Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$150K - $180K *

Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Oversee and manage all phases of electrical construction projects, ensuring timely completion, budget adherence, and compliance with safety standards while leading project teams and liaising with stak...

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $151K *

Shape the future of enterprise strategy by leading a diverse portfolio of programs and initiatives. Collaborate with cross-functional teams to drive measurable business value and ensure alignment with...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Elevate security project management by leading teams in installing advanced systems. Oversee multiple projects, ensuring effective communication and stakeholder satisfaction while managing resources a...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Engage with cross-functional teams to drive clinical trial success across regions. Leverage your expertise in project management and mentoring to ensure compliance, quality, and timely execution of st...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $202K *

Unlock commercial potential by executing transformation workstreams, collaborating with cross-functional teams, and delivering strategic insights to drive measurable results in a healthcare-focused en...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Contribute to operational excellence by overseeing revenue processes, enhancing patient satisfaction, and managing budgets. Lead initiatives to improve service quality and compliance while fostering a...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $190K *

Advance product strategy and innovation by leading cross-functional teams to drive the vision, roadmap, and delivery of shared commercial platforms, ensuring alignment with business priorities and tec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Lead cross-functional teams to execute program plans, manage resources, and ensure milestones are met. Collaborate with stakeholders to identify risks and drive quality outcomes while maintaining prog...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$91K - $190K *

Drive the charge in advancing Anaplan strategies, leading diverse teams to optimize solutions that align with business objectives. Collaborate with stakeholders to enhance the Anaplan ecosystem and en...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Join a team that's redefining change management in healthcare. Support the adoption of innovative informatics solutions, ensuring seamless transitions and user readiness across the Veterans Health Adm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$176K - $205K *

Lead the charge in executing complex capital projects and liquid processing strategies. Drive innovation and efficiency across manufacturing networks while mentoring engineering teams and ensuring pro...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$113K - $197K *

Unlock the potential of product strategy and execution by leading cross-functional teams to deliver innovative solutions. Drive enterprise transformations and ensure alignment with business objectives...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing project efficiency and effectiveness. Support PMO processes and tools while collaborating across departments to ensure successful project delivery aligned wit...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Transform customer onboarding by leading implementation projects, managing cross-functional teams, and ensuring timely delivery of data solutions. Drive stakeholder engagement and maintain project gov...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive impactful projects in electric utility by managing engineering design, client coordination, and business development. Leverage your expertise to enhance project scope, budget, and schedule while...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$101K - $125K *

Drive the execution of immersive projects by providing technical oversight and support, ensuring seamless integration and coordination with partners globally while maintaining high standards of qualit...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$150K - $250K *

Champion innovation by optimizing workflows and AI-driven operations to enhance efficiency across diverse business functions. Collaborate closely with teams to build scalable systems that drive real i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Lead a dynamic account management team, driving strategic relationships with major health systems. Foster high-touch engagement, ensuring customer success and operational excellence while directly man...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$95K - $115K *

Champion project success by coordinating business and technology initiatives, ensuring adherence to quality and regulatory standards while managing cross-functional teams to deliver on time and within...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $130K *

Manage construction projects for new builds and remodels, overseeing vendors and maintaining quality standards while ensuring timely delivery and adherence to budgets. Foster collaboration with stakeh...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$97K - $143K *

Join a team that's dedicated to enhancing digital finance products. Collaborate with stakeholders to define requirements, drive development, and ensure solutions meet user needs while fostering contin...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$127K - $175K *

Champion the execution of security and privacy initiatives, aligning cross-functional teams to reduce risks and enhance outcomes. Drive strategic planning, maintain clear communication, and prepare ex...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$157K - $283K *

Lead the charge in delivering large-scale infrastructure projects, managing client relationships, overseeing construction management efforts, and ensuring program success through strategic planning an...

RemoteRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.