Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$110K - $130K *

Elevate your career by supporting clinical studies through scientific expertise, operational delivery, and compliance. Collaborate with cross-functional teams and stakeholders to ensure successful tri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $155K *

Shape the future of HR technology by leading strategy, governance, and optimization of HRIS. Drive operational excellence, enhance user experience, and ensure compliance while managing a high-performi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$129K - $177K *

Shape the future of observability by leading engineering initiatives, mentoring teams, and designing scalable logging solutions. Collaborate across disciplines to enhance system reliability and perfor...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$122K *

Champion clinical excellence by leading large teams, ensuring strategic alignment, and driving patient recruitment while mitigating risks in clinical operations for successful study execution...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $140K *

Lead transformative healthcare initiatives by fostering client relationships, driving impactful research, and developing high-performance teams to achieve strategic goals and business growth...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$70K - $115K *

Empower your career by joining a dynamic team focused on healthcare compliance auditing. Utilize your analytical skills to drive impactful audits and contribute to client deliverables while receiving...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Unlock potential by providing personalized primary care to seniors in their homes. Collaborate with interdisciplinary teams to enhance patient outcomes while managing chronic conditions and acute visi...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $140K *

Reimagine client success by managing relationships and ensuring seamless communication across teams. Drive operational excellence and enhance client satisfaction through proactive updates, coordinatio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Engage with senior stakeholders to enhance R&D efficiency in life sciences. Drive proposals, develop strategies, and ensure quality oversight while building networks to support business development an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $198K *

Champion enterprise-wide process improvement initiatives by leveraging Lean Six Sigma methodologies. Drive operational excellence and measurable outcomes through strategic planning, project management...

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$90K - $136K *

Join a team that's redefining customer experience by translating complex business needs into actionable technical requirements, ensuring seamless integration across platforms and delivering innovative...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$195K - $341K *

Empower healthcare delivery by leading clinical reviews, provider education, and quality improvement initiatives. Collaborate with teams to enhance member care standards and support compliance with re...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Transform Medicaid programs by managing initiatives, coordinating stakeholders, and driving quality improvements. Leverage your expertise to implement policies and enhance operational efficiency in a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$105K - $130K *

Analyze financial performance and drive insights to enhance profitability. Collaborate with cross-functional teams to develop budgets, forecasts, and reports, ensuring consistent financial processes a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$210K - $250K *

Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$119K - $145K *

Advance supply chain efficiency by optimizing operations, collaborating cross-functionally, and implementing innovative solutions. Engage with stakeholders to analyze performance metrics and support k...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $192K *

Join a team that's poised to lead integrated IT audits while managing client relationships and project execution. Contribute to growth initiatives, talent development, and business solutions for Risk...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $325K *

Unlock the potential of age-friendly health systems by providing strategic clinical leadership and guidance. Collaborate with health systems to implement the 4Ms framework, driving improvements in car...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Empower client success by leading technical implementations, ensuring data accuracy, and resolving complex challenges. Collaborate with cross-functional teams to enhance workflows and drive continuous...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Unlock your potential as a Senior Financial Analyst, driving financial insights and models to support growth. Collaborate across teams to enhance forecasting accuracy and optimize performance, playing...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$89K - $105K *

Deliver compelling marketing and policy content that enhances brand voice and reputation. Collaborate with teams to translate complex topics into clear narratives, ensuring high-quality, timely materi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$77K - $109K *

Join the charge in enhancing citywide GIS operations through technical expertise in data management, spatial analysis, and application development, ensuring efficient and innovative GIS solutions for...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead the charge in developing secure, enterprise-grade AI solutions, overseeing architecture and implementation while driving cross-functional collaboration to enhance AI capabilities and ensure best...

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$71K - $90K *

Optimize pricing strategies and underwriting analytics for value-based care partnerships, collaborating with cross-functional teams to translate data into actionable insights and support growth initia...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$201K - $251K *

Transform workforce intelligence by leading People Analytics, establishing data governance, and driving strategic decision-making in a high-growth environment. Collaborate across functions to enhance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.