Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$162K - $238K *

Design and optimize R&D operations to enhance organizational effectiveness through data-driven insights, collaboration, and governance. Partner cross-functionally to drive continuous improvement and e...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Develop strategic leadership for a team managing complex client portfolios, driving retention, growth, and client experience objectives while fostering strong relationships with stakeholders and ensur...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$236K - $369K *

Drive the delivery of a cloud SaaS platform by leading multiple engineering teams, ensuring cohesive execution and product vision. Collaborate with cross-functional partners to enhance customer suppor...

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$135K - $160K *

Transform the Data Solutions landscape by leading product strategy, driving API integrations, and enhancing partner capabilities to maximize G2 data's market impact and customer value through innovati...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Join a dynamic team where you'll bridge technology and customer needs, ensuring successful enterprise implementations and fostering client engagement. Drive product enhancements through feedback and c...

4 weeks ago

  •   5 - 7 years exp.  •   Transportation

$210K - $250K *

Partner with us to lead transformative HR initiatives in a dynamic professional services environment. Shape talent strategies, drive AI integration, and build a robust People Services practice that su...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Business Services

$110K - $115K *

Lead facilities management operations, ensuring safety, compliance, and financial performance while driving strategic initiatives and fostering collaboration between client and regional leadership...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $115K *

Advance facilities management operations by leading strategic initiatives, ensuring compliance, and driving financial performance. Collaborate with leadership to enhance service excellence and operati...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$155K - $160K *

Drive the data and AI strategy by collaborating with clients, shaping predictive roadmaps, and translating complex problems into actionable product development, enhancing customer-facing analytics and...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$70K - $117K *

Manage the performance and growth of a global network of Authorized Service Providers, ensuring compliance and service quality while driving revenue growth through data-driven decision-making and part...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $215K *

Launch impactful product initiatives by bridging engineering and design while driving user-centered solutions and leveraging AI tools for enhanced workflows in a high-growth environment...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$171K - $338K *

Empower organizations by leading AI-driven HR and IT transformations. As a Senior Manager, you'll oversee multiple projects, build client relationships, and drive practice growth while mentoring teams...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$171K - $338K *

Drive transformative AI solutions by leading client engagements, managing teams, and optimizing service delivery across HR and IT. Collaborate with senior stakeholders to enhance employee experiences...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $150K *

Lead the development and execution of innovative procurement strategies, managing the full source-to-pay process while driving cost savings and vendor performance across the organization. Collaborate...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$179K - $220K *

Unlock potential by leading the Lattice MCP server strategy and integrations that enhance performance data interoperability within popular AI tools and external platforms, driving customer engagement...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Business Services

$88K - $154K *

Optimize document management processes for a large-scale industrial project, ensuring accurate, secure, and accessible records throughout all project phases. Collaborate with multidisciplinary teams t...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$170K - $230K *

Join a team that's redefining creativity in healthcare. Lead innovative strategies, guide multidisciplinary teams, and shape impactful campaigns for pharmaceutical clients while ensuring regulatory co...

2 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Champion the proposal process by leading submissions, coordinating resources, and ensuring strategic alignment. Drive improvements in proposal development while fostering collaboration across teams to...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $162K *

Inspire growth by engaging C-level clients with strategic insights and innovative solutions. Drive impactful consultative sales from existing accounts, fostering comprehensive relationships that unloc...

4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$90K - $110K *

Lead the charge in delivering impactful events by overseeing registration operations and leveraging technology. Collaborate with teams to enhance attendee experiences and ensure seamless execution of...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead strategic initiatives in Outside Plant Broadband management, optimizing product performance, pricing, and inventory. Collaborate across teams to enhance sales enablement and vendor partnerships...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$112K - $135K *

Unlock innovative data solutions as a Lead Product Manager, driving user experience enhancements for patients and clinicians. Collaborate cross-functionally to optimize AI products, ensuring alignment...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Optimize construction processes by managing site operations, schedules, and safety plans. Collaborate with project teams to ensure quality and compliance in pharmaceutical and institutional projects...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$125K - $150K *

Oversee a portfolio of clinical studies, ensuring compliance and quality. Lead Project Managers in executing complex trials, driving operational efficiency and client satisfaction while leveraging you...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Join a dynamic team to drive integrated marketing strategies that enhance brand visibility and support business growth through innovative campaigns, digital activation, and thought leadership across m...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.