Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$126K - $191K *

Lead the charge in implementing an integrated risk framework across the enterprise, enhancing resilience and oversight while guiding teams in risk management, business continuity, and crisis response...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$93K - $159K *

Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in engineering excellence, overseeing a team of 60 while driving AI initiatives and enhancing operational strategies. Collaborate with product leadership to elevate engineering practic...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $135K *

Innovate and lead client engagements, driving strategic insights and integrated solutions in a fast-paced healthcare environment while mentoring cross-functional teams towards operational excellence a...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $110K *

Drive critical cross-functional initiatives, bridging strategy and execution to enhance mobile and fixed video services. Lead project management, streamline operations, and deliver impactful reporting...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $130K *

Champion global expansion initiatives by managing the FedRAMP program. Collaborate with cross-functional teams to ensure project timelines and deliverables are met while navigating a fast-paced enviro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by driving strategic partnerships and expanding client relationships. Lead business growth initiatives while effectively managing complex accounts in the clinical research sector. Col...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in expanding strategic partnerships and driving growth initiatives with autonomy. Collaborate with leadership to assess market trends, enhance client relationships, and achieve sales t...

Raleigh, NCRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K *

Unlock potential by leading the strategy and execution of hardware and support services for veterinary practices, driving P&L performance, vendor relationships, and cross-functional collaboration to e...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $190K *

Lead the charge in shaping data platform strategies and governance, driving innovative solutions and team development. Collaborate with partners to enhance AI readiness and ensure successful technical...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead a dynamic team in managing customer orders, ensuring accuracy and timely delivery while enhancing interdepartmental collaboration and customer satisfaction across Sales and Service Delivery opera...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Manage a dynamic team of BDRs to drive sales growth, enhance performance, and implement best practices. Collaborate with cross-functional teams to optimize opportunity management and ensure successful...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Shape the future of project management by leading software implementations, fostering stakeholder relationships, and delivering quality results in complex environments. Collaborate with clients to ens...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Join us to lead hyperscale data center construction projects across the U.S. Oversee all phases, manage teams, ensure quality and safety, and drive projects to completion on time and within budget whi...

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$93K - $124K *

Elevate your career by leading QA/QC activities across diverse construction projects, ensuring compliance with quality standards and driving corrective actions to enhance project outcomes and client s...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$154K - $258K *

Unlock potential by leading high-stakes mega-projects, driving strategic vision, and fostering talent development. Influence financial performance and mitigate risks while ensuring alignment across di...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$135K - $155K *

Drive impactful data solutions by bridging business needs with engineering teams. Own project intake, prioritize requests, and ensure clear communication across departments to enhance efficiency and d...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $150K *

Unlock potential by leading the vision and strategy for a transformative platform that integrates AI and data intelligence, driving impactful solutions across a dynamic product ecosystem in a collabor...

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$154K - $258K *

Drive strategic vision and execution for complex mega-projects, ensuring alignment across portfolios. Lead teams, mentor future leaders, and optimize financial performance while managing risks and fos...

5 days ago

  •   8 - 10 years exp.  •   Business Services

$136K - $160K *

Drive global procurement strategies and foster client relationships while overseeing multi-regional teams. Lead sourcing initiatives, ensure compliance, and deliver measurable value aligned with clien...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$135K - $160K *

Lead the charge in scaling our Customer Success Management team, driving product adoption and retention across diverse customer segments. Collaborate cross-functionally to create impactful processes a...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$180K - $200K *

Champion payroll excellence by leading global teams to innovate and automate processes while ensuring compliance and operational efficiency across multiple jurisdictions...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$125K - $185K *

Lead the charge in delivering strategic category value by orchestrating client-centric Design & Construction initiatives that align with operational goals, ensuring effective delivery through an innov...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$138K - $165K *

Elevate our product management efforts by driving innovation in cybersecurity. Collaborate with cross-functional teams to deliver impactful data-driven analytics, leveraging user insights and industry...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.