Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Lead Project Manager (AI Initiatives) - Remote
$110K - $130K *
Champion the execution of AI initiatives across the enterprise by overseeing project governance, planning, and cross-functional coordination, driving effective delivery from concept to measurable outc...
Reposted yesterday
1741 - Director, Strategic Sourcing Facilities- Retail
$125K - $185K *
Join a team that's driving strategic sourcing excellence in Facilities for Retail accounts. Lead a dedicated team to deliver innovative solutions, manage supplier relationships, and ensure high-qualit...
1 week ago
Product Manager II- Marketplace
$130K - $171K *
Lead the charge in managing a diverse portfolio of SaaS products, driving user engagement and retention through strategic product development and cross-functional collaboration to enhance customer loy...
3 weeks ago
Growth Executive - North America
$120K - $160K *
Elevate business growth by driving strategic sales initiatives across key sectors. Leverage your network to build relationships and develop tailored solutions, while collaborating with partners to enh...
2 weeks ago
Enterprise MarTech Program Manager
$120K - $130K *
Manage enterprise-wide MarTech programs, aligning cross-functional teams to drive B2C marketing initiatives. Translate business priorities into actionable plans, ensuring effective collaboration and m...
1 week ago
Senior Developer, Business Systems
$102K - $142K *
Transform Salesforce systems by enhancing integrations and configurations. Collaborate with a dynamic team to support professional services and streamline project management, ensuring seamless operati...
3 weeks ago
Senior Director, Risk Management & Insurance (Remote)
$181K - $241K *
Take ownership of enterprise-wide risk management strategies, guiding executive leadership in navigating operational, financial, and construction risks. Collaborate across functions to enhance risk pr...
1 week ago
$64K - $162K *
Transform creative visions into reality by leading a talented design team, driving innovative strategies, and ensuring high-quality project execution across various media platforms while collaborating...
3 weeks ago
Project Delivery Project Manager
$80K - $95K *
Reimagine project delivery by overseeing capital initiatives, ensuring alignment with standards while managing budgets, schedules, and stakeholder communication for successful outcomes in healthcare c...
5 days ago
$120K - $150K *
Lead strategic financial initiatives, partnering with leaders to drive insights and improve decision-making. Oversee complex projects, enhance financial models, and leverage technology to optimize FP...
2 weeks ago
$200K *
Lead the charge in building and scaling AI Data Operations, transforming emerging opportunities into commercially viable solutions. Drive strategy, partnerships, and operational excellence to support...
2 weeks ago
Salesforce Consultant, Change Management
$94K - $266K *
Shape the future of organizational change management by leading strategic initiatives that enhance user adoption and drive successful digital transformations in collaboration with clients and teams...
Reposted 3 weeks ago
Global Product Owner Autonomous Coding
$143K - $196K *
Champion innovative solutions in healthcare coding by leading cross-functional teams, optimizing product strategies, and enhancing customer experiences through data-driven insights and agile methodolo...
3 weeks ago
Product Operations Manager, Launch Readiness & Tooling
$136K - $160K *
Advance the software delivery process by managing launches and releases, ensuring accuracy and efficiency through automation and collaboration with cross-functional teams. Design workflows and tools t...
1 week ago
Vice President & General Manager, Connected Solutions - South Florida
$160K - $200K *
Optimize operational excellence and client service as a senior leader overseeing a complex Connected Solutions hub, ensuring high standards in production, technical operations, and team performance fo...
2 days ago
Manager of Business Development
$100K - $120K *
Drive revenue growth by leading and developing a high-performing sales team. Manage strategic client accounts, foster relationships, and implement scalable sales processes for sustained success in a d...
Reposted 1 week ago
$160K - $220K *
Champion safety and environmental excellence by leading EHS strategies across manufacturing operations, ensuring compliance, reducing risks, and fostering a proactive culture of safety and sustainabil...
6 days ago
Sr. Director, Strategy & Execution
$160K - $200K *
Transform the future of go-to-market strategy by leading cross-functional teams, driving execution governance, and shaping long-range plans to achieve growth objectives in a dynamic, global environmen...
2 weeks ago
$110K - $130K *
Deliver strategic program management by coordinating activities, assessing risks, and ensuring stakeholder alignment. Leverage expertise to enhance business performance and drive compliance while guid...
3 days ago
Lead Director - Digital Engineering
$144K - $288K *
Lead the charge in transforming customer identity platforms, driving modernization and operational excellence while overseeing a multi-team engineering organization to enhance security and customer en...
3 days ago
$110K - $130K *
Lead the charge in driving AI initiatives for claims operations, collaborating with stakeholders to enhance efficiency and client service. Own the product backlog and ensure alignment with measurable...
Reposted 3 days ago
Director, Healthcare Consulting Services
$149K - $224K *
Lead the charge in transforming healthcare solutions by overseeing the entire implementation lifecycle, ensuring quality standards, and driving customer adoption through effective education and suppor...
3 weeks ago
Category Manager - Professional Services
$113K - $135K *
Innovate sourcing strategies and manage vendor relationships to optimize talent procurement services across various categories, ensuring alignment with business needs while enhancing cost efficiency a...
Reposted 2 weeks ago
$80K - $95K *
Execute project development and implementation, managing budgets, schedules, and vendor tasks while ensuring quality standards and fostering collaboration across teams and clients...
2 weeks ago
$98K - $147K *
Empower success by leading strategic programs that enhance clinical, financial, and operational outcomes. Collaborate with teams to optimize processes and ensure alignment with organizational goals, d...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.