Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$190K - $237K *

Optimize sourcing strategies and procurement processes for clinical operations, ensuring effective vendor management and governance across global clinical trials. Collaborate with cross-functional tea...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $280K *

Drive success by leading Guidewire development for insurance clients, overseeing technical design, configuration, and testing. Collaborate with stakeholders to enhance policy, claims, and billing oper...

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$124K - $280K *

Champion your career by leading Guidewire development for insurance clients. Drive technical design, coach teams, and ensure delivery excellence while transforming policy, claims, and billing operatio...

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $180K *

Innovate product management across a diverse SaaS portfolio, leading teams to enhance strategy and execution. Collaborate with executives to drive growth and operational excellence in global markets...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $105K *

Empower your career by leading the delivery of IT services to schools and clients. Manage teams, foster client relationships, and drive operational excellence in a dynamic environment with continuous...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Drive pricing strategy and analytics for power distribution products, ensuring competitive market positioning and margin protection. Collaborate cross-functionally to enhance quoting processes and del...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$220K - $340K *

Champion construction delivery excellence across global data center sites, managing GC performance and budgets of $25M+. Lead strategy, negotiate contracts, and represent construction risks to executi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$168K - $285K *

Shape the future of financial strategy by leading R&D finance, partnering with executives to drive investment decisions, optimize spending, and enhance forecasting accuracy in a dynamic, AI-driven env...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in product innovation by managing the full lifecycle from ideation to launch. Collaborate with cross-functional teams to align technical and business goals, ensuring successful product...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$96K - $144K *

Take ownership of contract management by drafting, negotiating, and administering agreements with key customers. Collaborate with cross-functional teams to ensure compliance and operational efficiency...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$69K - $115K *

Engage in dynamic project scheduling to optimize operations, mitigate risks, and ensure timely project execution. Collaborate with teams to maintain accurate schedules and drive project success throug...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Grow your career with a dynamic role overseeing commercial equipment projects. Coordinate all phases from design to installation, ensuring timely completion and budget adherence while leading a divers...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$86K - $124K *

Champion project success by leading SAP implementations, managing teams, and ensuring alignment with client needs. Drive agile methodologies, facilitate collaboration, and deliver innovative solutions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $210K *

Lead the charge in managing design and coordination of OFCI electrical systems for a hyperscale data center. Drive project success through strategic oversight, team leadership, and client engagement w...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$95K - $115K *

Shape the future of heavy highway and bridge projects by leading onsite engineering efforts, managing teams, and ensuring compliance with construction schedules and standards while fostering collabora...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $220K *

Engage with cross-functional leaders to elevate product strategy and execution. Drive innovation in product development, leveraging AI to enhance customer value and business performance across a diver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$148K - $245K *

Transform user experience across global retail and e-commerce platforms by leading a multidisciplinary team, driving design excellence, and integrating AI into innovative solutions that enhance custom...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$120K - $135K *

Shape the future of project management in global health by leading teams, ensuring timely delivery, and driving operational excellence across multiple projects while aligning with client and business...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$135K - $160K *

Transform marketing strategies across two distinct organizations, leading brand development, communications, and growth initiatives. This player-coach role requires both strategic oversight and hands...

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$160K - $200K *

Engage in strategic leadership to drive operational excellence and service delivery for global Digital Workplace Solutions. Lead teams, enhance client relationships, and optimize performance in a fast...

Pennsylvania, USRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$125K - $150K *

Shape the future of healthcare technology by leading product management efforts, driving strategy, and delivering innovative data insights solutions. Collaborate with cross-functional teams to enhance...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Advance product development by coordinating multi-project teams, managing market assessments, and fostering cross-department collaboration to ensure innovative solutions and timely deliverables in a f...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $306K *

Join a dynamic team to lead AML Managed Services, ensuring compliance and quality across complex engagements. Collaborate with cross-functional teams to design scalable solutions that mitigate financi...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$195K - $325K *

Shape the future of risk management by leading data, analytics, and automation strategies for Technology Risk and Compliance, ensuring effective risk mitigation and compliance across the organization...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.