Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Product Manager - Clinical Member Data
$86K - $138K *
Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...
1 week ago
Principal Product Manager, Outbound
$152K - $223K *
Drive strategic initiatives across teams to achieve measurable outcomes. Lead complex programs, establish governance, and ensure alignment with product and business priorities while managing risks and...
Reposted 5 days ago
Deputy Director, Partnerships & Technical Integration
$196K - $210K *
Partner with us to shape the future of semiconductor workforce development by aligning industry needs with educational strategies, fostering partnerships, and leading initiatives that ensure technical...
1 week ago
Principal Business Intelligence Lead, System Performance
$200K - $275K *
Elevate data strategy and reporting for the System Performance Organization, transforming complex robotics data into compelling narratives for executive stakeholders while fostering team growth and al...
Reposted yesterday
$110K - $125K *
Join a team that's driving innovation in billing and data platforms. As a Senior Product Owner, you'll lead agile delivery, manage complex features, and ensure high-quality releases while collaboratin...
3 weeks ago
Senior Director - Security Posture & Exposure Management
$159K - $257K *
Transform security posture by leading enterprise vulnerability management, prioritizing risks, and driving remediation efforts across diverse technology environments. Collaborate with teams to enhance...
5 days ago
Sr Professional Services Manager (Implementation Manager)
$100K - $125K *
Execute complex enterprise implementations, translating customer needs into actionable strategies. Leverage your expertise to connect teams and drive successful onboarding while enhancing customer sat...
Reposted 4 days ago
$91K - $121K *
Elevate the commercialization process across the product portfolio, enhancing efficiency and data integrity. Lead cross-functional collaboration, implement automation innovations, and drive strategic...
Reposted 2 weeks ago
Team Lead, Software Development
$110K - $130K *
Elevate team performance by leading a Scrum team in developing and modernizing enterprise SaaS applications. Guide technical decisions, mentor engineers, and foster collaboration across departments to...
2 weeks ago
$120K - $145K *
Join a team that's redefining product management by leading cross-product initiatives and shared services. Collaborate with diverse teams to drive innovation, enhance platform capabilities, and delive...
2 days ago
VP, Global Sales, Inventory & Operations Planning
$180K - $220K *
Lead the global SIOP process, ensuring synchronization across Sales, Marketing, and Supply Chain functions to optimize inventory and enhance operational efficiency for $1.2B in annual sales. Drive str...
4 days ago
Manager, Microsoft & Unified Communications
$115K - $150K *
Lead the charge in optimizing and securing Microsoft 365 & Unified Communications platforms. Collaborate with cross-functional teams to deliver innovative solutions that enhance organizational communi...
3 weeks ago
Director of Channel Partnership Development
$125K - $140K *
Engage with Private Equity firms to develop strategic partnerships, promoting supply chain services and driving revenue growth through effective channel management and collaboration with stakeholders...
2 days ago
$132K - $153K *
Join a team that's redefining care management by leading strategic initiatives in utilization and appeals processes. Drive high-quality, cost-effective care while ensuring compliance and fostering a c...
2 days ago
$125K - $150K *
Transform complex product concepts into intuitive user experiences across various platforms. Collaborate in a high-ownership role, focusing on enterprise design that meets diverse user needs while ens...
Reposted 1 week ago
Senior Design Manager - Core Experiences
$228K - $285K *
Shape the future of user experiences by leading design teams focused on AI-powered interactions. Collaborate across product and engineering to establish quality standards, foster innovation, and devel...
Reposted 3 weeks ago
Senior Technical Product Manager
$153K - $213K *
Champion the development of a key platform, driving strategy, success metrics, and technical depth while collaborating across teams to deliver impactful solutions that meet customer needs and enhance...
2 weeks ago
$130K - $160K *
Empower your career by leading cross-functional initiatives that define and execute product strategies. Cultivate senior talent while driving clarity in vision and achieving impactful results across d...
1 month ago
$96K - $128K *
Unlock potential by managing procurement processes, ensuring vendor compliance, and facilitating bid preparations. Collaborate with project teams to optimize purchasing strategies and maintain operati...
3 weeks ago
Digital Program Manager, Customer Success
$100K - $120K *
Champion a data-driven Customer Success program that enhances retention, proactively identifies risks, and efficiently engages a diverse customer base through innovative workflows and analytics. Lead...
Reposted today
Director - Pharma Meetings, Account and Operations
$95K - $123K *
Lead the charge in pharmaceutical meetings operations, driving client partnerships and operational excellence while navigating compliance. Shape processes and enhance stakeholder engagement to deliver...
Reposted 1 week ago
$80K - $120K *
Reimagine product marketing as you lead strategies that connect innovation to customer success, driving market adoption and value. Collaborate across teams to craft compelling messaging and shape the...
Reposted 1 month ago
$125K - $150K *
Drive high-value B2B paid media strategies and growth across multiple channels while leading a team of media professionals, ensuring client success and operational excellence in performance marketing...
Reposted 2 weeks ago
$80K - $95K *
Elevate project management effectiveness by providing advanced administrative support, ensuring adherence to policies, and enhancing team performance through training and reporting. Drive project succ...
1 week ago
Manufacturing Engineering Manager
$95K - $115K *
Unlock potential by leading a dynamic engineering team to enhance manufacturing processes. Collaborate across functions to drive continuous improvement in safety, quality, and productivity while foste...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.