Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$126K - $168K *

Lead the charge in shaping and executing product strategy for B2B learning solutions, driving innovation and market impact while collaborating with cross-functional teams to deliver high-quality produ...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Lead strategic M&A initiatives by analyzing opportunities, managing due diligence, and fostering relationships. Collaborate with cross-functional teams to drive growth and ensure alignment with corpor...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $200K *

Champion large-scale enterprise application initiatives, leading Agile teams to drive digital transformation, manage program execution, and ensure alignment with strategic objectives while fostering c...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $165K *

Join a team that's redefining insurance technology delivery by leading SaaS implementation programs. This hands-on role combines project management with team leadership to ensure successful client out...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by managing diverse EV projects, ensuring successful delivery through collaboration, strategic planning, and effective stakeholder engagement. Drive project excellence while naviga...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $200K *

Optimize technology risk management across the enterprise by leading proactive assessments, ensuring alignment with regulatory standards, and embedding risk insights into decision-making for cloud, cy...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the transformation of healthcare IT by managing ServiceNow projects, enhancing workflows, and ensuring seamless integration. Collaborate with cross-functional teams to deliver innovative solution...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to optimizing project planning and cost control for renewable energy initiatives. Lead efforts in scheduling, compliance, and reporting to ensure project success from ince...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$125K - $150K *

Lead the charge in integrating acquired businesses into a complex global organization. Develop and execute strategic integration roadmaps, ensuring business continuity and alignment with corporate goa...

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$95K - $115K *

Champion data excellence by leading master data management and governance initiatives. Drive operational continuity, enhance data quality, and implement automation across enterprise platforms while fo...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Shape market research strategies by collaborating with marketers to uncover customer insights, leveraging AI tools for enhanced analysis and synthesis, and driving actionable recommendations that infl...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$155K - $200K *

Drive the development and management of software teams, fostering a culture of trust and continuous learning while ensuring timely delivery of high-quality software products through Agile methodologie...

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$86K - $118K *

Lead the charge in managing complex healthcare projects, ensuring timely delivery and budget adherence while coordinating cross-functional teams and mitigating risks for strategic initiatives...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate product execution by translating client needs into actionable requirements, collaborating with engineering and data science teams to deliver standardized measurement solutions across various c...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Lead core banking system conversions for credit unions, ensuring seamless project delivery through effective stakeholder communication, data migration, and interface integration, while managing risks...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $155K *

Drive complex eDiscovery projects from initiation to completion, managing client relationships and overseeing a team. Ensure high-quality deliverables while navigating the EDRM lifecycle in a fast-pac...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$130K - $155K *

Transform complex eDiscovery projects by leading teams through the EDRM lifecycle, ensuring high-quality deliverables and strategic client partnerships in a fast-paced environment...

Philadelphia, PARemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Join a team that's redefining employee payment solutions. As an Implementation Manager, oversee the deployment of our SaaS product for diverse clients, ensuring successful integrations and fostering s...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in implementing strategic project management services for large-scale construction projects. Oversee design coordination, budget management, and team collaboration to ensure timely and...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $316K *

Lead a high-performing platform engineering organization to deliver secure, reliable infrastructure services globally. Drive strategy, execution, and operational management across cloud, AI, and core...

RemoteRemote

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$92K - $138K *

Drive product line success from conception to lifecycle, leading cross-functional teams to achieve strategic goals and enhance profitability while ensuring market alignment and competitive edge...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$92K - $138K *

Transform your career by leading product strategies from conception to market. Drive growth and profitability while collaborating with cross-functional teams to deliver innovative solutions that meet...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$137K - $235K *

Join a dynamic team to accelerate clinical trial projects, leveraging your project management expertise and leadership skills to drive successful product launches and enhance collaboration across depa...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Join us to lead clinical trial project management, driving innovation and accelerating product launches through strategic partnerships and expert facilitation across teams. Your leadership will enhanc...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.