Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$110K - $130K *

Lead the technical implementation of Synapse products, ensuring high-quality solutions and customer satisfaction. Collaborate with project teams, manage infrastructure deployment, and integrate health...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive execution of complex technical initiatives, translating business vision into actionable programs. Collaborate with cross-functional teams to ensure alignment with company objectives and measurab...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $180K *

Optimize project execution by leading planning, monitoring, and stakeholder communication to ensure successful project delivery in the power delivery sector, while managing resources and adhering to q...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$190K - $210K *

Advance our real estate strategy by leading portfolio planning, workplace design, and data analysis. Collaborate with internal teams and external partners to optimize office spaces, enhance employee e...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$168K - $231K *

Drive transformation by partnering with cross-functional teams to design and implement effective product operations, ensuring alignment with strategic goals and enhancing organizational effectiveness...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join our dynamic Account Management Team to drive growth in the corporate occupier software market. Leverage your sales expertise to build lasting client relationships and uncover new opportunities wh...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$120K - $145K *

Lead strategic product initiatives in advanced surgical technologies, driving development and commercialization efforts. Collaborate with cross-functional teams to enhance orthopedic outcomes and proc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$401K - $500K+*

Join a team that's shaping the future of infrastructure engineering by leading efforts for cloud platforms, scaling developer experiences, and unlocking transformative AI solutions to enhance producti...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$185K - $344K *

Advance transformation initiatives by embedding adoption strategies from design to deployment. Collaborate with leaders to enhance readiness and implementation, ensuring sustainable outcomes that impr...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$112K - $179K *

Lead the charge in managing complex IT projects from concept to implementation, ensuring timely delivery and compliance with federal standards. Collaborate with stakeholders to drive project success i...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$210K - $250K *

Lead the charge in driving strategic medical initiatives across projects, providing expert guidance and oversight on clinical trials to ensure successful development of therapies in psychiatry...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$200K - $245K *

Pioneer data-driven engineering for our Autonomy Data Flywheel initiative, overseeing the entire lifecycle to enhance AI-driven operations. Collaborate with cross-functional teams to achieve quality a...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Transportation

$110K - $130K *

Join a team that's shaping innovative products by translating customer needs into actionable solutions. Collaborate with cross-functional teams to prioritize and deliver high-quality outcomes in a dyn...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$121K - $193K *

Lead the charge in driving EU MDR compliance initiatives by managing cross-functional programs, ensuring timely delivery of regulatory milestones while optimizing resources and stakeholder engagement...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Lead the charge in therapeutic area strategy and scientific innovation, overseeing discovery portfolios across biologics and small molecules. Drive sustainable pipeline generation and align discovery...

1 week ago

  •   11 - 15 years exp.  •   Transportation

$165K - $242K *

Drive product innovation and delivery by leading cross-functional teams, managing product backlogs, and aligning technology solutions with business goals. Foster collaboration and continuous improveme...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$114K - $151K *

Unlock potential by leading the HV overhead switchgear portfolio, driving product strategy, market development, and cross-functional collaboration to achieve profitable growth and enhance utility solu...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Elevate your career as a Project Manager leading multidisciplinary civil and water resources projects, managing budgets, scopes, and teams to deliver solutions that enhance communities and ensure proj...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $160K *

Champion the vision and strategy for AI-powered products, driving their roadmap and delivery while mentoring peers. Leverage AI tools to enhance decision-making and product lifecycle management, ensur...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Champion the optimization of business systems for Legal, Safety, and Environmental teams. Drive continuous improvement and support for Icertis and related applications, enhancing user experience and o...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $225K *

Lead the charge in transforming data, cloud, and AI architecture for private equity firms. Drive technology assessments, evaluate risks, and translate findings into strategic insights, while collabora...

Today

  •   8 - 10 years exp.  •   Business Services

$170K - $190K *

Oversee the technical planning and implementation of control systems, ensuring effective deployment and support for FRCS Petaluma. Lead project management efforts, maintain documentation, and provide...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$117K - $201K *

Optimize risk management programs by leading cross-functional teams, ensuring compliance, and driving process improvements. Collaborate with stakeholders to enhance operational efficiency and maintain...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Engineer the future of critical facility commissioning by leading project teams, managing schedules, and ensuring compliance with design and safety standards. Drive successful project execution throug...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $125K *

Join a team that's dedicated to enhancing the customer experience through strategic vendor management and operational excellence. Lead initiatives that drive performance, compliance, and continuous im...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.