Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$150K - $180K *

Lead the charge in transforming partner data operations and integrations, ensuring efficient case resolution and proactive partner enablement. Drive automation, establish standards, and foster a produ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead the charge in shaping global healthcare packaging design. As a Principal Design Program Manager, you'll establish frameworks and standards, drive strategic decisions, and ensure seamless collabor...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $258K *

Join a dynamic team driving Master Data Management strategies to enhance data governance and operational efficiency across global orthopedic initiatives. Lead cross-functional collaboration to ensure...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion the successful delivery of projects and technology initiatives by coordinating cross-functional teams and managing risks, ensuring timely and high-quality outcomes that align with business ob...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $155K *

Join a team that's redefining Field Intelligence by leading technology strategy and product management. Drive innovation in analytics and AI to enhance decision-making and field effectiveness across a...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$77K - $126K *

Take ownership of managing construction projects, ensuring timely, on-budget delivery while collaborating with vendors and adhering to guidelines. Drive process improvements and maintain comprehensive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$500K+*

Lead the execution of carbon transaction advisory across LAC countries, managing senior government relationships and developing commercialization strategies to support forest protection initiatives an...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$160K - $190K *

Join a team that's redefining the Umbrella line of business by overseeing P&L, driving innovative strategies, and collaborating across departments to achieve profitable growth and enhance customer sat...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$136K - $171K *

Pioneer clinical trial excellence by leading operational planning and execution. Collaborate cross-functionally to ensure compliance, quality, and timely delivery of clinical studies while mentoring j...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Champion scalable deal operations by leading the Global Deal Desk, optimizing complex agreements across sales, finance, and legal. Drive AI integration to enhance workflows and ensure compliance while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$152K - $190K *

Lead the charge in product strategy and outcomes across diverse portfolios, connecting customer needs with business objectives. Develop and mentor a team of Product Managers while driving impactful pa...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$130K - $154K *

Lead complex projects to enhance organizational efficiency, manage timelines, and coordinate cross-functional teams. Drive strategic goals while ensuring compliance and fostering strong stakeholder re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $175K *

Empower engineering teams to enhance assessment services through leadership, technical expertise, and responsible AI adoption. Drive team performance and customer outcomes across diverse product areas...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$146K - $215K *

Empower supplier development by leading a team to enhance manufacturing capabilities, drive performance improvements, and ensure operational readiness for special processes and mechanical assembly, su...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$108K - $130K *

Lead and manage complex HR initiatives, collaborating across teams to drive strategic outcomes. Balance priorities, mitigate risks, and ensure successful project delivery while influencing diverse sta...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K *

Elevate client success by leading innovative training programs that enhance learning experiences. Drive product adoption and satisfaction through tailored onboarding and ongoing education, ensuring cl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Deliver exceptional project management by leading teams, coordinating activities, and ensuring timely completion of large-scale construction projects while fostering a culture of safety and inclusion...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$210K - $240K *

Elevate your career by leading and optimizing Workday HCM practices, ensuring excellence in project delivery, client satisfaction, and team performance while managing complex client needs and driving...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $160K *

Join a team that's transforming internal IT operations to enhance service delivery and support growth. This hands-on leadership role requires strategic vision and operational expertise to modernize te...

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$88K - $105K *

Lead the charge in absence management, providing expert consultation on leave programs, compliance, and strategic client engagement to enhance workforce efficiency and drive business growth in the Eas...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$88K - $105K *

Manage and oversee medium-sized transmission and distribution projects, ensuring accountability for scope, schedule, cost, and quality. Coordinate cross-functional teams, identify risks, and develop c...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $130K *

Transform strategic customer programs by leading complex projects across global teams, ensuring successful product development and commercialization while managing budgets and stakeholder engagement t...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$108K - $145K *

Optimize material management strategies to enhance flow, reduce costs, and improve customer satisfaction. Lead production planning and ensure alignment between demand, capacity, and operational execut...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$175K - $210K *

Unlock potential by leading corporate controllership activities, driving financial reporting, and strengthening internal controls in a rapidly evolving finance function. Collaborate with executives to...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$75K - $90K *

Drive exceptional client outcomes by managing complex, cross-functional projects. Collaborate with diverse teams to ensure clarity, timely execution, and risk management, transforming strategy into ac...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.