Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$128K - $178K *

Lead the evolution of our CMS and AI web strategy, driving product vision and execution for public sector clients. Collaborate with cross-functional teams to deliver innovative, customer-focused solut...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$151K - $178K *

Shape the future of credit decisioning by leading a team focused on automating underwriting processes, enhancing portfolio analytics, and driving policy governance in a fast-paced fintech environment...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$134K - $179K *

Elevate your career by leading a dynamic design team in delivering innovative energy and infrastructure solutions for complex projects. Drive multidisciplinary collaboration, ensure design quality, an...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Champion the execution of pharmaceutical projects, ensuring timely delivery and compliance with GMP standards. Lead diverse teams and manage budgets for projects ranging from $500k to $20M, while main...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$187K - $257K *

Empower transformation initiatives by leading enterprise projects, managing stakeholder relationships, and driving strategic outcomes. Collaborate with diverse teams to define program strategies and e...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Engage with us to lead the proposal development lifecycle, ensuring compliance and quality in federal government submissions. Collaborate with diverse teams to drive success in a dynamic small busines...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$95K - $115K *

Unlock potential by leading product strategy and execution for interventional solutions. Drive growth, manage product lifecycles, and collaborate cross-functionally to deliver innovative, patient-cent...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $230K *

Grow your career with a leadership role overseeing global operations, focusing on strategy development, performance management, and cross-department collaboration to drive operational excellence and i...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Support project management excellence by leading PPM processes and tools. Collaborate with teams to enhance project execution, ensuring alignment with industry standards and organizational goals. Driv...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $180K *

Lead the charge in expanding and retaining enterprise client relationships, driving revenue growth and strategic account management across regions. Develop and mentor a high-performing account team to...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$178K - $294K *

Join a team that's redefining data engineering and analytics. Lead strategy, architecture, and execution of scalable data solutions while mentoring professionals and driving business outcomes through...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$102K - $149K *

Lead the charge in assessing and managing facility systems for diverse clients. Utilize your expertise in mechanical, electrical, and plumbing systems to deliver high-quality evaluations and recommend...

Yesterday

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Lead the charge in developing and enhancing data analytics products, driving innovation while collaborating across teams to deliver user-centric solutions that align business goals with technical feas...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $175K *

Join a team that's dedicated to driving strategic initiatives and operational excellence. As a key player, you'll enhance the CEO's vision through analytical problem-solving and effective project mana...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$140K - $175K *

Advance your career by supporting the CEO's strategy through analytical problem-solving, project management, and process improvements, ensuring smooth operations and high-quality outcomes across multi...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$181K - $291K *

Lead the charge in managing the full systems development lifecycle for enterprise applications, ensuring data quality and integrity while evolving best practices across healthcare operations and suppo...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$173K - $231K *

Shape the future of technology in education by leading strategic IT initiatives, enhancing service delivery, and fostering collaboration across teams to support student success and operational excelle...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Drive strategic initiatives by developing KPI frameworks and operational dashboards, analyzing performance data, and collaborating across teams to enhance business outcomes and support informed decisi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead and execute medical facility construction projects, ensuring compliance and successful delivery through effective team collaboration and project management...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$216K - $318K *

Champion the evolution of AI Platforms, leading a dynamic team to enhance AI integration and productivity. Drive strategic initiatives that empower engineers and elevate member experiences through inn...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Lead the charge in executing capital and improvement projects, enhancing plant performance through collaboration with teams and vendors. Drive reliability and efficiency in a dynamic heavy manufacturi...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Transform organizational change by leading enterprise-wide initiatives that enhance workforce capabilities and drive AI adoption. Collaborate with senior leaders to design impactful training programs...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Lead and manage design-build projects, ensuring timely completion within budget while meeting client objectives and contractual obligations. Oversee scope development, financial performance, and compl...

United StatesRemote

2 days ago

  •   15+ years exp.  •   Transportation

$150K - $180K *

Transform the future of revenue accounting by leading the integration of consumer revenue streams into a unified, automated process. Drive accuracy and efficiency while building a high-performing team...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.