Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.
Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.
Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.
Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.
Director, Clinical Pharmacology (Oncology)
$175K - $210K *
Lead the charge in Clinical Pharmacology, driving strategic drug development initiatives and managing cross-functional teams to achieve business objectives. Utilize your expertise to influence decisio...
1 week ago
Senior Coding Compliance Auditor - Inpatient
$76K - $131K *
Elevate healthcare compliance by leading detailed coding audits, mentoring auditors, and implementing action plans. Drive innovation and ensure adherence to standards while fostering a culture of cont...
2 weeks ago
Senior HCM Analytics & BI Developer
$105K - $231K *
Optimize enterprise analytics solutions to provide real-time insights and reporting for federal HR stakeholders, driving strategic decision-making and compliance in a fast-paced modernization initiati...
Reposted 1 week ago
$90K - $110K *
Champion AI integration within consulting teams, enhancing productivity and client outcomes through innovative tools and workflows. Collaborate with leadership to drive adoption and create scalable so...
1 week ago
$112K - $202K *
Shape the future of our product suite by managing the full lifecycle from ideation to launch. Collaborate with stakeholders and lead multiple projects to enhance application capabilities, ensuring ali...
Reposted yesterday
$112K - $202K *
Manage the full lifecycle of IT products, leading strategic planning and execution. Drive innovation through collaborative vision-setting with stakeholders, overseeing 3-5 major application projects y...
Reposted yesterday
$112K - $202K *
Deliver end-to-end product management for a suite of applications, leading strategic planning, development, and launch efforts. Collaborate with stakeholders to set priorities and ensure alignment on...
Reposted 2 days ago
$95K - $115K *
Lead the charge in enhancing clinical data quality and interoperability. Collaborate with clinical evaluators and product teams to drive improvements in healthcare data management and support quality...
Yesterday
$100K - $125K *
Advance your career as a Systems Engineer, enhancing our global IT infrastructure. Collaborate with a dynamic team to manage Windows servers, cloud technologies, and automation in a fast-paced environ...
Yesterday
Sales Strategy & Operations, Senior Analyst
$57K - $120K *
Drive operational excellence by supporting a multi-channel sales force, enhancing sales-enablement technology, and leveraging data for impactful decision-making to achieve company growth goals...
1 week ago
Thought Leader Liaison US Hematologic Oncology and Transplant Midwest
$146K - $243K *
Transform the landscape of hematologic oncology by engaging KOLs and healthcare professionals to enhance education and drive strategic initiatives while collaborating with cross-functional teams to su...
Reposted 1 month ago
$67K - $112K *
Transform complex data into actionable insights by developing predictive models and analytics solutions for financial services clients. Collaborate with stakeholders to drive business value through ad...
Reposted 2 weeks ago
Assistant Director, Global Service Delivery
$100K - $120K *
Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...
2 days ago
$110K - $130K *
Lead the charge in developing innovative drug delivery systems and medical devices. Collaborate across disciplines to optimize processes, conduct experiments, and ensure compliance while driving proje...
2 weeks ago
Behavioral Health Safety Nurse Clinical Specialist and Pathway Coordinator
$91K - $137K *
Elevate nursing education by driving innovative programs and training initiatives, enhancing clinical practice through mentorship and collaboration, while supporting organizational excellence and prof...
Reposted 1 week ago
Healthcare Provider Finance, Supply Chain, HCM Consultant - Senior Manager
$124K - $280K *
Elevate healthcare operations by leading finance, supply chain, and HCM transformations. As a Senior Manager, you'll drive strategic initiatives, enhance efficiency, and guide teams through complex pr...
6 days ago
$108K - $120K *
Shape the future of enterprise data solutions by building scalable ETL/ELT pipelines, designing robust data models, and contributing to our architecture strategy, while collaborating with stakeholders...
3 weeks ago
$109K - $144K *
Reimagine healthcare technology as an Application Analyst supporting Epic Professional Billing. Leverage your expertise in revenue cycle operations to optimize billing accuracy and enhance workflow ef...
4 weeks ago
$82K - $90K *
Join a team that's dedicated to enhancing audit quality by applying GAAP principles, supervising staff, and ensuring compliance with SEC regulations. You'll coordinate audits, prepare financial statem...
Yesterday
$145K - $175K *
Lead and optimize clinical study feasibility efforts, collaborating with cross-functional teams to enhance design strategy, site selection, and patient recruitment, ensuring timely and effective trial...
3 days ago
$80K - $95K *
Transform data management and decision support in research by collaborating with scientists to build visualizations, optimize workflows, and enhance data integration across platforms, driving efficien...
1 week ago
Director, Business Development (Healthcare)
$110K - $150K *
Unlock new business opportunities by strategically engaging with key stakeholders in the Healthcare and Commercial Real Estate sectors. Collaborate cross-functionally to drive targeted campaigns and e...
4 days ago
Senior Statistical Programmer Analyst - T
$136K - $239K *
Unlock your potential by leading statistical programming efforts in clinical trials. Collaborate with cross-functional teams to analyze and report clinical data, ensuring compliance with industry stan...
1 week ago
$112K - $202K *
Drive the full lifecycle management of IT products, overseeing strategic planning, development, and launch initiatives while leading cross-functional teams to achieve business objectives and optimize...
Reposted 2 days ago
Senior Associate, Government Programs Compliance and Regulatory
$80K - $95K *
Champion your career by supporting compliance and regulatory matters in Medicare Advantage and Medicaid programs. Conduct research, analyze data, and develop client deliverables while collaborating wi...
2 weeks ago
What types of $100,000+ jobs can I find in Illinois?
Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.
Are there high-paying jobs outside Chicago?
Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.
How can I find Illinois jobs that pay $100,000 or more?
Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.
Do Illinois job listings include remote or hybrid roles?
Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.