Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Lead Project Planner (hydropower)
$87K - $145K *
Unlock project success by leading complex planning strategies and schedule management. Collaborate with cross-functional teams to drive execution, mitigate risks, and enhance performance while ensurin...
2 days ago
Technical Leader - EMF Engineer
$115K - $130K *
Unlock your potential by leading research on electric and magnetic fields (EMF) and RF exposure. Collaborate with utilities and stakeholders to develop solutions and technical guidance for emerging en...
4 days ago
$160K - $200K *
Join a team that's dedicated to establishing a robust Quality Management System, ensuring compliance and excellence in global clinical development and commercialization. Lead quality initiatives and f...
2 weeks ago
Staff Product Manager - Data Protection
$164K - $205K *
Unlock potential by driving the vision and execution of Data Security products, collaborating with cross-functional teams to enhance a cloud security platform that empowers innovation and business gro...
3 weeks ago
$110K - $130K *
Unlock potential by fostering client relationships and expanding service offerings, enhancing market presence in the Consumer, Retail, and Logistics domain through innovative solutions and collaborati...
Reposted 2 weeks ago
Senior Software Engineer II - Agentic SDLC
$170K - $185K *
Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...
3 days ago
Change Data Management Specialist
$83K - $101K *
Join a team that's dedicated to optimizing change management processes. Leverage your expertise in document releases and support engineering teams while utilizing tools like Jira and MSTeams to enhanc...
2 days ago
Stonehaven - Director of Ceded Reinsurance
$200K - $350K *
Unlock your potential as you structure and manage reinsurance programs, collaborating with cross-functional teams to ensure effective risk transfer and operational excellence in a dynamic environment...
1 week ago
$80K - $95K *
Elevate customer support excellence by leading a dynamic team across multiple channels. Drive operations, coach specialists, and ensure a seamless customer experience while managing escalations and op...
1 week ago
Principal, Technical Architect
$148K - $269K *
Unlock innovative solutions by leveraging technical expertise to support sales teams in aligning technology with customer needs during the full sales cycle. Collaborate closely to foster client relati...
Reposted 6 days ago
Director, Growth & Retention - Shopper
$225K - $275K *
Lead the charge in driving shopper growth, transforming casual users into engaged buyers through innovative acquisition and retention strategies while overseeing a dedicated team from day one...
3 weeks ago
$175K *
Shape the future of global telecommunications by leading strategy, architecture, and operations for voice and video infrastructure, ensuring reliable and cost-effective communication services aligned...
4 days ago
Service Line Leader - Environmental Restoration & Health
$180K - $200K *
Advance environmental restoration initiatives for federal clients by leading multidisciplinary teams, developing strategic growth plans, and ensuring compliance with regulatory standards while driving...
2 weeks ago
$125K - $175K *
Join a dynamic team to drive financial strategy and insights, ensuring sound decision-making across high-priority projects. Collaborate with leadership to optimize performance and support innovative p...
1 week ago
Managing Director - Digital Infrastructure, Investment Banking
$210K - $250K *
Lead growth initiatives in digital infrastructure investment banking, driving deal origination, client relationships, and team mentorship while ensuring exceptional service delivery and execution exce...
Reposted 3 weeks ago
Staff Technical Program Manager (R14286)
$120K - $145K *
Transform complex technical programs into clear, actionable plans that drive member value. Collaborate with cross-functional teams to enhance processes, improve information flow, and deliver high-impa...
Reposted 3 weeks ago
Senior Product Manager, Enterprise Creative Tools & Outbound Product
$184K - $194K *
Drive your career as a Senior Product Manager, shaping innovative retailer experiences and analytics solutions. Lead cross-functional teams to deliver impactful products that empower retailers to thri...
2 weeks ago
Vice President, Quality Assurance & Regulatory Affairs
$247K - $385K *
Join a team that's redefining operational excellence by leading quality assurance, compliance, and governance initiatives across segments, ensuring standards are met while fostering collaboration and...
4 weeks ago
Area Director, Electrophysiology & Structural Heart-South
$176K - $243K *
Accelerate progress at the forefront of cardiovascular innovation, leading a dynamic team to drive the adoption of advanced imaging solutions in the U.S. market, while fostering strategic partnerships...
Today
Director, Software Engineering - Motion Technology
$150K - $180K *
Drive the strategy and development of innovative motion technology solutions, overseeing globally distributed engineering teams to deliver high-quality software. Collaborate with stakeholders to align...
Yesterday
Medical Director, Occupational Health & Workers' Compensation Managed Care
$300K *
Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...
Reposted 1 week ago
Clinical Project Research Manager - EDS/RWE/NIS
$110K - $130K *
Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...
3 days ago
$176K - $259K *
Inspire high-performing sales teams while driving impactful solutions for mid-sized Public Sector organizations. Utilize coaching, strategic problem-solving, and cross-functional collaboration to fost...
Reposted 5 days ago
Manager - Construction Relations
$80K - $95K *
Champion contractor performance by leading training and compliance efforts, enhancing safety and quality in telecommunications construction. Collaborate across teams to mitigate risks and drive improv...
3 weeks ago
$110K - $130K *
Empower your career by leading a dynamic team of Client Success Managers, driving customer satisfaction and retention while collaborating cross-functionally to maximize value from our solutions and in...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.