Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$115K - $275K *

Manage the delivery of GPU clusters for AI workloads by coordinating teams across engineering, networking, and operations. Develop strategies, manage risks, and ensure timely, quality launches to scal...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Manage implementation projects, ensuring clear ownership and accountability across complex customer engagements while maintaining rigorous oversight of critical paths and deliverables for timely launc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $120K *

Deliver comprehensive project management for complex industrial construction, ensuring timely execution, budget adherence, and alignment with organizational goals while leading cross-functional teams...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $200K *

Empower partner operations by leading strategy, optimizing processes, and enhancing tools for a diverse global partner ecosystem. Collaborate cross-functionally to ensure scalable infrastructure and m...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$122K - $212K *

Take ownership of process optimization and digital operations to enhance Clinical Risk Management. Drive user engagement, coordinate vendor relations, and ensure audit readiness while implementing str...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $212K *

Join a dynamic team to enhance Clinical Risk Management through process optimization and digital operations. Drive user engagement, coordinate vendor relations, and ensure audit readiness while implem...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $212K *

Help us drive operational excellence in Clinical Risk Management by optimizing processes and managing digital operations. Collaborate with stakeholders to enhance user engagement and ensure audit read...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $130K *

Inspire innovation by managing the full product lifecycle for specialty doors, driving market strategies, and collaborating cross-functionally to enhance product offerings and profitability...

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$107K - $130K *

Lead the end-to-end product development lifecycle for specialty doors, driving market strategies and cross-functional initiatives to enhance product positioning, pricing, and profitability while colla...

Greensburg, PARemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $186K *

Transform procurement strategies by leading vendor management and building strategic partnerships. Drive operational efficiency while optimizing spend and enhancing supplier performance to support lon...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$120K - $204K *

Lead a talented team in developing the Epicor Identity Platform, blending hands-on programming with strategic guidance. Collaborate closely with product management and customers to deliver secure auth...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $204K *

Drive innovation in cloud identity platforms while leading a product development team. Balance technical expertise and people leadership to deliver robust solutions, collaborate with partners, and sha...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Execute comprehensive program management for a critical Air Force contract, leading a diverse team to ensure compliance, quality, and performance across multiple global operations while maintaining 24...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$115K - $135K *

Join a team that's transforming Medicaid agencies through expert OCM strategies. Leverage your project management and change management skills to enhance health outcomes and build stronger communities...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$95K - $115K *

Join a team that's driving transformative change through strategic analysis and execution. This high-visibility role collaborates with leadership to ensure progress on critical initiatives and enhance...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Join us in shaping the future of Fair Lending solutions. Drive product strategy, deliver expert analysis, and enhance client outcomes while navigating complex regulatory landscapes. Your expertise wil...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $200K *

Unlock potential by leading a global Deal Center of Excellence, enhancing strategic partnerships and commercial capabilities across the pharmaceutical and biotechnology sectors, while driving sustaina...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $175K *

Join a team that's redefining AI-driven solutions by leading product development for an innovative tech concierge. Drive the evolution of agent capabilities, ensuring quality and reliability while col...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $101K *

Lead the charge in executing client transition projects, managing onboarding and account expansions. Collaborate with teams to ensure seamless experiences while overseeing budgets, timelines, and stak...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Optimize engagement and monetization strategies for an AI-driven product, transforming customer interactions into measurable growth. Lead cross-functional teams to innovate and implement effective use...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$217K - $298K *

Lead the charge in shaping Root's platform and AI engineering strategy, overseeing critical infrastructure and driving operational excellence across teams to deliver intelligent products at scale...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $115K *

Transform your career by leading financial strategy and operations for innovative service lines. Collaborate with senior leaders to enhance profitability, oversee budgeting, and drive growth initiativ...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead a team that drives client success through strategic guidance, managing large-scale programs, and fostering strong relationships. Ensure exceptional delivery and compliance while identifying growt...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.