Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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$80K - $100K *

Drive innovative palliative care solutions for members with complex needs, providing compassionate, evidence-based support through telehealth. Collaborate with interdisciplinary teams to enhance patie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$242K - $403K *

Lead global companion diagnostics strategy, integrating diagnostic plans with clinical development and regulatory objectives. Drive execution across therapeutic programs, ensuring alignment with patie...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a pioneering team to build an AI-enabled care delivery platform, bridging clinical expertise and engineering to create safe, effective patient care solutions. Drive innovation from concept to pro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $350K *

Transform your career by leading a national body imaging service line, optimizing workflows, and enhancing clinical quality standards while mentoring a dedicated team of radiologists across multiple l...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$88K - $116K *

Oversee and enhance the Wound Care Program, managing operations, finances, and community outreach. Collaborate with healthcare teams to improve patient outcomes and ensure compliance with regulations...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$275K - $350K *

Transform cancer care by delivering high-quality, evidence-based oncology services via telehealth. Collaborate with multidisciplinary teams to enhance patient outcomes and develop innovative care mode...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$274K - $371K *

Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$217K - $294K *

Innovate the U.S. Cardiovascular & Metabolic Medical strategy, leading evidence generation and stakeholder engagement for chronic weight management. Collaborate cross-functionally to ensure launch rea...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Shape the future of healthcare delivery by leading operations in denials resolution and payment compliance. Drive performance, quality, and financial outcomes while building a high-performing team and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$69K - $119K *

Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Drive program delivery across multiple products, ensuring timely outcomes by managing risks, dependencies, and stakeholder priorities. Collaborate cross-functionally to maintain accurate project data...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Take ownership of IMP labeling processes, ensuring compliance with global regulations and quality standards while collaborating cross-functionally to support clinical trial timelines and enhance label...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$154K - $196K *

Unlock potential by leading strategic government programs, managing P&L, and driving operational excellence. Oversee contract delivery, mentor staff, and foster client relationships to ensure growth a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$274K - $371K *

Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $226K *

Optimize customer relationships and educational programs in Cardiac Rhythm Management and Electrophysiology. Collaborate with teams to enhance product adoption and training initiatives, ensuring high...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$223K - $313K *

Collaborate with a dedicated team of physicians to ensure high-quality inpatient care through clinical expertise, thorough reviews, and utilization management. Advance patient outcomes by utilizing st...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Transform provider engagement by leading peer-to-peer conversations and ensuring clinical governance. Leverage your medical expertise to enhance patient safety and optimize drug strategies while repre...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing patient safety through data analysis, audits, and collaboration across departments. Drive improvements in EHR software and support quality initiatives to ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $120K *

Transform patient care by delivering precise teleradiology interpretations across various shifts, utilizing AI tools to enhance workflow and maintain high-quality standards while collaborating with he...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K *

Transform virtual healthcare delivery by providing compassionate, patient-centered care across a range of clinical cases. Enjoy the flexibility of a remote schedule while collaborating with a dedicate...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$208K - $250K *

Support patient care by providing expertise in Diagnostic Radiology, ensuring quality and safety in imaging services, and collaborating with healthcare teams to enhance patient outcomes and operationa...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$92K - $138K *

Deliver clinical expertise and training support for XR products, enhancing customer experience and operational efficiency. Collaborate with sales and clinical teams to drive education initiatives and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$210K *

Shape the future of telemedicine by delivering compassionate, patient-centered care through virtual consultations. Join a dynamic team of board-certified physicians managing diverse clinical cases acr...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive sales strategy for Diagnostic Cardiology and Vital Signs Monitors in the Indiana, Ohio, and Kentucky territory. Collaborate with teams to enhance customer support and leverage market insights fo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.