Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.
Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.
Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.
Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.
Sr. Technical Product Manager, AI & Analytics
$116K - $193K *
Lead the charge in defining and executing the product strategy for AI and analytics, driving innovation across pharmacy management platforms. Collaborate with cross-functional teams to deliver scalabl...
3 weeks ago
Principal Product Manager, Member Experience
$200K - $230K *
Champion a transformative member software experience, guiding strategy and design across the care journey. Leverage data and user insights to drive impactful solutions in a complex healthcare landscap...
1 week ago
Clinical Development Medical Director, Obesity/Cardiovascular
$274K - $371K *
Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...
Reposted 6 days ago
Program Manager - Federal Financial / Regulatory Service
$105K - $150K *
Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...
2 days ago
$75K - $158K *
Champion operational excellence by managing the Avantra platform for SAP, ensuring secure, efficient monitoring and automation across diverse environments while collaborating with cross-functional tea...
Reposted 1 week ago
Quality Assurance Engineer III
$95K - $115K *
Lead the charge in enhancing software quality and reliability through automation. Collaborate with cross-functional teams to troubleshoot complex issues while mentoring others to achieve excellence in...
4 weeks ago
Program Administration Director
$130K - $216K *
Transform program administration for a large federal services initiative, overseeing workforce planning, financial operations, and compliance. Collaborate with diverse teams to enhance operational eff...
1 week ago
$95K - $115K *
Empower our finance team by overseeing accounting operations, ensuring compliance, and enhancing financial reporting. Lead month-end close activities and mentor team members in a dynamic, multi-entity...
2 days ago
$86K - $118K *
Innovate content design strategies to enhance user experiences across digital platforms. Collaborate with cross-functional teams to simplify complex healthcare information, ensuring clarity and access...
4 days ago
Solutions Engineer, API Integration
$107K - $180K *
Join a team that's redefining API integration! Leverage your technical expertise to guide partners through the integration lifecycle, ensuring seamless onboarding and successful implementations while...
2 weeks ago
Senior Clinical Research Associate/Clinical Research Associate II - US Any Region - FSP
$95K - $115K *
Join a team that's dedicated to ensuring the quality and safety of clinical trials. As a Senior Clinical Research Associate, you'll manage site relationships, oversee monitoring activities, and contri...
6 days ago
Associate Medical Director (RadScience)
$110K - $130K *
Join a dynamic team to lead the creation of impactful scientific content, enhancing medical education and patient outcomes. Collaborate cross-functionally, mentor writers, and drive excellence in heal...
5 days ago
$73K - $100K *
Empower program success by managing daily operations and documentation for a key transformation initiative, coordinating across teams, maintaining accurate records, and supporting financial and admini...
Reposted 3 days ago
$80K - $95K *
Optimize reporting and automation by leveraging Power BI and Power Automate. Collaborate with business teams to create insightful dashboards and efficient workflows, enhancing data understanding and r...
3 days ago
Lead Product Manager - Provider Direct Connect
$126K - $173K *
Champion the development of Provider Direct Connect capabilities, driving product vision and strategy while collaborating with cross-functional teams to enhance provider engagement and deliver scalabl...
1 week ago
Director of Cyber Security Operations
$208K - $235K *
Engage in strategic leadership of cybersecurity operations, enhancing organization-wide security across cloud-native and hybrid infrastructures. Drive incident response, digital forensics, and risk-re...
3 weeks ago
Senior Customer Success Associate
$110K - $130K *
Join a team that's redefining customer success in cybersecurity, driving engagement, onboarding, and adoption through innovative solutions. This role combines communication, relationship management, a...
3 weeks ago
Senior Software Engineer - Full Stack, Angular, Java, AWS
$128K - $170K *
Advance your career by designing and delivering scalable software solutions. Collaborate with teams to address challenges while enhancing product quality and performance in the healthcare supply chain...
Reposted 3 weeks ago
Data and AI Solution Architect
$150K - $180K *
Lead the charge in designing and delivering advanced data and AI solutions, focusing on scalable architectures and integration of cutting-edge technologies to enhance enterprise client operations and...
3 weeks ago
Analyst I, Falcon Complete (Hybrid, San Antonio)
$85K - $120K *
Transform global security by leveraging your technical expertise to detect, respond, and remediate incidents in real-time. Collaborate with a dynamic team to enhance processes and deliver exceptional...
1 week ago
Senior / Global Regulatory Labeling Strategist
$125K - $150K *
Champion global labeling strategy for innovative therapies, leading complex initiatives from development to post-approval. Collaborate with cross-functional teams to ensure compliance and high-quality...
1 week ago
Higher Education Solution Strategist - Google Gemini
$71K - $107K *
Drive the strategic implementation of advanced AI solutions in Higher Education, engaging with CIOs and CTOs to enhance IT infrastructure and governance. Leverage expertise to deliver impactful presen...
3 weeks ago
$150K - $180K *
Join a team that's shaping global regulatory strategy for rare disease therapies. In this pivotal role, you'll lead submissions and agency interactions across the US, EU, UK, and Japan, driving execut...
3 weeks ago
Quarterly Planning and Operations Analyst
$75K - $90K *
Drive execution and optimization of analytics strategies, collaborating with diverse teams to enhance product development and operational performance using AI and data insights. Be a key partner in co...
Reposted 3 days ago
Associate Vice President, Clinical Services - Market Access Marketing
$180K - $220K *
Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...
Reposted 2 weeks ago
What types of $100,000+ jobs can I find in Kentucky?
Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.
Which Kentucky cities have professional job opportunities?
Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.
Do jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.
How can I find a high-paying job in Kentucky?
Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.