Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$100K - $161K *

Advance your career by coordinating clinical trial budgets and coverage analyses. Collaborate with stakeholders to ensure compliance and cost efficiency while mentoring junior staff and enhancing admi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Manage the nCino Commercial Loan Origination system roadmap by collaborating with key stakeholders to ensure alignment with business needs and maximizing value through effective product management in...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$90K - $115K *

Optimize campaign performance across key SEM channels, driving strategic improvements and leveraging data analysis to enhance profitability and efficiency while collaborating with cross-functional tea...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $160K *

Drive the development of LLM-based agents, ensuring robust production systems, effective evaluation, and seamless integration with company data while maintaining security and operational excellence ac...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Drive the future of AI & Analytics by leading client relationships, providing strategic guidance, and delivering innovative solutions. Leverage your expertise to enhance service delivery and ensure al...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $150K *

Join a team that's dedicated to advancing clinical research by managing complex studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficien...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$63K - $114K *

Shape the future of community health by coordinating seamless transitions for members. Collaborate with care teams to develop effective plans, educate families, and enhance service delivery, ensuring...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$109K - $164K *

Champion comprehensive patient care through clinical coordination, treatment supervision, and effective communication with patients and specialists. Drive departmental efficiency while managing acute...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $119K *

Drive impactful financial reporting for a rapidly growing organization, enhancing regulatory compliance through accurate, timely external and internal reports while collaborating across multiple funct...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $138K *

Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$146K - $190K *

Elevate provider success across the South region by spearheading strategic initiatives, optimizing team performance, and driving regional outcomes while ensuring adherence to national standards and lo...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $205K *

Join a dynamic team to lead AI agent deployments in healthcare. Leverage your software engineering expertise and client-facing skills to drive technical delivery, influence product development, and en...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $107K *

Drive financial integrity by managing complex accounting tasks, preparing reports, and influencing departmental strategy. Collaborate with teams to ensure compliance and accuracy while providing valua...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$84K - $107K *

Advance comprehensive home health services by assessing, planning, and delivering patient care directly in their residences: ensuring safety and effective communication within the healthcare team whil...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate your career by managing coding operations, ensuring accuracy and compliance across healthcare settings. Lead educational initiatives for staff, optimize workflows, and drive improvements in co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $187K *

Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $145K *

Drive clinical trial success by supporting study operations, ensuring compliance, and managing documentation from start to finish. Collaborate with cross-functional teams to maintain quality standards...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$134K - $164K *

Lead negotiations and manage contracts for innovative payment models, ensuring alignment with corporate strategy and financial objectives. Collaborate across departments to enhance healthcare reimburs...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$306K - $349K *

Join a team that's redefining AI applications by driving innovative research and collaboration across disciplines. You'll lead strategic initiatives, mentor talent, and engage with the research commun...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $175K *

Transform complex business challenges into actionable insights by leveraging advanced analytics and AI. Collaborate with commercial leaders to deliver data-driven solutions that enhance decision-makin...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$174K - $234K *

Shape the future of advanced analytics and AI, driving data-driven solutions across commercial, medical, and clinical operations. Collaborate cross-functionally to deliver insights, enhance decision-m...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$174K - $234K *

Shape the future of Hematology analytics by leading strategic insights and performance initiatives. Collaborate with cross-functional teams to enhance field execution and drive commercial success thro...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage and oversee marketing projects, ensuring timely delivery and effective communication across teams. Collaborate with Account Management to develop strategies and maintain project budgets while t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $130K *

Lead the charge in backlog management and agile ceremonies, translating stakeholder needs into prioritized tasks. Collaborate across squads to ensure delivery quality and stakeholder satisfaction whil...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead the Corporate FP&A function, overseeing forecast consolidation, monthly reporting, and financial analysis. Collaborate with finance and business partners to ensure accuracy and transparency in fi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.