Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$160K - $180K *
Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...
1 week ago
$88K - $105K *
Drive project management excellence by overseeing engineering solutions that exceed client expectations, ensuring timely delivery and budget adherence while collaborating with diverse teams and stakeh...
Yesterday
Director - Owner Representative Program
$165K - $200K *
Transform federal programs by leading owner's representative services, ensuring effective project delivery from inception to closeout. Leverage commercial real estate expertise to advocate for owners...
1 week ago
Event Project Manager, Corporate Meetings & Events
$75K - $94K *
Lead the charge in managing AV production for corporate events, ensuring seamless execution and client satisfaction. Collaborate with diverse industries, guiding projects from inception to completion...
Today
Director, Project Engineering - Remote US
$155K - $195K *
Oversee project engineering initiatives for new facility construction and technology deployment. Collaborate with cross-functional teams to ensure successful implementation and compliance, while leadi...
3 days ago
Project Manager- Manufacturing
$88K - $105K *
Partner with us to drive manufacturing excellence by managing project planning, budgeting, and execution. Collaborate across teams to ensure timely delivery, optimize resources, and enhance operationa...
3 weeks ago
$69K - $119K *
Elevate your career by managing diverse projects in healthcare, ensuring timely delivery and quality. Collaborate with teams to implement best practices, drive innovation, and enhance client experienc...
2 days ago
$90K - $92K *
Join a dynamic team as you support project execution and management for USACE maintenance tasks. Collaborate with stakeholders, track performance metrics, and guide project teams to ensure successful...
3 days ago
Senior Project Manager, Mechanical Procurement
$100K - $120K *
Lead the charge in complex HVAC procurement, mentoring junior staff while enhancing supplier partnerships and driving process improvements across multiple projects to maximize efficiency and revenue o...
2 weeks ago
$162K - $243K *
Lead a dynamic team in managing complex clinical research trials, ensuring strategic execution and client satisfaction. Drive project success through effective communication, budget oversight, and qua...
Reposted 1 week ago
$162K - $243K *
Lead a dynamic team in managing complex clinical research trials, ensuring project execution aligns with strategic objectives. Drive process improvements and maintain client relationships while overse...
2 weeks ago
Manager, Operations Program Management
$125K - $211K *
Lead a dynamic team to drive successful hardware product launches, managing cross-functional operations from concept to mass production. Elevate your career in a fast-paced environment focused on inno...
Today
Project Manager, Electrical Procurement
$88K - $105K *
Manage procurement strategies for electrical materials across multiple projects. Collaborate with vendors and teams to ensure timely delivery and cost-effective purchasing while mitigating risks and m...
2 weeks ago
Technology Project Manager (Insurance Industry)
$118K - $222K *
Drive the future of technology delivery by leading cross-functional teams to achieve business outcomes. Leverage Agile methodologies and emerging AI capabilities to enhance project execution, stakehol...
Reposted 2 days ago
$113K - $188K *
Pioneer a transformative Agile project management role overseeing large-scale software development. Lead coordination and execution across multiple teams and workstreams while ensuring alignment with...
Reposted 1 week ago
Project Manager I - Medical Devices
$120K - $190K *
Lead the charge in ensuring compliance for medical devices by managing audits, reviewing documentation, and collaborating with clients. Utilize your expertise in regulatory frameworks to drive quality...
3 days ago
Project Manager, Industrial Controls Implementation
$116K - $170K *
Join a dynamic team to drive the planning and execution of PLC updates, ensuring seamless operations across automated warehouse sites while coordinating with cross-functional partners and enhancing de...
Reposted 1 week ago
$120K - $145K *
Join a dynamic team as you drive product strategy and AI integration, ensuring innovative solutions meet market needs. Collaborate cross-functionally to enhance user experiences and deliver high-value...
5 days ago
Director, Partner Management, Americas
$195K - $241K *
Partner with us to drive growth and adoption across a diverse product portfolio, managing strategic partnerships from design to launch. Collaborate cross-functionally to enhance relationships and ensu...
2 weeks ago
Sr. Consultant / Project Manager
$95K - $115K *
Empower client success by leading software implementation projects, fostering relationships, and driving innovation. Manage timelines and deliverables while ensuring satisfaction through expert guidan...
1 week ago
$95K - $115K *
Elevate your career by leading technology-driven manufacturing projects. Drive complex initiatives from concept to delivery, ensuring quality and profitability while collaborating with cross-functiona...
Reposted 1 week ago
Project Manager Data Center Rapid Deployment
$115K - $138K *
Manage complex data center deployment projects, ensuring timely delivery and alignment among stakeholders. Oversee planning, execution, and closeout while maintaining budget and risk controls in fast...
2 weeks ago
$95K - $115K *
Lead the charge in managing engineering and manufacturing projects, collaborating across teams to ensure timely execution, budget adherence, and high-quality outcomes that drive business growth and in...
2 days ago
$80K - $95K *
Champion operational excellence by managing AV/IT support contract performance, staffing, and compliance. Lead teams to enhance service delivery while ensuring cybersecurity adherence across all facil...
Reposted 1 week ago
Director, Production and Infrastructure Engineering
$240K - $290K *
Elevate your career by leading a dynamic engineering team focused on production and infrastructure. Drive performance, foster collaboration, and deliver innovative solutions while managing diverse tec...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.