Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$120K - $145K *

Join a team that's driving partnership success through strategic build and optimization. Leverage your expertise to enhance collaboration, streamline processes, and ensure high-quality delivery across...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Help us deliver critical energy infrastructure projects by managing complex EPC initiatives, ensuring reliability and performance across all stages from planning to execution, while collaborating with...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Champion innovative oncology strategies by coordinating pre-award activities, enhancing client relations, and collaborating with global teams to drive successful outcomes in clinical research and busi...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Lead the charge in developing competitive oncology strategies, ensuring client needs are met through collaboration and expertise. Drive business development and enhance client relations while overseei...

Raleigh, NCRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Lead diverse land development projects, guiding teams through design, approvals, and construction. Foster collaboration in a fast-paced environment while managing budgets and mentoring junior engineer...

5 days ago

  •   5 - 7 years exp.  •   Technical Services

$165K - $175K *

Unlock potential by leading enterprise data engineering initiatives, driving platform modernization, and enhancing operational excellence. Collaborate with cross-functional teams to deliver scalable...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Healthcare

$170K - $180K *

Lead the strategic execution of commercial planning and sales coverage, aligning cross-functional teams to drive profitable growth. Oversee territory design, customer segmentation, and annual planning...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by providing strategic leadership for a national remote case management team, ensuring service excellence, operational consistency, and client satisfaction while collaborating with...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$135K - $210K *

Advance product development by managing end-to-end processes, collaborating with cross-functional teams, and driving timelines. This role requires a proactive approach to navigate ambiguity and ensure...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive project success by leading teams, managing schedules, and ensuring safety compliance. Build strong relationships with clients and stakeholders while overseeing project operations from preconstru...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $145K *

Transform the future of tax compliance by building a scalable filing platform and remittance infrastructure, enabling seamless global transactions and automation for international sellers. Drive innov...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Lead the charge in optimizing procurement and supply chain strategies, ensuring timely delivery of materials and services while fostering team development and sustainable practices to enhance project...

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$190K - $275K *

Advance the Data & Distribution Partnerships function by innovating and scaling data reseller and distribution models, building commercial arrangements, and leading a team to create revenue-generating...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Join a dynamic team to lead complex capture efforts, engaging with federal and commercial markets. Leverage your Special Operations expertise to shape mission-critical opportunities and ensure discipl...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Drive impactful program management by leading cross-functional initiatives, ensuring alignment with strategic goals, and delivering measurable results in a dynamic environment. Collaborate effectively...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$175K - $220K *

Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$205K - $240K *

Shape the future of supply chain technology by leading engineering teams in optimizing platforms for logistics and order management. Drive innovation and efficiency while managing a diverse team of ex...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$107K - $183K *

Shape global Technical Services operations by leading complex programs that enhance customer experience. Collaborate cross-functionally to establish standards, drive improvements, and ensure seamless...

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in product strategy and execution for Driver and Rider applications, ensuring a seamless user experience across mobile and web platforms while collaborating closely with engineering an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $147K *

Inspire and elevate employee engagement through strategic internal communications. Collaborate with leaders to craft and deliver impactful messaging that drives understanding of company goals and fost...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $190K *

Transform project delivery in the Power & Energy sector by leading engineering teams, managing complex projects, and ensuring quality outcomes through strategic oversight and innovative practices acro...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $140K *

Drive product innovation by leading the development of AI-enabled solutions for public sector agencies, enhancing early childhood systems through strategic vision, technical architecture, and customer...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$175K - $400K *

Elevate your career by managing the lifecycle of vendor agreements and contracts. Collaborate across departments to ensure compliance and streamline workflows, safeguarding business interests while mi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's enhancing public facilities through effective project management of nationwide repair and alteration projects, ensuring compliance, efficiency, and quality outcomes across diverse c...

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$114K - $143K *

Drive operational excellence as a Program Manager, enhancing EPD processes and collaboration. Leverage data insights to identify trends, improve efficiency, and support cross-functional teams in a dyn...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.