Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$142K - $195K *

Champion transformative enterprise architecture initiatives that align technology with business strategy, driving innovation and modernization across healthcare payer domains to enhance operational ef...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$106K - $147K *

Shape the future of healthcare technology by evaluating application portfolios to support strategic mergers and acquisitions. Collaborate with cross-functional teams to define integration strategies a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $125K *

Contribute to innovative pricing strategies by applying analytical skills and actuarial techniques. Collaborate across teams to develop and maintain pricing processes, ensuring effective communication...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $125K *

Optimize pricing strategies by leveraging analytical skills and collaborating cross-functionally to enhance rate adequacy monitoring. Develop innovative processes, support strategic initiatives, and c...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $127K *

Innovate with us to enhance data protection strategies, ensuring robust security and compliance across diverse platforms. Collaborate on complex projects, troubleshoot incidents, and drive improvement...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $181K *

Drive enterprise data governance and knowledge management strategies. Collaborate with cross-functional teams to enhance data quality, support compliance, and enable AI governance. Ensure strong data...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Drive multi-asset investment strategies by leveraging quantitative analytics, econometric forecasting, and portfolio construction techniques to enhance investment capabilities for diverse global asset...

1 month ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Engage in the dynamic Agile environment as a key player in defining and implementing business solutions. Collaborate across teams to deliver user-centric applications that address client needs and dri...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Deliver accurate performance analytics and business analysis in a fast-paced environment. Collaborate with IT on strategy, execute detailed data specifications, and mentor junior staff while providing...

1 month ago

  •   Less than 5 years exp.  •   Business Services

$88K - $140K *

Shape the future of public service by leading technology consulting projects that enhance operational efficiency and strategic goals for state and local agencies, ensuring compliance and delivering im...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$208K - $250K *

Lead the charge in clinical development, overseeing trials and cross-functional teams to ensure high-quality data supports product strategy. Drive innovative research while ensuring compliance and fos...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $200K *

Transform the healthcare experience by managing medical needs for skilled nursing residents. Collaborate with staff, diagnose conditions, and promote health practices in a supportive environment focus...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $119K *

Shape provider partnerships to enhance access to high-quality, affordable care. Collaborate on contract negotiations, analyze financial data, and strengthen relationships to drive market growth and va...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join us to drive growth in the Life Sciences sector by leveraging real-world data solutions. This pivotal role requires consultative selling skills and a proven track record in building relationships...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower data-driven decisions by building scalable data models and analytics solutions. Collaborate with cross-functional teams to transform raw data into actionable insights, ensuring high-quality re...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $105K *

Engage with business units to translate needs into reports, ensuring successful project implementation and support while mentoring junior team members in a dynamic environment...

1 month ago

  •   Less than 5 years exp.  •   Business Services

$100K - $140K *

Lead groundbreaking real-world evidence studies to enhance oncology insights, utilizing advanced statistical methods and AI tools, while collaborating with pharmaceutical partners to drive strategic r...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Deliver robust solutions as a Business Systems Analyst, supporting marketing and client service initiatives within IT. Collaborate across teams, conduct thorough analysis, and ensure system integrity...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$198K - $297K *

Engage in a dynamic role that empowers team collaboration and drives results in a leading organization recognized for innovation and excellence in performance, fostering an environment of growth and p...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Champion innovative care management strategies to enhance member outcomes, reduce costs, and improve clinical performance. Lead a diverse team in a dynamic environment, ensuring compliance and fosteri...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $198K *

Join a dynamic team as you lead innovative clinical programs, enhancing care solutions across oncology and cardiovascular disease. Collaborate with stakeholders to improve member experiences and clini...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $270K *

Unlock potential by designing and deploying scalable AI systems that transform healthcare workflows. Collaborate with cross-functional teams to solve complex business challenges and drive measurable o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $145K *

Join a team that's driving strategic initiatives in Pharmacy Services Finance. Lead complex projects, partner with stakeholders, and mentor team members to achieve measurable business outcomes while n...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive enhancements in client reporting systems by managing layouts, workflows, and automations. Collaborate with teams and vendors to optimize reporting processes, ensuring accuracy and efficiency in...

1 month ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.