Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$80K - $95K *

Help us enhance federal human capital operations through independent analysis, strategic recommendations, and effective program delivery. Collaborate on data-driven insights to improve efficiency and...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $136K *

Drive the success of research applications by leading analysis, design, and implementation efforts. Collaborate with diverse teams to optimize workflows and ensure effective technology solutions that...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$128K - $170K *

Empower executive leadership with strategic financial insights to drive growth initiatives. Collaborate on M&A, pricing, and R&D investments while delivering actionable recommendations in a fast-paced...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $94K *

Pioneer impactful scientific projects in healthcare consulting, leading teams in Rare Diseases and Value & Access. Drive business development, manage junior staff, and enhance client relationships whi...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $197K *

Unlock potential by leading the design and operationalization of advanced analytics and AI solutions to enhance healthcare operations and patient outcomes, while mentoring teams and influencing enterp...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join us to drive impactful data analysis that enhances product performance and operational effectiveness. Collaborate with cross-functional teams to uncover insights, develop KPIs, and translate compl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $135K *

Lead the charge in human services policy consulting to enhance operations and compliance for government agencies. Utilize expertise in federal regulations and stakeholder engagement to provide actiona...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Unlock potential by managing system design, build, and support for applications, ensuring optimal functionality and user satisfaction while collaborating across teams to enhance workflows and resolve...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $127K *

Unlock insights into medical cost trends by leveraging data analytics. Collaborate with cross-functional teams to develop strategic recommendations, track program outcomes, and present findings clearl...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $151K *

Unlock potential by collaborating with teams to analyze data needs, develop decision support systems, and implement innovative solutions. Lead projects, mentor colleagues, and ensure secure delivery o...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $119K *

Transform health data into insights by collaborating with researchers and programmers. Utilize SAS for data management and statistical analysis, contributing to impactful health policy research across...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $150K *

Unlock innovative solutions by collaborating with scientists and stakeholders to translate workflows into technology. This hands-on role combines business analysis and scientific platform administrati...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$132K - $278K *

Drive complex technology programs in healthcare, leading cross-functional teams to deliver impactful outcomes. Leverage industry expertise and client relationships to navigate challenges and optimize...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Transform healthcare by engineering seamless data integrations between complex EHR systems and our innovative platform. Empower clinicians with actionable insights to enhance patient care and outcomes...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $128K *

Shape data-driven strategies by developing and automating analytics solutions. Collaborate with cross-functional teams to enhance reporting capabilities and optimize operational performance in a dynam...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Drive impactful public health initiatives by leveraging data management and analytic expertise. Collaborate with scientists to enhance research quality and support CDC missions through effective data...

Massachusetts, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$175K - $200K *

Drive impactful change in healthcare consulting by leveraging your expertise in clinical operations and research administration. Collaborate with executive leaders to solve complex challenges and fost...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $231K *

Lead a team to optimize analytics capabilities, drive forecasting, and deliver AI-driven insights that enhance sales performance and support strategic business goals in a collaborative environment...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$142K - $186K *

Deliver trusted, governed product data by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure data quality and compliance, empowering stakeholders with self-servi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $130K *

Lead the charge in clinical trial monitoring, ensuring compliance and quality through oversight, guidance, and collaboration with cross-functional teams to enhance site performance and study execution...

Boston, MARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $135K *

Shape the future of clinical trials by leading site monitoring efforts, ensuring compliance, and fostering collaboration across teams. Drive quality and efficiency in trial execution while mentoring j...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Elevate clinical trial success by overseeing site monitoring, ensuring compliance, and providing leadership. Collaborate with cross-functional teams to address site issues, enhance recruitment, and ma...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Accelerate clinical trial success by leading site monitoring efforts, ensuring compliance, and providing expert guidance to the CRA team. Collaborate cross-functionally to resolve issues and enhance s...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead clinical trial monitoring efforts, ensuring compliance and quality. Collaborate with cross-functional teams to address site issues, manage budgets, and provide oversight. Drive successful study e...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.