Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$218K - $249K *

Drive innovation by collaborating with cross-functional teams to develop AI-powered solutions that enhance customer experiences, leveraging advanced technologies and methodologies throughout the resea...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$124K - $280K *

Drive AI and ML solutions within healthcare, tackling complex challenges. Collaborate with diverse teams to deliver impactful results while enhancing operational efficiencies and clinical decision sup...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Legal & Accounting

$105K - $125K *

Transform coding quality and efficiency as a senior expert in radiology coding. Collaborate with cross-functional teams to enhance processes, provide guidance, and drive best practices, ensuring excep...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$71K - $97K *

Optimize laboratory operations by leveraging advanced technical skills and expertise. Perform complex assays, ensure quality control, and collaborate with healthcare professionals to deliver accurate...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $125K *

Shape the future of healthcare by ensuring compliance in Utilization Management and Quality Review. Leverage your clinical expertise to support benefit determinations and enhance process improvements...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$141K - $211K *

Transform clinical and revenue-cycle operations by leading cross-functional teams to optimize technology solutions, ensuring efficient charge capture and financial reporting while enhancing patient sa...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$142K - $195K *

Unlock potential by designing secure, enterprise-scale solutions that protect critical data and systems. Collaborate with stakeholders to assess threats, innovate security architecture, and enhance en...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$101K - $152K *

Empower the development of an enterprise compliance platform using Power Platform, combining strong technical skills and AI tools to drive architecture and enhance workflows, while ensuring security...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$240K - $275K *

Champion profitable coverage access with key government accounts and regional plans. Collaborate across teams to support Market Access objectives and enhance patient and provider experiences in this s...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Lead the charge in ensuring compliance and integrity within federal healthcare programs through rigorous investigations, data analysis, and collaboration with key stakeholders to produce actionable fi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$134K - $249K *

Empower organizational success by leveraging strategic actuarial analysis and tools. Lead a team while driving Medicare initiatives, managing financial assessments, and enhancing decision-making throu...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $110K *

Reimagine coding practices by delivering proactive education, ensuring compliance, and optimizing documentation across diverse pediatric specialties. Lead training for physicians to enhance accuracy a...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $282K *

Drive your career with a pivotal role leading AI-enabled evidence extraction for Neuroscience R&D. Collaborate across teams to develop scalable tools that enhance clinical decision-making and improve...

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$131K *

Advance health access and informatics by leading a dynamic team of providers, enhancing care delivery models, and championing EHR optimization for improved clinical outcomes across diverse patient nee...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$71K - $97K *

Contribute to patient care continuity as a telephonic Registered Nurse, guiding patients through post-acute services. Leverage your expertise in home health and hospice to ensure optimal care transiti...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $95K *

Join a team that's dedicated to providing compassionate care to patients. In this full-time weekend RN role, you'll administer skilled services, educate families, and collaborate with healthcare profe...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $196K *

Drive quality assurance for tax assignments and projects, ensuring compliance with tax laws while managing risks and providing guidance to junior staff in a collaborative environment focused on mainta...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Empower finance leadership with data-driven insights by building models, pipelines, and visualizations. Collaborate across systems to ensure data accuracy and support strategic decision-making in a dy...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$210K - $245K *

Lead and elevate epidemiological initiatives across R&D. Collaborate with teams on research and compliance to deliver insights that inform clinical strategies and regulatory submissions, enhancing pro...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $97K *

Empower data-driven decision-making across the College by coordinating analytics, reporting, and research initiatives, translating insights into actionable outcomes while ensuring data quality, compli...

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$132K - $174K *

Empower your career with hands-on technical leadership, driving innovation and excellence in healthcare systems. Lead a talented team, mentoring engineers while architecting scalable, secure solutions...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$96K - $144K *

Lead the charge in delivering exceptional customer service and technical support at assigned medical equipment sites, ensuring compliance with contracts and fostering strong client relationships throu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$88K - $149K *

Drive your career with a pivotal role in designing scalable data solutions, enhancing data accuracy, and fostering collaboration across teams to support operational decision-making and reporting excel...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Analyze clinical documentation and risk adjustment for healthcare providers, ensuring accurate representation of patient acuity. Collaborate with physicians to identify documentation opportunities and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $100K *

Join a team that's dedicated to enhancing intelligence efforts through expert analysis. You'll leverage analytics with a focus on counterintelligence to support federal objectives while collaborating...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.