Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$89K - $95K *

Join a team that's dedicated to enhancing patient care through effective training and compliance. You'll oversee documentation processes, collaborate with leadership, and ensure quality standards are...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$122K - $176K *

Unlock your potential by joining a dynamic team focused on developing multiscale computational models to drive innovative drug discovery and development, leveraging deep biological insights and advanc...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$77K - $129K *

Oversee technology-focused internal audits to enhance IT risk management, ensure SOX compliance, and strengthen control environments while guiding a team of analysts through comprehensive audits acros...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $145K *

Drive strategic growth by analyzing business opportunities and collaborating with C-suite executives. Manage cross-functional projects in a high-growth healthcare environment, ensuring confidentiality...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Lead the charge in integrating complex hospital data systems into Astra OS. Own end-to-end data pipelines, collaborate with customers, and design scalable solutions that enhance healthcare operations...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Analyze and evaluate network anomalies in a 24/7 SOC environment. Collaborate with analysts on cyber threats, develop incident reports, and enhance SOC processes. Build test labs for research and prov...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$119K - $186K *

Engage with health systems to drive strategic projects, enhance pharmacy solutions, and deliver impactful consulting services while mentoring and collaborating with clients to achieve transformative h...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to enhancing healthcare through precise coding. Leverage your expertise in outpatient coding and medical terminology while enjoying a fully remote role with flexible hours...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Engage in leading complex, cross-functional programs for healthcare clients. Drive strategic initiatives, manage risks, and enhance stakeholder communication while delivering impactful results in a dy...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $130K *

Unlock potential by driving data analysis and interpreting clinical trial results. Collaborate with stakeholders, ensure statistical integrity, and contribute to innovative methodologies in biostatist...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$68K - $103K *

Shape the future of revenue cycle management by driving process improvements and reducing denials. Collaborate with teams to analyze trends, implement best practices, and enhance client satisfaction t...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$109K - $164K *

Join a team that's dedicated to comprehensive patient care coordination, overseeing treatment plans, and managing chronic illnesses. Collaborate with patients and families while providing direction to...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $140K *

Elevate your career by analyzing and interpreting complex data to inform strategic decisions in Value-Based Care. Collaborate with cross-functional teams to enhance financial performance and drive imp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$163K - $245K *

Shape security architecture by designing robust frameworks across various tech domains. Collaborate with cross-functional teams to ensure comprehensive cybersecurity solutions aligned with business go...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $159K *

Inspire excellence in clinical documentation by leading a team of specialists, ensuring quality assurance, and fostering professional development. Collaborate with stakeholders to enhance operational...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $159K *

Lead the charge in enhancing clinical documentation integrity by supervising staff, conducting quality reviews, and fostering professional development. Collaborate with teams to implement effective st...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$77K - $121K *

Join a team that's redefining coding excellence by leading operational strategies, managing staff performance, and ensuring compliance in inpatient coding processes to enhance efficiency and quality a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $135K *

Drive the integration of AI and biological data science to generate actionable insights for drug discovery. Collaborate across teams, analyzing complex datasets while developing next-gen research tool...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Unlock your potential as a Revenue Compensation Analyst, where you'll design and manage compensation plans, analyze trends, and collaborate with teams to enhance sales efficiency. Bring your analytica...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $300K *

Optimize patient comfort and safety by delivering exceptional anesthesia care throughout surgical procedures and pain management, ensuring thorough evaluation and communication during preoperative ass...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$54K - $145K *

Lead the charge in enhancing Medicaid risk adjustment strategies, ensuring alignment between national objectives and local execution. Engage with senior leaders and stakeholders to drive performance...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $230K *

Shape global pipeline medical affairs strategy, driving differentiation and evidence development across oncology. Collaborate with cross-functional teams to ensure alignment and effective execution of...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate community health by leveraging your pharmacy expertise to ensure safe medication use, shape policies, and enhance patient outcomes in a supportive environment focused on professional growth an...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$111K - $222K *

Join a team that's transforming healthcare data into actionable insights. As a Senior Data Scientist, you'll drive advanced analytics solutions, collaborating across departments to enhance product str...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $222K *

Shape the future of healthcare analytics by transforming complex data into actionable insights. Collaborate with cross-functional teams to drive product strategy and optimize decision-making for a mem...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.