Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.
Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.
Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.
Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.
Head of Clinical Quality and Regulatory
$208K - $220K *
Drive enterprise leadership in clinical quality and regulatory readiness, ensuring consistent standards and governance across regions. Collaborate with stakeholders to translate quality insights into...
4 days ago
$90K - $110K *
Lead the charge in overseeing complex clinical trials, ensuring timely execution and adherence to budget. Drive collaboration across teams while maintaining high standards for project delivery and sta...
4 weeks ago
Senior Advisor, Clinical Science (remote)
$168K - $283K *
Lead the charge in advancing early-stage clinical trials for innovative Orexin-targeted therapies. Collaborate cross-functionally to shape scientific strategy, drive execution, and ensure high-quality...
2 weeks ago
Senior Advisor, Clinical Science (remote)
$153K - $268K *
Transform clinical science in late-stage trials for innovative sleep/wake therapies. Collaborate cross-functionally to ensure compliance, drive recruitment, and deliver high-quality results while shap...
2 weeks ago
$101K - $146K *
Unlock potential by leading payer contract negotiations to enhance relationships, optimize revenue, and ensure compliance with regulations, all while aligning with strategic priorities of the health s...
2 weeks ago
Vice President, Project Management
$150K - $170K *
Lead the charge in transformative project management, driving cross-functional teams to execute multichannel initiatives successfully. Cultivate client relationships, ensure project delivery on-time...
4 weeks ago
Director Field Clinical & Patient Screening Programs
$149K - $298K *
Lead strategic and operational initiatives for field clinical teams, ensuring compliance and effective trial support for TMVR programs while driving positive patient outcomes and team performance...
4 days ago
$86K - $138K *
Drive independent assessments of deployment readiness across workstreams, ensuring quality and compliance. Collaborate with teams to produce readiness evaluations and present findings to leadership, e...
Yesterday
Senior Associate, Strategy & Operations
$125K - $155K *
Champion strategic initiatives by connecting breakthrough chemistry with market opportunities. Collaborate across teams to drive government partnerships, proposals, and commercial growth, transforming...
1 week ago
Senior Director, Reimbursement (Oncology)
$227K - $313K *
Elevate your career by leading strategic reimbursement initiatives, optimizing revenue cycles, and collaborating with key stakeholders to enhance patient access and billing processes in a dynamic heal...
1 week ago
$100K - $120K *
Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...
1 week ago
Director, Enrollment Operations(Duals Special Needs Enrollment Experience Required)
$113K - $197K *
Drive optimal enrollment operations through strategic leadership, overseeing member lifecycle processes, compliance, and data integrity while managing vendor partnerships and operational transformatio...
4 weeks ago
Family Nurse Practitioner or Physician Assistant - Deaconess Henderson Orthopedics F-T 80 hrs./pay
$85K - $100K *
Join a team that's dedicated to providing exceptional orthopedic care. As a Family Nurse Practitioner or Physician Assistant, you'll play a vital role in patient management, collaborating with healthc...
1 week ago
Business Development Senior Director
$160K - $200K *
Partner with us to lead transformative business development initiatives in life sciences. Drive revenue through strategic engagement with pharma/biotech partners, managing the full sales cycle and ens...
Reposted 3 weeks ago
Online Clinical Support Specialist
$92K - $138K *
Unlock your potential by joining a dynamic team focused on delivering top-notch Ultrasound IT support. Collaborate with customers to resolve complex technical issues in a fast-paced environment, ensur...
Reposted 1 week ago
Associate Director, Product (Data)
$165K - $175K *
Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...
2 weeks ago
DIRECTOR, WORKFORCE DEVELOPMENT
$144K - $245K *
Lead the design and execution of workforce development programs, ensuring compliance and timely deliverables. Collaborate across teams and stakeholders to create scalable systems that enhance healthca...
3 weeks ago
Senior Manager Application Development
$106K - $284K *
Lead application development initiatives, ensuring quality standards in healthcare IT. Collaborate with diverse teams to define requirements and implement solutions that profoundly impact patient care...
Reposted 3 weeks ago
Senior Data Quality and Governance Training Analyst
$117K - $195K *
Champion the development and execution of data stewardship training programs to enhance organizational data quality and governance skills while collaborating with domain experts to address skill gaps...
1 month ago
Staff Data Engineer – Data Fabric Integration, Defense & Systems Data Fabric
$112K - $149K *
Drive innovation by building and maintaining data pipelines and governance policies in a hybrid cloud environment. Collaborate with a small team to ensure reliable data flow and access control, enhanc...
2 weeks ago
Engineer II, Data Analytics (Remote)
$100K - $145K *
Optimize data center financial operations, analyzing performance, driving cost savings, and supporting strategic initiatives while ensuring efficient management of the data center portfolio through ro...
3 weeks ago
$100K - $120K *
Join a team that's dedicated to enhancing ERP solutions for colleges and universities. As a consultant, you'll collaborate on Ellucian Banner implementations, ensuring client needs are met within scop...
2 days ago
Senior Marketing Operations Analyst
$106K - $141K *
Join a team that's building an AI-ready data foundation for marketing and GTM. You'll design, govern, and analyze data models, ensuring reliable insights for strategic decision-making across the organ...
5 days ago
$92K - $154K *
Drive your career by developing integrated power conversion solutions for diverse industries. Leverage your technical expertise to create innovative applications and enhance business opportunities in...
Reposted 2 weeks ago
Software Engineer - Data Platform (R37)
$105K - $202K *
Engineer robust data platforms by designing scalable pipelines and APIs that support AI-driven healthcare applications, ensuring high performance, security, and operational excellence in a collaborati...
2 weeks ago
What types of $100,000+ jobs can I find in Kentucky?
Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.
Which Kentucky cities have professional job opportunities?
Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.
Do jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.
How can I find a high-paying job in Kentucky?
Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.