Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$217K - $298K *

Lead the charge in shaping Root's platform and AI engineering strategy, overseeing critical infrastructure and driving operational excellence across teams to deliver intelligent products at scale...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $115K *

Transform your career by leading financial strategy and operations for innovative service lines. Collaborate with senior leaders to enhance profitability, oversee budgeting, and drive growth initiativ...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead a team that drives client success through strategic guidance, managing large-scale programs, and fostering strong relationships. Ensure exceptional delivery and compliance while identifying growt...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$125K - $169K *

Lead the charge in enhancing customer success initiatives by driving engagement, optimizing processes, and fostering strong relationships. Collaborate with cross-functional teams to ensure exceptional...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $200K *

Accelerate progress at regional Professional Services by leading teams, driving growth and quality in consulting engagements while fostering strategic partnerships and developing innovative service of...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$228K - $342K *

Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$131K - $196K *

Unlock potential by developing AI-driven applications and data pipelines. Collaborate with teams to enhance operational efficiency through innovative technical solutions, ensuring quality and scalabil...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$80K - $95K *

Join a team that's dedicated to delivering high-quality electrical projects. As a Project Manager, you'll oversee all phases from planning to completion, ensuring timely and budget-friendly execution...

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$150K - $180K *

Transform enterprise risk management by leading critical audits and enhancing controls. Maintain relationships with external auditors and foster compliance initiatives to mitigate risk across all oper...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $130K *

Drive project success by leveraging technical expertise and leadership skills. Collaborate with cross-functional teams to ensure timely delivery of milestones while fostering continuous improvement in...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$154K - $193K *

Drive AI transformation by building client relationships, leading engagements, and delivering results. Own the sales process from prospecting to execution, ensuring successful integration of AI soluti...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$96K - $120K *

Lead civil engineering projects, focusing on site development for data centers and large-scale industrial programs. Utilize your expertise in project management and local permitting to drive successfu...

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $170K *

Unlock potential by leading eDiscovery projects, managing client relationships, and overseeing data processing and review workflows. Drive innovative solutions in a dynamic environment while mentoring...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$122K *

Champion project success by leading interdisciplinary teams to deliver innovative solutions in the biotech and pharma sectors. Drive milestone achievement, manage budgets, and ensure compliance with p...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Partner with us to lead inpatient surgical services, ensuring quality care through strategic oversight, innovative practices, and collaborative leadership across multiple units while fostering a cultu...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$102K - $152K *

Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$220K - $290K *

Accelerate the development of autonomous systems by leading systems engineering strategies, aligning cross-functional teams, and ensuring rigorous safety and performance standards throughout the produ...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$132K - $165K *

Shape the future of billing and collections by driving product strategy and enhancing user experiences. Collaborate with cross-functional teams to deliver reliable payment solutions that boost revenue...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$137K - $245K *

Shape the future of physical operations by driving AI-powered product innovation. Collaborate across teams to identify customer needs, prototype solutions, and deliver impactful products that enhance...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$137K - $245K *

Lead the charge in driving strategic initiatives and product innovation within the Telematics Business Unit, enhancing core offerings and exploring new market opportunities through hands-on collaborat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $105K *

Unlock potential by leading complex IT projects in healthcare, ensuring alignment with clinical workflows and regulatory standards. Utilize your expertise to deliver impactful, patient-centered techno...

Reposted 1 month ago

  •   Less than 5 years exp.  •   Healthcare

$295K - $463K *

Elevate your career by leading an integrated organization focused on Data and AI Governance, Architecture, and Products. Drive enterprise strategy into actionable outcomes while fostering innovation a...

Today

  •   11 - 15 years exp.  •   Hospitality & Recreation

$295K - $463K *

Transform the future of data and AI by leading an integrated organization that drives governance, architecture, and product development, ensuring scalable, secure, and high-value capabilities aligned...

Today

  •   11 - 15 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.