Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
$149K - $248K *
Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...
1 week ago
Senior Financial Analyst, Corporate Development
$80K - $108K *
Join a dynamic team driving M&A success through financial modeling, business due diligence, and cross-functional collaboration. Elevate your skills while supporting strategic deal execution that impac...
Reposted 1 week ago
Head of Care Solutions, Employer and Payer
$166K - $250K *
Lead the charge in driving technical sales of innovative health solutions across payer and employer segments. Foster deep relationships and collaborate with teams to establish partnerships that genera...
4 weeks ago
$87K - $157K *
Unlock compliance excellence by managing auditing, monitoring, and reporting processes to ensure adherence to regulatory standards and enhance operational efficiency across contracts and collaboration...
3 weeks ago
Executive Director - Healthcare Foundation
$123K - $198K *
Lead strategic fundraising initiatives and operations for a major healthcare foundation. Collaborate with hospital leadership to drive a $200M capital campaign and enhance donor engagement, ensuring a...
2 weeks ago
$94K - $158K *
Join our team to ensure quality patient care within our facility's operations, collaborating with staff and physicians to promote effective patient procedures, compliance, and team management in a fas...
1 month ago
$94K - $158K *
Drive quality patient care by leading facility operations, managing staff, and ensuring compliance with healthcare regulations while supporting operational excellence and patient satisfaction in a fas...
1 month ago
$110K - $130K *
Champion data-driven decision-making by defining key business problems, analyzing metrics, and delivering actionable insights to drive outcomes across core business areas...
2 days ago
$140K - $175K *
Empower scientific innovation by collaborating within product pods to develop and evaluate real-world evidence agents. Drive impactful research and ensure scientific rigor while partnering with indust...
6 days ago
$110K - $125K *
Elevate your career as a Senior Recruiter, driving talent acquisition strategies across diverse roles. Collaborate with hiring managers to enhance recruitment processes and build strong candidate pipe...
6 days ago
$134K - $181K *
Unlock potential by leading advanced analytics initiatives that drive business impact. Collaborate with cross-functional teams to develop machine learning solutions, translating complex data into acti...
6 days ago
Scientist I / II, Liquid Chromatography (LC), tLNP Analytical R&D
$88K - $105K *
Design and optimize liquid chromatography methods to support tLNP programs. Collaborate with cross-functional teams to ensure robust analytical capabilities for mRNA-lipid nanoparticle therapeutics, e...
2 weeks ago
$73K - $98K *
Unlock data potential by designing and optimizing data pipelines, ensuring compliance and efficiency. Collaborate with teams to enhance data management systems and support agile development for impact...
5 days ago
Sr Director Analyst - AI Technology Economics
$172K - $202K *
Discover innovative insights into AI's economic impact. Leverage analytics and market dynamics to shape vital research while influencing industry leaders with cutting-edge strategies and actionable ad...
1 month ago
Medicaid Plan Pharmacy Director
$121K - $225K *
Champion pharmacy strategy and compliance within Medicaid health plans. Lead execution and enhance financial outcomes while collaborating with cross-functional teams to meet diverse needs of stakehold...
Reposted 2 weeks ago
Medicaid Plan Pharmacy Director
$121K - $225K *
Join a dynamic Medicaid health plan as a senior pharmacy leader, directing strategic initiatives, ensuring regulatory compliance, and enhancing member and provider experiences in a collaborative, matr...
Reposted 2 weeks ago
Physician Assistant or Acute Care Nurse Practitioner Thoracic Surgery, Full-time
$100K - $120K *
Champion patient care by leveraging clinical expertise to manage health outcomes, mentor students, and enhance educational systems. Collaborate with healthcare professionals to deliver comprehensive c...
2 weeks ago
$90K - $110K *
Transform data exchange efficiency by designing and maintaining IT integration solutions, ensuring seamless connections and operational integrity across systems. Leverage your technical expertise to r...
3 weeks ago
$90K - $110K *
Take ownership of designing, building, and maintaining critical IT system integrations, ensuring data flow and operational efficiency while troubleshooting complex issues and optimizing performance in...
3 weeks ago
$90K - $110K *
Engage in a collaborative environment as a Nurse Practitioner, driving patient-centered rehabilitation. Your expertise will enhance functional outcomes and independence through comprehensive treatment...
2 weeks ago
$90K - $110K *
Pioneer patient-centered rehabilitation by collaborating with a multidisciplinary team to develop and implement effective treatment plans, ensuring optimal functional outcomes and independence for div...
2 weeks ago
Registered Nurse (RN) - Ortho/Trauma/Tele/Med-Surg
$79K - $118K *
Transform patient care as an RN in a dynamic, multidisciplinary team, focusing on Trauma, Ortho, Tele, and Med-Surg. Experience a supportive environment that promotes advanced skills and professional...
3 weeks ago
Director, Integrated Insights & Strategy, Field & Account Strategy
$162K - $271K *
Elevate field and account strategy through data-driven insights and analytics. Collaborate with sales leadership to enhance executional excellence and drive impactful decision-making across the Specia...
Reposted 2 days ago
$84K - $126K *
Empower patients through tailored occupational therapy assessments and interventions, enhancing their functional abilities and daily living skills in home health settings while collaborating with heal...
5 days ago
$117K - $161K *
Empower our Quality Engineering operations by managing portfolio governance, financial planning, and resource allocation. Collaborate across teams to enhance transparency and execution, driving strate...
Reposted 1 week ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.