Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
FEMA PA Program Delivery Manager
$70K - $150K *
Join a team that's dedicated to supporting disaster recovery efforts through federal funding programs. Collaborate with local governments and nonprofits to ensure compliance and effective project form...
Reposted 1 week ago
$94K - $179K *
Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...
1 week ago
Project Controls Lead - Data Center Construction
$160K - $190K *
Champion project control excellence by developing strategies, collaborating with teams, and optimizing performance to ensure successful project delivery within timelines and budgets. Lead initiatives...
2 weeks ago
$160K - $180K *
Lead the development of AI governance solutions, transforming research into market-ready products. Collaborate with cross-functional teams to ensure customer-focused outcomes and drive product success...
4 days ago
Director, Workforce Strategy & Transformation
$150K - $180K *
Champion strategic workforce planning and AI-driven work design to enhance capability, improve productivity, and advance internal mobility across teams. Drive tools and strategies aligning workforce p...
Reposted 1 week ago
$80K - $95K *
Transform field operations into effective learning solutions by bridging instructional design and hands-on training. Collaborate with stakeholders to identify performance gaps and develop competency-b...
6 days ago
Manager, IT Planning & Delivery
$99K - $164K *
Lead strategic IT planning and delivery oversight, aligning initiatives with business goals. Collaborate with leadership to optimize resources, enhance governance, and drive Agile practices within a d...
4 days ago
$109K - $164K *
Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...
Reposted 3 weeks ago
$110K - $125K *
Analyze customer needs and drive product initiatives using AI tools. Own features from discovery to delivery, ensuring alignment with business priorities and quality outcomes while collaborating acros...
1 week ago
Project Director-Industrial Construction
$185K - $235K *
Lead the charge in executing large-scale heavy industrial construction projects, ensuring safety, quality, and client satisfaction while managing budgets, schedules, and team performance from award th...
1 week ago
Project Director-Industrial Construction
$185K - $235K *
Empower your career by leading large-scale heavy industrial construction projects. Oversee execution, safety, budget, and client satisfaction while coordinating diverse teams and stakeholders to ensur...
1 week ago
Senior Manager, People Operations
$181K - $216K *
Empower the future of people operations by aligning strategy with business goals. Lead a dynamic team across HR functions, driving engagement, compliance, and organizational design while fostering a c...
Reposted today
Consultant, Technology Project Manager
$118K - $222K *
Deliver impactful technology solutions by managing workstreams, engaging stakeholders, and driving business outcomes. Collaborate across teams to ensure effective delivery, mitigate risks, and optimiz...
2 days ago
$80K - $95K *
Unlock potential by leading a multidiscipline team in architectural projects, ensuring code compliance, coordinating workflows, and delivering high-quality documents on schedule while fostering collab...
4 days ago
Manager, Foundry Engineering & Engineering Enablement
$110K - $130K *
Shape the future of engineering by leading Foundry solutions and enabling teams to deliver scalable, reliable applications. Collaborate across disciplines to establish best practices and drive innovat...
2 weeks ago
Director, Merchandising Operations
$145K - $180K *
Champion operational excellence by leading a dynamic team to enhance processes, drive complex projects, and ensure seamless collaboration across departments, all while improving patient outcomes in th...
3 days ago
Principal Product Manager, AI Workflows
$150K - $180K *
Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...
1 week ago
$125K - $150K *
Drive the transformation of our accounting function by leading the monthly close, enhancing financial systems, and developing a high-performing team. Leverage AI and automation to improve accuracy and...
2 weeks ago
Consulting Director, Environmental FERC
$125K - $150K *
Engage as a trusted advisor in environmental consulting, leading major natural gas and LNG projects. Drive permitting strategies, manage interdisciplinary teams, and foster client relationships while...
4 days ago
$120K - $140K *
Transform your career by leading product development initiatives that enhance enterprise reporting and analytics. Collaborate with cross-functional teams to deliver high-quality solutions that meet bu...
2 weeks ago
Project Delivery Manager - Renewable & Market Advisory | 1898 & Co.
$110K - $130K *
Drive strategic leadership and operational excellence in project delivery, guiding a team of consultants in the Renewables & Markets Advisory sector to achieve high-quality outcomes and foster profess...
3 weeks ago
$220K - $260K *
Elevate the buying experience by leading product strategy, enhancing catalog quality, and optimizing marketplace economics. Drive measurable outcomes through collaboration with operations and engineer...
4 weeks ago
Senior Director, Integrated Risk Management
$126K - $191K *
Lead the charge in implementing an integrated risk framework across the enterprise, enhancing resilience and oversight while guiding teams in risk management, business continuity, and crisis response...
2 weeks ago
Procurement Manager, Process & Policy
$93K - $159K *
Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...
2 weeks ago
$150K - $180K *
Lead the charge in engineering excellence, overseeing a team of 60 while driving AI initiatives and enhancing operational strategies. Collaborate with product leadership to elevate engineering practic...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.