategic insights in oncology by leading competitive intelligence efforts. Drive team performance, anticipate market shifts, and deliver actionable recommendations to inform brand and portfoli...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$87K - $157K *

Unlock compliance excellence by managing auditing, monitoring, and reporting processes to ensure adherence to regulatory standards and enhance operational efficiency across contracts and collaboration...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.