Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$83K - $155K *

Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead project management efforts, ensuring technical accuracy and client satisfaction while overseeing budgets, schedules, and team performance for civil engineering projects. Drive successful project...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Drive innovative water/wastewater solutions by managing projects, ensuring technical accuracy, and collaborating with teams to meet community needs and regulatory standards while delivering on time an...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Unlock your leadership potential by driving large-scale projects from inception to completion, ensuring excellence in execution, client satisfaction, and strategic growth through relationship building...

Reposted 4 weeks ago

  •   15+ years exp.  •   Real Estate & Construction

$110K - $130K *

Engage your expertise to lead complex HL7 integrations across healthcare systems, enhancing interoperability and data-sharing capabilities. Collaborate with stakeholders to ensure successful implement...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive project success by managing the lifecycle of electric distribution and substation projects, ensuring coordination with stakeholders, adherence to budgets, and timely execution across multiple co...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Drive enterprise-wide SAP S/4HANA enhancements by leading complex IT projects, managing cross-functional teams, and ensuring alignment across stakeholders while overseeing the full project lifecycle a...

5 days ago

  •   8 - 10 years exp.  •   Staffing

$100K - $150K *

Lead the charge in managing complex, technically sophisticated projects, focusing on data centers. Collaborate with diverse stakeholders to ensure project alignment with client goals, budgets, and sch...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$195K - $230K *

Drive growth by leading go-to-market strategies for TMC partnerships, building and executing plans from the ground up. Collaborate cross-functionally to influence product development and represent the...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $281K *

Join a team that's driving strategic client engagement and operational excellence. As a senior leader, you'll oversee program management, enhance client relationships, and ensure financial performance...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $145K *

Engineer innovative systems and processes to enhance product delivery, ensuring cross-functional teams operate efficiently and effectively. Drive execution, manage stakeholder alignment, and facilitat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $91K *

Empower project success by managing timelines, communications, and risk while ensuring collaboration across teams. Drive quality and safety standards to exceed expectations throughout the project life...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$200K - $250K *

Champion product security initiatives by leading a skilled team, architecting compliance frameworks, and managing incident response to enhance trust across all products and stakeholders...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Lead complex IT projects, driving cross-functional initiatives and organizational change. Collaborate with stakeholders to ensure successful technology implementation and continuous improvement, manag...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Optimize facility operations by leading maintenance teams across multiple sites, managing budgets, and overseeing construction projects. This role combines strategic planning with hands-on maintenance...

Yesterday

  •   Less than 5 years exp.  •   Staffing

$180K - $200K *

Manage the campaign calendar and ensure timely launches by transforming customer requests into actionable specs. Collaborate with cross-functional teams to maintain project alignment and drive success...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape strategic program execution by leading cross-functional initiatives that drive technology-enabled transformation and measurable business outcomes, partnering with executive teams to align object...

Yesterday

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Lead financial planning and analysis for the Commercial organization, driving budgeting, forecasting, and reporting. Collaborate with leaders to optimize resource allocation and support strategic deci...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$122K - $177K *

Unlock potential by leading HRIS strategy and optimization, overseeing a team to enhance Workday and UKG systems. Drive transformation and collaboration across HR, Finance, and Operations for impactfu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Shape the future of healthcare by leading AI-driven growth initiatives across HCP and patient journeys. Drive measurable brand impact through innovative AI solutions while navigating a regulated envir...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Drive the evolution of our enterprise analytics platform by leading cross-functional teams, managing stakeholder relationships, and delivering high-quality analytics solutions that meet business needs...

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $115K *

Join a team that's redefining healthcare project management. Lead integrated initiatives, mentor talent, and drive excellence across diverse campaigns while fostering collaboration and innovation in a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Take ownership of customer-facing products that enhance user journeys. Drive growth through experimentation and data analysis, maximizing conversion and retention while partnering with cross-functiona...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.