Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$95K - $115K *

Drive excellence in risk coding management by leading a skilled team to enhance documentation accuracy and compliance for health centers, ensuring optimal patient care and risk adjustment outcomes in...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $205K *

Take ownership of complex PBM data integrations, ensuring accurate claims and eligibility processing while leading cross-functional teams and managing delivery timelines and risks...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$91K - $164K *

Lead the configuration and maintenance of Epic Client Systems, ensuring reliable access across clinical and operational environments. Collaborate with teams, troubleshoot issues, and mentor junior sta...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $145K *

Lead clinical research projects, ensuring compliance with regulations and timelines. Collaborate with teams and sponsors, manage study functions, and drive effective communication to achieve trial mil...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $127K *

Champion growth by driving enterprise sales in healthcare payors, leveraging SaaS solutions to enhance client experiences. Build relationships, negotiate contracts, and exceed quotas while collaborati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$138K - $238K *

Empower operational excellence by leading Payment Integrity initiatives, driving strategic alignment, and enhancing workforce effectiveness through data-driven insights and cross-functional collaborat...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Engage in comprehensive patient care for neurosurgical patients, providing evaluations, treatment plans, and surgical assistance while collaborating with healthcare professionals to ensure optimal out...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $120K *

Champion the development of high-quality program materials and deliverables, enhancing effectiveness in complex specialty markets. Collaborate with teams to ensure project success through strong manag...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion data-driven decision-making by transforming insights into actionable reports and dashboards. Collaborate with cross-functional teams to enhance performance, optimize strategies, and drive bus...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$67K - $118K *

Elevate business intelligence by designing and delivering impactful reporting solutions. Collaborate with teams to analyze data, enhance dashboards, and support decision-making processes, driving succ...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $90K *

Unlock potential by leading data analysis and storytelling efforts, ensuring insights meet client needs. Collaborate with teams to deliver actionable reports and maintain high-quality standards throug...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$89K - $95K *

Advance your career by providing skilled care to patients, educating families, and collaborating with healthcare teams to implement physician-directed plans of care. Your expertise will enhance patien...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $95K *

Deliver skilled care to patients, educating families and healthcare teams while adhering to physician orders and established care plans. Collaborate effectively to ensure high-quality patient outcomes...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $95K *

Empower patients by delivering skilled care and education, collaborating with healthcare teams to ensure adherence to physician orders and established care plans, while enhancing patient outcomes thro...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $95K *

Shape the future of patient care by delivering skilled services and education to patients and families, ensuring adherence to physician orders and care plans while collaborating with healthcare teams...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $140K *

Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$160K - $182K *

Drive strategic insights and analytics for the Neurology franchise, collaborating across functions to enhance launch readiness and field execution. Lead performance measurement and analytics to inform...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Join us to lead Oncology integrated solutions, collaborating across teams to design and implement strategic, client-focused approaches. Shape impactful proposals that drive growth and enhance patient...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$73K - $122K *

Lead the charge in ensuring fair market valuation of securities by analyzing pricing exceptions, conducting thorough research, and collaborating with the Pricing Committee to enhance valuation methodo...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $175K *

Optimize data analytics support for lab production operations by leading a dedicated team in a dynamic environment. Drive innovation, ensure compliance, and enhance operational effectiveness while mak...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $234K *

Grow your career with us as you support risk management practices, assess technology and cybersecurity risks, and enhance governance reporting in a dynamic, regulated environment. Collaborate cross-fu...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$98K - $147K *

Empower your career by leading an interdisciplinary team to deliver high-quality home health care. Oversee clinical services, ensure patient needs are met, and coordinate with healthcare professionals...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$68K - $106K *

Shape operational excellence in primary care by leading strategic initiatives, optimizing workflows, and enhancing patient experiences. Collaborate with clinical leaders to drive performance and ensur...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $143K *

Lead the charge in enhancing senior care by overseeing clinical services, ensuring compliance, and fostering a compassionate team environment. Drive quality improvement initiatives while maintaining o...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.