Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
Anesthesiologist - Elmhurst Hospital
$363K - $500K+*
Transform patient care by evaluating, monitoring, and supervising anesthesia delivery. Lead a dedicated Anesthesia Care Team, ensuring optimal safety and quality across diverse surgical specialties wh...
2 days ago
$90K - $110K *
Drive AI transformation by mapping current processes and designing future-state models across G&A functions. Collaborate with stakeholders to identify automation opportunities and enhance operational...
1 week ago
$90K - $110K *
Elevate business operations by mapping current processes and designing AI-enabled future models. Collaborate with cross-functional teams to identify automation opportunities and drive transformation i...
1 week ago
$104K - $143K *
Advance clinical risk management by identifying, assessing, and mitigating risks in patient care and operations. Collaborate with leaders to enhance safety and compliance, ensuring effective strategie...
2 weeks ago
Translational Medicine Scientist
$110K - $130K *
Unlock potential by joining a global team focused on clinical research compliance. You will negotiate and interpret informed consent for biospecimens, shaping the future of precision medicine and ensu...
Reposted 2 days ago
$88K - $110K *
Join us to enhance business systems through collaboration, analysis, and innovative solutions. Drive efficiency and scalability while supporting critical IT infrastructure and ensuring alignment with...
1 week ago
RN Clinical Documentation Informaticist - Remote (see full posting for eligible states)
$80K - $95K *
Advance clinical documentation accuracy by collaborating with healthcare teams to ensure comprehensive patient records, reflecting severity of illness and risk of mortality, while maintaining complian...
3 days ago
$160K - $190K *
Unlock potential by providing strategic legal counsel to cross-functional teams in the Oncology sector, navigating regulatory complexities and influencing business outcomes while fostering leadership...
1 week ago
$138K - $201K *
Architect cloud-based data solutions and drive enterprise data strategy. Leverage advanced analytics and modern data architectures to enhance operational efficiency and compliance in healthcare data m...
1 week ago
Principal Research Scientist II
$145K - $175K *
Transform the landscape of pharmacokinetics by leading a dynamic team, driving strategic initiatives, and fostering cross-functional collaborations to enhance drug discovery and development capabiliti...
4 weeks ago
$112K - $187K *
Empower patient outcomes through expert infusion management and direct care. Collaborate with interdisciplinary teams, oversee therapies, and ensure safe, effective treatment while maintaining complia...
3 weeks ago
$64K - $96K *
Join a team that's dedicated to enhancing patient care through effective coordination and support. Collaborate with multidisciplinary professionals to manage chronic illnesses and ensure smooth transi...
2 weeks ago
$64K - $96K *
Elevate patient care by coordinating multidisciplinary teams to support individuals with chronic illnesses. Drive effective communication and resource management to enhance patient outcomes and ensure...
2 weeks ago
$195K - $217K *
Drive client success by leading strategic initiatives and fostering strong relationships in healthcare technology. Leverage deep domain expertise to enhance outcomes and ensure effective use of soluti...
5 days ago
Strategy & Program Development Director
$137K - $248K *
Shape the future of associate engagement by leading strategic programs that align workforce needs with organizational priorities, fostering collaboration and driving impactful change across the enterp...
6 days ago
$88K - $121K *
Join a team that's redefining financial analytics by developing cutting-edge predictive models. Collaborate globally, analyze large datasets, and drive impactful solutions in the financial services in...
1 week ago
Medicaid Certification Consultant
$70K - $120K *
Lead transformative Medicaid initiatives by guiding project oversight, ensuring timely execution, and enhancing stakeholder engagement. Collaborate with teams to streamline operations and achieve stra...
5 days ago
Director, Enterprise Performance & Analytics
$125K - $150K *
Pioneer the development of our Enterprise Performance & Analytics strategy, leading initiatives in Business Intelligence and reporting to drive data-driven decision-making across the organization, whi...
Reposted 3 weeks ago
Sr Consultant, Business Analysis
$83K - $141K *
Transform complex data into actionable insights by leading analysis efforts, collaborating with stakeholders, and enhancing decision-making tools to drive operational effectiveness and business improv...
4 days ago
$100K - $165K *
Optimize data systems by designing and maintaining scalable solutions that enhance decision-making. Collaborate across teams, mentor junior engineers, and streamline data processes to ensure high-qual...
2 days ago
Registered Nurse - Informatics Program Manager
$80K - $95K *
Join us in shaping the future of healthcare as you lead informatics initiatives, ensuring seamless integration of technology and patient care across our network. Drive innovation and collaboration to...
3 days ago
$100K - $120K *
Unlock potential by collaborating across teams to drive data integrity and safety in oncology clinical studies while developing comprehensive medical review plans and managing project deliverables...
Reposted 3 weeks ago
$100K - $120K *
Help us modernize our data platform by designing and building robust data models and analytics solutions. Collaborate with analysts and stakeholders to transform complex data into actionable insights...
1 week ago
$110K - $130K *
Join a team that's dedicated to optimizing SAP SuccessFactors configuration and analytics. You'll be the go-to expert for Employee Central, Position Management, and Compensation, ensuring system integ...
1 week ago
Senior Strategy & Analytics Advisor, C&CE - Evernorth - Remote
$112K - $188K *
Transform customer experiences by leading strategic analytics initiatives that drive operational efficiency and enhance associate capabilities. Collaborate with leadership to develop insights and infl...
2 weeks ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.