Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$185K - $255K *

Transform the financial engine of R&D by leading revenue strategies, pricing, and cost management. Collaborate with senior leaders to align short-term goals with long-term product vision, while buildi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$201K - $251K *

Lead strategic forecasting initiatives to drive decision-making in oncology. Collaborate with cross-functional teams to develop long-term models and communicate insights that shape product and portfol...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive operational excellence by leading multiple manufacturing work centers to meet safety, quality, and productivity goals. Collaborate with cross-functional teams to enhance performance and implemen...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $145K *

Elevate your career by leading a team to analyze and enhance Auto product performance, leveraging AI insights to drive growth and profitability while collaborating with key stakeholders to shape futur...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Take ownership of diverse industrial projects, delivering under budget and on schedule while providing on-site leadership. Engage with multi-disciplinary teams and manage client expectations in a dyna...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the execution of complex client programs, ensuring timely delivery and budget adherence. Collaborate with cross-functional teams to drive accountability and clarity, while proactively managing ri...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$123K - $155K *

Lead and manage large-scale technology projects, ensuring alignment with business goals and adherence to standards. Collaborate with cross-functional teams to deliver successful outcomes while mentori...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $100K *

Transform your career by managing technology projects that drive business success. Collaborate with cross-functional teams to ensure projects are delivered on time, within scope, and budget while adhe...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the charge in transforming marketing operations through innovative MarTech solutions, driving student and partner success while optimizing efficiency across a multi-brand ecosystem. Own product s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$95K - $192K *

Join a team that's driving large-scale Microsoft 365 and infrastructure projects. This client-focused role demands project leadership, ensuring quality implementation and client satisfaction while man...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $192K *

Engage clients by leading Microsoft 365 and infrastructure projects, managing all phases from discovery to post-implementation support, ensuring deliverables align with business objectives, timelines...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $256K *

Join a team that's redefining CMC strategies in life sciences. You'll engage with industry leaders, drive software adoption, and shape market narratives to enhance product lifecycle management and ope...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive project quality excellence in Electrification and Automation. Lead customer QMiP for large industrial clients, ensuring compliance with quality standards and fostering cross-functional collabora...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Lead and develop a high-performing team to optimize global supply chain solutions, ensuring compliance with standards while driving continuous improvement. Collaborate across departments to enhance st...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $178K *

Transform data governance by leading initiatives that bridge legal compliance, data security, and technology operations. Drive innovative self-service workflows while ensuring compliance across divers...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$132K - $220K *

Lead the charge in managing Renewable Energy Hydro Projects, driving execution strategies to maximize performance, ensuring timely delivery, and fostering strong customer relationships while overseein...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$188K - $282K *

Drive design excellence in fintech by leading a team to enhance payment, billing, and timekeeping solutions. Collaborate with cross-functional partners to shape user experiences that empower legal pro...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$232K - $290K *

Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$130K - $160K *

Drive program success by coordinating cross-functional teams, managing reporting, and optimizing engagement strategies for a global enterprise account, ensuring alignment with client goals and employe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Shape impactful healthcare solutions by leveraging your Epic Professional Billing expertise. Collaborate with diverse teams to optimize systems, enhance workflows, and drive meaningful results for cli...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Shape and elevate business operations and account management, driving resource optimization and client satisfaction. Collaborate with leadership to enhance project delivery and expand client relations...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$126K - $167K *

Transform your future by leading a dynamic team of electrical engineers in our Mission Critical Department. Elevate project outcomes while driving accountability, fostering growth, and cultivating inn...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$101K - $126K *

Engage in the design and execution of diverse architectural projects, leading multi-disciplinary teams to innovate and exceed client expectations while ensuring a collaborative process throughout the...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Lead the charge in overseeing complex clinical trials, ensuring timely execution and adherence to budget. Drive collaboration across teams while maintaining high standards for project delivery and sta...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Unlock your potential as you own the financial performance of a dynamic business unit, driving strategic decisions and enhancing visibility to shape impactful processes and outcomes. Join a hands-on l...

Morrisville, NCRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.