Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
Registered Nurse (RN)- Oncology
$73K - $110K *
Advance patient care as a compassionate RN in an outpatient setting, utilizing evidence-based practices and collaborating with interdisciplinary teams to ensure optimal health outcomes and a safe, the...
3 weeks ago
Senior Business Analyst, Deal Economics & Analytics
$101K - $115K *
Champion strategic initiatives by leveraging analytical expertise to drive impactful decisions. Collaborate with cross-functional teams to enhance deal economics and analytics, ensuring alignment with...
2 weeks ago
Registered Nurse - Inpatient Case Manager
$74K - $130K *
Champion patient care by coordinating multidisciplinary teams to ensure efficient, quality outcomes. Leverage critical thinking to assess complex discharge needs and educate families, while fostering...
Reposted 1 week ago
Lead Business Consultant - Individual & Family Markets (IFM)
$92K - $167K *
Lead the charge in aligning regulatory filing activities for Individual and Family Markets, ensuring efficiency and compliance. Drive project management and support cross-functional teams in achieving...
3 days ago
Lead Business Consultant - Individual & Family Markets (IFM)
$92K - $167K *
Drive the alignment of regulatory filing activities in Individual and Family Markets, ensuring efficiency and consistency. Support the Qualified Health Plan management process while tracking milestone...
3 days ago
Director, CMS & HHS Business Development
$182K - $250K *
Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...
2 weeks ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...
2 weeks ago
$100K - $120K *
Join a team that analyzes credit policies and develops strategies to enhance lending effectiveness, utilizes data analytics for risk management, and collaborates with stakeholders to drive impactful d...
Reposted 1 week ago
$79K - $118K *
Transform patient care by leading assessments, discharge planning, and case management. Collaborate with healthcare teams to ensure smooth transitions and compliance with regulations, while enhancing...
2 weeks ago
Workday Healthcare Financial Implementation Consultant
$140K - $210K *
Partner with us to drive innovative financial solutions in the healthcare sector. Leverage your Workday expertise for impactful implementations, collaborating closely with teams to transform operation...
Reposted 3 days ago
$132K - $181K *
Champion data-driven solutions by leveraging advanced analytics and machine learning to solve complex business challenges. Collaborate with teams to transform raw data into actionable insights, drivin...
4 days ago
Director, Regulatory Affairs Business Development
$150K - $180K *
Transform regulatory business development by leading strategic assessments, identifying opportunities, and managing cross-functional teams to ensure compliance and mitigate risks in pharmaceutical tra...
2 weeks ago
$68K - $103K *
Empower mothers by providing in-home cognitive behavioral therapy and support. Collaborate with healthcare teams to assess needs, deliver treatment, and ensure effective communication, all while maint...
3 weeks ago
$68K - $103K *
Join a dedicated team providing in-home cognitive behavioral therapy to mothers, assessing needs and delivering support. Collaborate with professionals to enhance maternal mental health and ensure eff...
3 weeks ago
$90K - $110K *
Join a team that's dedicated to enhancing patient independence through collaborative rehabilitation. Utilize your expertise to assess, plan, and implement effective treatment strategies in a supportiv...
2 weeks ago
Segment Controllership Analyst
$105K - $158K *
Join a team that's dedicated to enhancing financial accuracy and operational excellence through technical accounting compliance, process simplification, and robust internal controls, ensuring precise...
2 weeks ago
Care Transitions Utilization RN
$85K - $95K *
Optimize patient care transitions by managing critical post-acute needs. Collaborate with healthcare teams to ensure safe discharges and reduce avoidable hospitalizations through effective telephonic...
5 days ago
$120K - $145K *
Innovate your career by leading systems engineering for drug/device combination products. Collaborate across teams to ensure patient-centric design, compliance, and risk management while fostering ext...
2 weeks ago
$170K - $210K *
Shape the future of data engineering by owning our core infrastructure and driving the technical direction of data platforms. Collaborate across teams to ensure best practices in data modeling, pipeli...
3 weeks ago
Senior Data Scientist I, Real World Evidence (RWE), Life Sciences R&D
$120K - $170K *
Drive innovation in oncology research by leading real-world evidence studies. Collaborate with pharma clients to transform complex data into actionable insights, utilizing advanced methodologies and A...
3 weeks ago
Senior Manager, Trial Surveillance & Analytics (Hybrid)
$130K - $155K *
Drive innovation in clinical trial surveillance by integrating data, analytics, and AI. As a Senior Manager, you'll lead end-to-end solutions, collaborating across teams to enhance patient safety and...
1 week ago
$80K - $95K *
Drive patient education and support by leveraging clinical expertise to enhance healthcare outcomes, collaborating with providers and caregivers, and delivering essential training and resources for ef...
1 week ago
$115K - $130K *
Transform the future of food intelligence by analyzing business processes, defining functional solutions, and collaborating with product teams to enhance menu strategy and customer outcomes in a dynam...
4 days ago
NURSE SURVEYOR (Health Facilities Surveillance Nurse)
$89K - $121K *
Advance your career by conducting compliance surveys of long-term care facilities. This role involves preparing documentation, providing technical assistance, and ensuring adherence to health regulati...
5 days ago
Senior/Staff Machine Learning Data Scientist
$150K - $180K *
Transform healthcare by developing and deploying advanced ML models that enhance real-world efficacy. Collaborate with clinical and engineering teams to enable data-driven decision-making and deliver...
Reposted 3 weeks ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.