Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$80K - $90K *
Launch your design career by creating user-driven experiences and collaborating with cross-functional teams. Develop wireframes, prototypes, and polished UI while growing your skills in a dynamic envi...
Reposted 4 days ago
$73K - $212K *
Lead innovative AI solutions as a Manager in Data and Analytics Engineering. Supervise teams, manage client accounts, and drive exceptional results while fostering relationships and embracing technolo...
3 weeks ago
Customer Partner, Leader (Operations)
$147K - $215K *
Optimize customer partnerships by driving operational excellence, resolving site challenges, and enhancing system performance. Collaborate with cross-functional teams to ensure effective delivery of c...
Reposted yesterday
$120K - $150K *
Lead impactful communications strategies that enhance reputation and visibility. Collaborate with senior leaders to navigate complex issues, ensuring alignment with organizational goals while managing...
Yesterday
$163K - $322K *
Drive Finance Transformation initiatives by leading planning, forecasting, and performance management projects. Collaborate with teams to implement Anaplan solutions while managing deliverables and me...
3 weeks ago
$163K - $322K *
Unlock potential by leading Finance Transformation initiatives, managing project deliverables, and collaborating with cross-functional teams to implement Anaplan solutions. Coach junior members and dr...
3 weeks ago
$120K - $200K *
Drive account growth by managing client relationships and fostering strategic partnerships. This dynamic role engages with clients, executing sales strategies to expand product adoption while ensuring...
Reposted 1 week ago
Director, Value Consulting & Digital Transformation
$113K - $160K *
Champion the quantification of business impact from technology and transformation investments. Lead financial modeling and value realization efforts, translating insights into actionable recommendatio...
1 week ago
Senior Manager Trade Compliance
$134K - $241K *
Champion trade compliance by leading a team to ensure adherence to regulations, manage risks, and implement strategies that align with business goals while fostering a culture of integrity and innovat...
3 days ago
Senior Manager, Firmware Engineering
$166K - $216K *
Drive the development of innovative cardiac monitoring firmware by leading a dynamic team, enhancing engineering practices, and collaborating cross-functionally in a fast-paced, regulated environment...
Reposted 1 week ago
$120K - $150K *
Lead the charge in developing strategic frameworks that translate business objectives into actionable insights. Collaborate cross-functionally to identify growth opportunities and influence decision-m...
2 weeks ago
$166K - $200K *
Shape the future of healthcare technology by leading engineering for patient-centric systems. Drive innovation, ensure compliance, and mentor teams to deliver safe, efficient clinical solutions that e...
1 week ago
$90K - $110K *
Elevate your career by managing a diverse portfolio of retail and industrial properties across multiple states. This hands-on role focuses on operational excellence, financial performance, and tenant...
1 week ago
Senior Product Manager, Payments Gateway
$160K - $180K *
Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...
1 week ago
General Manager, Agent Management
$150K - $180K *
Accelerate progress at the forefront of AI management by owning strategy, driving revenue, and leading cross-functional teams to establish a new product category from inception to $100M...
Today
$80K - $95K *
Lead and manage construction projects from inception to completion, ensuring quality and efficiency. Collaborate with teams to deliver exceptional results while navigating challenges and maintaining c...
4 days ago
Director, Product Management and Downstream Marketing
$150K - $180K *
Shape the future of life sciences by leading a high-performing Product Management and Marketing team. Drive portfolio strategy, commercialization, and business growth while collaborating across functi...
4 days ago
$134K - $265K *
Lead technical strategy and architecture for Salesforce implementations, guiding multi-industry teams to deliver innovative solutions that enhance client engagement and drive business growth through e...
Yesterday
$134K - $265K *
Lead the charge in Salesforce technical strategy and architecture, guiding multi-industry teams to deliver innovative solutions. Leverage your expertise to enhance client engagements and drive measura...
Yesterday
$120K - $145K *
Transform your career by driving VAR growth across North America. Lead partner recruitment, develop strategic plans, and enhance sales execution to achieve sustainable revenue growth in the mid-market...
1 week ago
Senior Product Manager, Growth
$181K - $213K *
Transform product-led growth by crafting data-driven strategies, enhancing customer experiences with AI, and driving account expansion through collaboration and experimentation across teams...
3 weeks ago
Project Engineer, Electrical Procurement
$80K - $95K *
Unlock your potential by managing sourcing and procurement for electrical projects. Collaborate with teams to ensure timely delivery of materials while mitigating risks and maintaining quality standar...
2 weeks ago
Data Engineering, Management, & Governance Manager - Finance
$87K - $253K *
Innovate data solutions by building and optimizing scalable data pipelines, ensuring quality and governance while leveraging cloud technologies and best practices in data engineering and management...
2 weeks ago
$80K - $95K *
Transform quality assurance processes by leading the development and implementation of a robust Quality Management System (QMS) in an automotive manufacturing environment, ensuring compliance and driv...
4 days ago
$125K - $150K *
Engage with enterprise customers to drive growth and success through strategic account management. Build relationships, execute tailored strategies, and leverage industry expertise to expand major acc...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.