Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$210K - $250K *

Deliver comprehensive case reviews and clinical guidance, ensuring regulatory compliance and optimal patient outcomes. Collaborate with healthcare teams across multiple states to enhance service quali...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$155K - $160K *

Shape the future of data solutions by designing scalable architectures that drive AI and analytics initiatives. Collaborate with cross-functional teams to implement innovative strategies that enhance...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Drive reputation management and consumer insights initiatives, enhancing brand trust and informing strategic decisions. Collaborate across teams to analyze data, identify trends, and improve consumer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$189K - $261K *

Inspire growth by shaping the Molecular Imaging strategy, building key partnerships, and enhancing access to advanced imaging solutions across national imaging centers in the U.S. Collaborate cross-fu...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $135K *

Join us to lead and enhance healthcare staffing operations, driving growth and performance through strategic recruitment, client management, and team leadership. Collaborate across departments to achi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$91K *

Join a dedicated team providing essential dental hygiene services in a secure environment. This role involves patient assessment, preventive care, and clinical documentation, ensuring high-quality ora...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Deliver innovative solutions by managing complex programs, ensuring seamless execution and coordination across multiple contracts while leveraging extensive IT expertise and leadership skills to drive...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $155K *

Unlock potential by leading strategic partnerships in Creative Software Licensing. Drive growth through innovative deals, build relationships with developers, and shape the future of digital tools for...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Lead the charge in managing complex projects within the pharmaceutical and biotech sectors, ensuring successful execution and delivery while mentoring teams and collaborating with stakeholders to achi...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $95K *

Transform data into actionable insights by developing predictive models and automating workflows. Collaborate in a dynamic environment to enhance decision-making and operational efficiency using advan...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$182K - $216K *

Drive operational excellence by leading a 150+ member team, optimizing workflows, and enhancing member experiences through strategic program development and data-driven insights...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $100K *

Champion compliance excellence by reviewing retail communications to ensure adherence to regulations and firm policies. Collaborate with teams to maintain high standards and support organizational goa...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $100K *

Optimize revenue growth by driving GTM excellence and data-driven insights. Collaborate across Sales, Customer Success, and Finance to establish streamlined operations and enhance performance reportin...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$82K - $172K *

Design and implement innovative AI solutions, guiding pilot programs from conception to execution while collaborating across teams to enhance system capabilities and performance in a dynamic environme...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Empower healthcare partnerships by leading B2B marketing strategies, driving practitioner engagement, and optimizing conversion funnels. Collaborate cross-functionally to translate complex science int...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $158K *

Unlock your potential as you design enterprise-level data solutions that drive strategic decision-making. Lead complex data architectures, optimize reporting, and mentor fellow experts to enhance orga...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join a team that's dedicated to enhancing healthcare technology by developing and maintaining our Electronic Health Record platform using Ruby. Collaborate in an agile environment to deliver impactful...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Explore opportunities to partner with engineers and stakeholders, translating technical discussions into actionable deliverables while supporting CI/CD initiatives and repository governance with a foc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$176K - $243K *

Lead the charge in transforming oncology care by developing strategic partnerships and innovative programs that enhance patient-centered services and operational efficiency across healthcare systems...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $140K *

Transform your career by leveraging your RCM expertise to drive sales success. Collaborate with cross-functional teams to enhance customer experiences and optimize billing solutions for small to mediu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $126K *

Transform public safety operations by aligning technology solutions with customer needs. Collaborate in a dynamic team to implement an industry-leading SaaS platform, enhancing mission-critical workfl...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in operational excellence and strategic growth across multiple foster care locations, ensuring high-quality service delivery and regulatory compliance while fostering community partner...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$83K - $222K *

Drive innovation by delivering high-quality web applications and interactive dashboards. Collaborate with cross-functional teams to integrate AI capabilities and build resilient APIs in a fast-paced...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.