Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$148K - $214K *

Optimize data governance and management for Market Access analytics, ensuring AI-readiness and quality across data assets. Collaborate with cross-functional teams to define standards and drive strateg...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $157K *

Join a dynamic team to develop and enhance clinical systems, ensuring compliance with NIH standards. Collaborate with cross-functional teams to troubleshoot and implement solutions that improve health...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$83K - $120K *

Join a team that's dedicated to improving health outcomes for underserved clients. As an RN, you'll conduct assessments, create care plans, and collaborate with a multidisciplinary team to provide ess...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Shape the future of paid social marketing by driving acquisition and revenue growth across multiple consumer brands. Collaborate to build creative strategies, manage performance, and optimize campaign...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's transforming life sciences through data-driven insights and strategic problem-solving. Collaborate with clients to tackle complex challenges, translating analytics into actionable r...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$105K - $129K *

Elevate client engagement through data-driven insights! As a Senior Analyst, you'll analyze performance metrics, enhance marketing strategies, and drive client retention, ensuring impactful decisions...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $162K *

Drive excellence in nursing education by designing and implementing innovative curricula, fostering continuous learning, and enhancing clinical skills through collaboration and evidence-based practice...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $105K *

Pioneer innovative solutions as you apply advanced analytics to evaluate energy strategies, manage projects, and lead research efforts for utility and government clients, driving sustainability and ef...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $105K *

Pioneer advanced analytics to drive data-driven insights for clients. Collaborate with teams to solve complex challenges in energy management, ensuring quality deliverables while managing projects eff...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$84K - $141K *

Reimagine your career with a role that drives IT solutions, enhances business processes, and supports technology training. Collaborate with teams to analyze data, streamline operations, and provide cr...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$81K - $122K *

Join a dynamic team to support M&A activities through financial analysis, market research, and transaction coordination. Develop expertise in valuation concepts and contribute to deal documentation an...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$97K - $105K *

Drive compassionate patient care as a Hospice RN Case Manager, guiding families through end-of-life journeys. Collaborate with interdisciplinary teams to deliver personalized care, ensuring comfort an...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $232K *

Lead and inspire teams in provider clinical operations, driving modernization initiatives through strategic consulting, process improvement, and technology integration to enhance healthcare delivery a...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $105K *

Shape the future of energy consulting by leveraging advanced analytics to deliver actionable insights and strategic guidance. Collaborate with clients and internal teams to solve complex challenges in...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Contribute to the advancement of cell and gene therapy by analyzing and interpreting critical data. Collaborate with cross-functional teams to ensure regulatory compliance and support product developm...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $196K *

Unlock potential by leading statistical design and analysis throughout the product lifecycle. Collaborate cross-functionally to define objectives and strategies, ensuring scientific integrity and effe...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $196K *

Engage with cross-functional teams to lead statistical design and analysis throughout the product lifecycle, ensuring scientific integrity and effective decision-making using diverse data sources...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$446K - $500K+*

Lead the charge in advancing nursing excellence and quality patient care across a multi-campus health system. Collaborate with executives to implement strategic initiatives that enhance operational ef...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $190K *

Transform the siRNA discovery landscape by leading a multidisciplinary team to drive innovative therapeutic candidates from concept to development, aligning strategic goals with core therapeutic areas...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $240K *

Elevate healthcare impact by building and scaling enterprise accounts in women's health. Own the sales cycle, engage stakeholders, and drive screening initiatives while collaborating across teams to e...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$54K - $108K *

Engage in client billing and revenue processes, ensuring accuracy and compliance. Collaborate with stakeholders to resolve issues and enhance operations through technology. Manage invoicing and financ...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $165K *

Partner with us to drive enterprise growth as you manage strategic relationships with healthcare systems. Your expertise will bridge teams and engage C-suite leaders, enhancing our portfolio value acr...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Drive strategic insights from payer and provider contract data to enhance patient access and safeguard portfolio value. Collaborate across teams to evaluate contracts, assess financial implications, a...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$114K - $165K *

Drive financial visibility and optimization in cloud spend by managing reporting, analyzing costs, and collaborating with stakeholders to enhance financial decision-making and efficiency across enterp...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $160K *

Explore transformative possibilities in computational biology by partnering with pharma allies to enhance drug discovery, utilizing AI tools to analyze complex datasets and drive impactful solutions i...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.