Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$80K - $95K *

Lead the charge in enhancing quality systems across manufacturing plants. Collaborate with cross-functional teams to ensure compliance with ISO 9001, drive continuous improvement, and elevate overall...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $195K *

Engage in strategic business development, overseeing global projects and teams. Drive long-term planning, policy formation, and customer negotiations while fostering collaboration with senior manageme...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$113K - $125K *

Drive product strategy and outcomes in a senior role, focusing on educational equity and data-driven impact. Collaborate with cross-functional teams to shape product direction, prioritize initiatives...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$124K - $207K *

Lead and influence high-complexity projects, allocate resources, and drive innovation across the Global Business Unit while developing talent and strategic partnerships to achieve business goals effec...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Drive operational excellence by leading a global team to deliver high-quality wellbeing programs. Collaborate with stakeholders to ensure effective execution, maintain standards, and enhance participa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$173K - $255K *

Empower global expansion by leading customer operations strategy, managing complex programs, and driving continuous improvement across international markets. Collaborate with cross-functional teams to...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$85K - $95K *

Transform client relationships by leading strategic projects, ensuring quality and alignment across teams. Collaborate with stakeholders to drive success and meet client expectations while fostering g...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in shaping HR strategies that drive business success, cultivate high-performance cultures, and empower leaders across a diverse, collaborative team. Your expertise will be pivotal in t...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$140K - $175K *

Transform investment research by evaluating and integrating diverse datasets, enhancing AI-driven workflows, and driving strategic content initiatives to elevate platform value and user experience...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$115K - $168K *

Lead the charge in federal grant management for the 988 Suicide & Crisis Lifeline, overseeing compliance, budgeting, and operations. Collaborate across teams to ensure effective grant administration a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Transform construction oversight by managing EHRM infrastructure upgrades. Collaborate with contractors, ensure quality assurance, and maintain project schedules while providing expert guidance throug...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$200K - $300K *

Join a dynamic team to manage bank capital relationships, drive coverage strategies, and support capital formation initiatives. This role offers growth opportunities in a fast-paced environment, focus...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$183K - $228K *

Drive strategic financial insights as a key partner to the go-to-market teams, owning revenue forecasts and investment economics. Collaborate with leadership to shape long-term growth strategies and e...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $130K *

Support the financial planning and analysis for Executive Leadership, encompassing budgeting, forecasting, and reporting. Collaborate cross-functionally to drive profitability through data-driven insi...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$138K - $214K *

Optimize project outcomes by leading preconstruction efforts for large-scale Data Center initiatives. Drive team performance, manage budgets, and ensure exceptional client relationships while overseei...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Shape the future of healthcare by leading complex architectural and facility projects, ensuring optimal client service and regulatory compliance throughout all project phases while guiding multidiscip...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Technical Services

$160K - $180K *

Lead organizational capability by bridging strategy and execution across diverse hospitality operations. Drive scalable frameworks and change management to enhance performance and sustain innovation a...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$215K - $409K *

Join a dynamic team and lead the expansion of a national municipal utility advisory practice, shaping strategies, enhancing client solutions, and driving growth across utility sectors. Cultivate execu...

1 month ago

  •   11 - 15 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in managing complex engineering projects for national laboratories, ensuring compliance and financial accountability while fostering client relationships and mentoring teams to drive i...

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Transform your career by leading IT operations and team development, enhancing service delivery, and managing technology solutions for a dynamic workforce. Drive improvements and ensure seamless suppo...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Accelerate brand transformation by leading a dedicated creative team, ensuring high-quality visual and verbal expression across global campaigns and touchpoints to create memorable customer experience...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$105K - $149K *

Transform complex Consumer-Directed Health implementations for major employers. Lead strategy, execution, and client engagement while serving as a subject-matter expert to ensure operational excellenc...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Drive partnership success by leading infrastructure creation and optimization. Collaborate with stakeholders to develop tailored plans, ensuring timely implementation and ongoing enhancement of strate...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Engage in strategic partnership optimization by leading infrastructure creation, ensuring timely implementation, and fostering strong stakeholder relationships to drive successful partnership outcomes...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$113K - $188K *

Empower healthcare systems by leading advisory projects, managing teams, and delivering data-driven solutions. Collaborate with clients to enhance performance and build strong relationships while ensu...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.